Spots Global Cancer Trial Database for Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
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Trial Identification
Brief Title: Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Official Title: A Multicenter, Open-label, Phase 3 Study to Evaluate the Long-term Safety and Efficacy in Participants Who Are Currently on Treatment or in Follow-up in Studies That Include Pembrolizumab
Study ID: NCT03486873
Study Description
Brief Summary: The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who transition into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. Each participant will transition to this extension study in one of the following three phases, depending on the study phase they were in at the completion of the parent study. Participants who were in the First Course Phase of study treatment with pembrolizumab or lenvatinib in their parent study will enter the First Course Phase of this study and complete up to 35 doses or more every 3 weeks (Q3W) or 17 doses or more every 6 weeks (Q6W) of study treatment with pembrolizumab or a pembrolizumab-based combination or lenvatinib according to arm assignment. Participants who were in the Follow-up Phase in the parent study (post-treatment or Survival Follow-up Phase) will enter the Survival Follow-up Phase of this study. Participants who were in the Second Course Phase in their parent study will enter Second Course Phase of this study and complete up to 17 doses Q3W or 8 doses Q6W of study treatment with pembrolizumab or a pembrolizumab-based combination according to arm assignment. Any participant originating from a parent trial where crossover to pembrolizumab was permitted upon disease progression may be eligible for 35 doses as Q3W or 17 doses Q6W of pembrolizumab (approximately 2 years), if they progress while on the control arm and pembrolizumab is approved for the indication in the country where the potential eligible crossover participant is being evaluated.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Arizona Cancer Center ( Site 0018), Tucson, Arizona, United States
Comprehensive Blood & Cancer Center [Bakersfield, CA] ( Site 0054), Bakersfield, California, United States
California Cancer Associates for Research & Excellence ( Site 0016), Fresno, California, United States
The Angeles Clinic and Research Institute ( Site 0005), Los Angeles, California, United States
UCLA Hematology/Oncology - Westwood (Building 100) ( Site 0009), Los Angeles, California, United States
UCSF Helen Diller Family Comprehensive Cancer Center ( Site 0004), San Francisco, California, United States
Providence Saint John's Health Center ( Site 0059), Santa Monica, California, United States
University of Colorado Cancer Center ( Site 0021), Aurora, Colorado, United States
Yale Cancer Center ( Site 0014), New Haven, Connecticut, United States
Georgetown University Medical Center ( Site 0023), Washington, District of Columbia, United States
Holy Cross Hospital, Michael & Dianne Bienes Comp Cancer Ctr ( Site 0022), Fort Lauderdale, Florida, United States
Mount Sinai Medical Center Comprehensive Cancer Center ( Site 0031), Miami Beach, Florida, United States
Moffitt Cancer Center ( Site 0011), Tampa, Florida, United States
Emory School of Medicine ( Site 0013), Atlanta, Georgia, United States
Northwest Georgia Oncology Centers PC ( Site 0061), Marietta, Georgia, United States
Kaiser Permanente Moanalua Medical Center ( Site 0063), Honolulu, Hawaii, United States
The University of Chicago ( Site 0020), Chicago, Illinois, United States
University of Iowa Hospital and Clinics ( Site 0026), Iowa City, Iowa, United States
James Graham Brown Cancer Center ( Site 0058), Louisville, Kentucky, United States
MedStar Franklin Square Medical Center ( Site 0046), Baltimore, Maryland, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 0056), Baltimore, Maryland, United States
Massachusetts General Hospital ( Site 0041), Boston, Massachusetts, United States
Dana-Farber Cancer Institute ( Site 0006), Boston, Massachusetts, United States
Karmanos Cancer Institute ( Site 0047), Detroit, Michigan, United States
Mayo Clinic in Rochester, Minnesota ( Site 0002), Rochester, Minnesota, United States
Comprehensive Cancer Centers of Nevada ( Site 0043), Las Vegas, Nevada, United States
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0038), Hackensack, New Jersey, United States
Cancer Institute of New Jersey ( Site 0025), New Brunswick, New Jersey, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0032), New York, New York, United States
Memorial Sloan Kettering Cancer Center ( Site 0012), New York, New York, United States
White Plains Hospital-Center for Cancer Care ( Site 0069), White Plains, New York, United States
WakeMed Cancer Care - Waverly Hematology & Medical Oncology ( Site 0074), Cary, North Carolina, United States
University of North Carolina at Chapel Hill ( Site 0040), Chapel Hill, North Carolina, United States
Levine Cancer Institute ( Site 0034), Charlotte, North Carolina, United States
Duke Cancer Center ( Site 0028), Durham, North Carolina, United States
Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 0065), Fargo, North Dakota, United States
University Hospitals ( Site 0044), Cleveland, Ohio, United States
Oklahoma Cancer Specialists and Research Institute, LLC ( Site 0082), Tulsa, Oklahoma, United States
Providence Portland Medical Center ( Site 0051), Portland, Oregon, United States
St. Luke's University Health Network ( Site 0017), Bethlehem, Pennsylvania, United States
University of Pennsylvania ( Site 0010), Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center ( Site 0042), Philadelphia, Pennsylvania, United States
UPMC Hillman Cancer Center ( Site 0008), Pittsburgh, Pennsylvania, United States
Sanford Cancer Center ( Site 0066), Sioux Falls, South Dakota, United States
West Cancer Center and Research Institute ( Site 0055), Germantown, Tennessee, United States
Vanderbilt Health One Hundred Oaks Diagnostic ( Site 0060), Nashville, Tennessee, United States
Vanderbilt Ingram Cancer Center ( Site 0015), Nashville, Tennessee, United States
Texas Oncology-Baylor Sammons Cancer Center ( Site 0062), Dallas, Texas, United States
University of Texas MD Anderson Cancer Center ( Site 0007), Houston, Texas, United States
South Texas Accelerated Research Therapeutics, LLC (START) ( Site 0001), San Antonio, Texas, United States
University of Virginia Health System ( Site 0035), Charlottesville, Virginia, United States
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0075), Midlothian, Virginia, United States
Blue Ridge Cancer Care ( Site 0067), Roanoke, Virginia, United States
Seattle Cancer Care Alliance ( Site 0024), Seattle, Washington, United States
Centro de Oncología e Investigación de Buenos Aires ( Site 1357), Berazategui, Buenos Aires, Argentina
Hospital Aleman-Oncology ( Site 1351), Buenos Aires, Caba, Argentina
Clinica Viedma ( Site 1353), Viedma, Rio Negro, Argentina
Sanatorio Parque ( Site 1355), Rosario, Santa Fe, Argentina
Instituto de Oncologia de Rosario ( Site 1350), Rosario, Santa Fe, Argentina
Hospital Privado Universitario de Córdoba ( Site 1354), Cordoba, , Argentina
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 1358), La Rioja, , Argentina
Centro Medico San Roque-Oncology ( Site 1352), Tucuman, , Argentina
Chris OBrien Lifehouse ( Site 3003), Camperdown, New South Wales, Australia
Royal Prince Alfred Hospital-A.W. Morrow Gastroenterology and Liver Centre ( Site 3016), Camperdown, New South Wales, Australia
Liverpool Hospital-Medical Oncology ( Site 3021), Liverpool, New South Wales, Australia
Macquarie University ( Site 3010), Macquarie University, New South Wales, Australia
Mater Hospital Sydney ( Site 3007), North Sydney, New South Wales, Australia
Orange Hospital-Clinical Trials Unit ( Site 3027), Orange, New South Wales, Australia
Port Macquarie - Mid North Coast Cancer Institute-Medical Oncology ( Site 3020), Port Macquarie, New South Wales, Australia
Royal North Shore Hospital-Medical Oncology Clinical Trials ( Site 3025), St Leonards, New South Wales, Australia
Calvary Mater Newcastle ( Site 3005), Waratah, New South Wales, Australia
Westmead Hospital ( Site 3000), Westmead, New South Wales, Australia
Melanoma Institute Australia ( Site 3001), Wollstonecraft, New South Wales, Australia
Mater Misericordiae Limited-Medical Oncology ( Site 3019), Brisbane, Queensland, Australia
Gallipoli Medical Research Ltd ( Site 3011), Brisbane, Queensland, Australia
Royal Brisbane and Women s Hospital ( Site 3009), Herston, Queensland, Australia
Tasman Oncology Research Pty Ltd ( Site 3012), Southport, Queensland, Australia
The Townsville Hospital ( Site 3017), Townsville, Queensland, Australia
Princess Alexandra Hospital ( Site 3002), Woolloongabba, Queensland, Australia
Royal Adelaide Hospital ( Site 3014), Adelaide, South Australia, Australia
The Queen Elizabeth Hospital ( Site 3026), Woodville, South Australia, Australia
Monash Health ( Site 3015), Clayton, Victoria, Australia
Austin Health-Austin Hospital ( Site 3004), Heidelberg, Victoria, Australia
Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 3008), Melbourne, Victoria, Australia
St Vincent's Hospital-Oncology Clinical Trials ( Site 3018), Melbourne, Victoria, Australia
Western Health-Sunshine & Footscray Hospitals ( Site 3023), St Albans, Victoria, Australia
Ballarat Oncology & Haematology Services ( Site 3022), Wendouree, Victoria, Australia
Sir Charles Gairdner Hospital ( Site 3006), Nedlands, Western Australia, Australia
St John of God Subiaco Hospital ( Site 3013), Subiaco, Western Australia, Australia
Kepler Universitätsklinikum ( Site 2955), Linz, Oberosterreich, Austria
Medical University of Graz ( Site 2952), Graz, Steiermark, Austria
Medizinische Universitaet Innsbruck ( Site 2951), Innsbruck, Tirol, Austria
Uniklinikum Salzburg ( Site 2956), Salzburg, , Austria
Medizinische Universität Wien ( Site 2953), Wien, , Austria
Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 2954), Wien, , Austria
AZ Sint-Maarten ( Site 2904), Mechelen, Antwerpen, Belgium
Institut Jules Bordet ( Site 2903), Anderlecht, Bruxelles-Capitale, Region De, Belgium
UZ Brussel ( Site 2900), Brussels, Bruxelles-Capitale, Region De, Belgium
Cliniques Universitaires de Bruxelles - CUB - Hopital Erasme ( Site 2905), Bruxelles, Bruxelles-Capitale, Region De, Belgium
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi, Yvoir, Namur, Belgium
AZ Maria Middelares ( Site 2908), Gent, Oost-Vlaanderen, Belgium
UZ Leuven ( Site 2901), Leuven, Vlaams-Brabant, Belgium
UZ Leuven - Campus Gasthuisberg ( Site 2906), Leuven, Vlaams-Brabant, Belgium
UZ Leuven Gasthuisberg, Gynaecologie-Verloskunde ( Site 2907), Leuven, Vlaams-Brabant, Belgium
CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA-Pesquisa Clínica ( Site 1024), Fortaleza, Ceara, Brazil
ONCOSITE - Centro de Pesquisa Clinica em Oncologia ( Site 1008), Ijui, Rio Grande Do Sul, Brazil
Hospital de Clinicas de Porto Alegre ( Site 1000), Porto Alegre, Rio Grande Do Sul, Brazil
Hospital São Lucas da PUCRS-Centro de Pesquisa em Oncologia ( Site 1006), Porto Alegre, Rio Grande Do Sul, Brazil
Hospital Nossa Senhora da Conceição ( Site 1011), Porto Alegre, Rio Grande Do Sul, Brazil
Clinica Viver ( Site 1021), Santa Maria, Rio Grande Do Sul, Brazil
CEPON ( Site 1012), Florianópolis, Santa Catarina, Brazil
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 1010), Barretos, Sao Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto-Centro Integrado de Pesquisa ( Site, São José do Rio Preto, Sao Paulo, Brazil
Clínica de Pesquisa e Centro de Estudos em Ginecologia Oncológica e Mamária LTDA ( Site 1017), São Paulo, Sao Paulo, Brazil
Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA ( Site 1020), Rio de Janeiro, , Brazil
Instituto de de Educação, pesquisa e Gestão em Saúde ( Site 1014), Rio de Janeiro, , Brazil
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 1001), Sao Paulo, , Brazil
A. C. Camargo Cancer Center ( Site 1002), Sao Paulo, , Brazil
Cross Cancer Institute ( Site 2804), Edmonton, Alberta, Canada
Hamilton Health Sciences-Juravinski Cancer Centre ( Site 2801), Hamilton, Ontario, Canada
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 2808), Kingston, Ontario, Canada
London Regional Cancer Program - LHSC ( Site 2806), London, Ontario, Canada
The Ottawa Hospital - General Campus ( Site 2813), Ottawa, Ontario, Canada
Sunnybrook Research Institute ( Site 2802), Toronto, Ontario, Canada
Mount Sinai Hospital ( Site 2811), Toronto, Ontario, Canada
Princess Margaret Cancer Centre ( Site 2803), Toronto, Ontario, Canada
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre-Oncology ( Site 2809), Greenfield Park, Quebec, Canada
Centre Intégré de Santé et de Services Sociaux (CISSS) de La-Centre intégré de cancérologie de Lava, Laval, Quebec, Canada
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 2807), Montreal, Quebec, Canada
Jewish General Hospital ( Site 2800), Montreal, Quebec, Canada
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 2, Quebec, , Canada
James Lind Centro de Investigación del Cáncer ( Site 2757), Temuco, Araucania, Chile
Orlandi Oncologia-Oncology ( Site 2752), Santiago, Region M. De Santiago, Chile
Fundacion Arturo Lopez Perez FALP ( Site 2750), Santiago, Region M. De Santiago, Chile
Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 2751), Santiago, Region M. De Santiago, Chile
Instituto Nacional del Cancer-CR Investigación ( Site 2753), Santiago, Region M. De Santiago, Chile
Bradfordhill-Clinical Area ( Site 2756), Santiago, Region M. De Santiago, Chile
ONCOCENTRO APYS-ACEREY ( Site 2758), Viña del Mar, Valparaiso, Chile
Centro de Investigaciones ( Site 2755), Viña del Mar, Valparaiso, Chile
Anhui Provincial Hospital-Cancer Chemotherapy Department ( Site 3480), Hefei, Anhui, China
Anhui Provincil Hospital South District-Respiratory Medicine Dept ( Site 3487), Hefei, Anhui, China
Beijing Cancer Hospital ( Site 3451), Beijing, Beijing, China
Affiliated Hospital of Military Medical Science Academy of the PLA ( Site 3465), Beijing, Beijing, China
Beijing Cancer hospital-Thoracic Cancer Department A ( Site 3454), Beijing, Beijing, China
Beijing Peking Union Medical College Hospital-Medical Oncology ( Site 3466), Beijing, Beijing, China
Army Medical Center of People's Liberation Army-Oncology Department ( Site 3477), Chongqing, Chongqing, China
Fujian Provincial Cancer Hospital ( Site 3461), Fuzhou, Fujian, China
SUN YAT-SEN UNIVERSITY CANCER CENTRE-Internal Medicine ( Site 3452), Guangzhou, Guangdong, China
Sun Yat-sen University Cancer Center-melanoma ( Site 3482), Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital-Cancer Center ( Site 3462), Guangzhou, Guangdong, China
The First Affiliated Hospital, Sun Yat-sen University-pneumology department ( Site 3459), Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou Medical University-thoracic surgery department ( Site 346, Guangzhou, Guangdong, China
Harbin Medical University Cancer Hospital-Harbin Medical University Cancer Hospital ( Site 3475), Harbin, Heilongjiang, China
Tongji Hospital Tongji Medical,Science & Technology-oncology ( Site 3476), Wuhan, Hubei, China
Xiangya Hospital Central South University-Respiratory ( Site 3479), Changsha, Hunan, China
Hunan Cancer Hospital ( Site 3485), Changsha, Hunan, China
Jiangsu Cancer Hospital-Medical Oncotherapy ( Site 3469), Nanjing, Jiangsu, China
Northern Jiangsu People's Hospital-General Surgery Department ( Site 3474), Yangzhou, Jiangsu, China
The First Hospital of Jilin University-Oncology ( Site 3464), Changchun, Jilin, China
Jilin Province Tumor Hospital ( Site 3484), Changchun, Jilin, China
Tangdu Hospital of Fourth Military Medical University of Chi-department of radiotherapy ( Site 3455), Xi'an, Shaanxi, China
Fudan University Shanghai Cancer Center ( Site 3467), Shanghai, Shanghai, China
Shanghai Pulmonary Hospital ( Site 3470), Shanghai, Shanghai, China
West China Hospital Sichuan University-respiratory ( Site 3473), Cheng Du, Sichuan, China
Tianjin Medical University Cancer Institute and Hospital ( Site 3456), Tianjin, Tianjin, China
Hangzhou Cancer Hospital-Medical Oncology ( Site 3468), Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital ( Site 3481), Hangzhou, Zhejiang, China
Instituto de Cancerología-Oncology ( Site 2702), Medellín, Antioquia, Colombia
Oncomédica S.A.S ( Site 2703), Montería, Cordoba, Colombia
Administradora Country S.A. ( Site 2701), Bogota, Distrito Capital De Bogota, Colombia
Fundación Valle del Lili ( Site 2700), Cali, Valle Del Cauca, Colombia
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0703), Brno, Brno-mesto, Czechia
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0704), Olomouc, Olomoucky Kraj, Czechia
Fakultni Thomayerova nemocnice-Onkologicka klinika 1. LF UK ( Site 0702), Prague, Praha 4, Czechia
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 0705), Praha, Praha 5, Czechia
Fakultni nemocnice Olomouc ( Site 0701), Olomouc, , Czechia
Fakultni nemocnice v Motole ( Site 0700), Praha 5, , Czechia
Odense Universitetshospital ( Site 0650), Odense, Syddanmark, Denmark
Vejle Sygehus ( Site 0653), Vejle, Syddanmark, Denmark
Tartu University Hospital-Radiotherapy and oncology ( Site 3800), Tartu, Tartumaa, Estonia
Tampere University Hospital [Tampere Finland] ( Site 0600), Tampere, Pirkanmaa, Finland
Turku University Hospital ( Site 0601), Turku, Varsinais-Suomi, Finland
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Dermatology Department ( Site 2539), Nice, Alpes-Maritimes, France
Nouvel Hôpital Civil (NHC) ( Site 2529), Strasbourg, Alsace, France
CHU Bordeaux Haut-Leveque ( Site 2534), Pessac, Aquitaine, France
Centre Hopitalar Leon-Berard ( Site 2519), Lyon, Auvergne, France
Hopital Nord ( Site 2516), Marseille, Bouches-du-Rhone, France
CHU La Timone ( Site 2508), Marseille, Bouches-du-Rhone, France
Centre Georges François Leclerc-Centre de recherche clinique ( Site 2536), Dijon, Cote-d Or, France
CHU Jean Minjoz ( Site 2520), Besancon, Doubs, France
CHU de Brest -Site Hopital Morvan ( Site 2504), Brest, Finistere, France
Institut Bergonie ( Site 2502), Bordeaux, Gironde, France
CHU de Toulouse - Hopital Larrey-service de pneumologie ( Site 2526), Toulouse, Haute-Garonne, France
CHU Toulouse - Hopital Rangueil ( Site 2518), Toulouse, Haute-Garonne, France
Ambroise Pare Hopital ( Site 2503), Boulogne, Hauts-de-Seine, France
Hôpital Beaujon ( Site 2524), Clichy, Ile-de-France, France
Groupe hospitalier Paris saint Joseph-Service de Pneumologie-Allergologie -Oncologie Thoracique ( Si, Paris, Ile-de-France, France
Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 2525), Rennes, Ille-et-Vilaine, France
Hopital Trousseau ( Site 2512), Chambray-les-Tours, Indre-et-Loire, France
C.H.U. de Tours - Hopital Bretonneau ( Site 2515), Tours, Indre-et-Loire, France
Institut de Cancérologie de l'Ouest-Oncologie Médicale ( Site 2522), Saint Herblain, Loire-Atlantique, France
Institut de Cancérologie de Lorraine Alexis Vautrin ( Site 2532), Vandoeuvre-lès-Nancy, Lorraine, France
CHRU Lille Hospital Claude Huriez ( Site 2506), Lille, Nord, France
Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne-ONCOLOGY ( Site 2542), Clermont-Ferrand, Puy-de-Dome, France
CH Lyon Sud Hospices Civils de Lyon ( Site 2521), Pierre Benite, Rhone-Alpes, France
C.H.U. Pontchaillou ( Site 2511), Pierre Benite, Rhone, France
Centre Hospitalier du Mans-Pneumologie ( Site 2527), Le Mans, Sarthe, France
Hôpital Avicenne-Dermatologie ( Site 2538), Bobigny, Seine-Saint-Denis, France
Centre Hopitalier Intercommunal Creteil ( Site 2514), Creteil, Val-de-Marne, France
Hôpital Universitaire Paul Brousse ( Site 2541), Villejuif, Val-de-Marne, France
Institut Gustave Roussy ( Site 2513), Villejuif, Val-de-Marne, France
Hopital Cochin ( Site 2509), Paris, , France
Hopital Saint Louis ( Site 2510), Paris, , France
CHU Hopital Saint Antoine ( Site 2517), Paris, , France
Hôpital Tenon ( Site 2530), Paris, , France
Universitaetsklinikum Tuebingen ( Site 2405), Tuebingen, Baden-Wurttemberg, Germany
Universitätsklinikum Erlangen ( Site 2408), Erlangen, Bayern, Germany
Universitaetsklinik Muenchen ( Site 2406), Muenchen, Bayern, Germany
Krankenhaus Nordwest ( Site 2409), Frankfurt, Hessen, Germany
Elbe Klinikum Buxtehude ( Site 2400), Buxtehude, Niedersachsen, Germany
Medizinische Hochschule Hannover ( Site 2402), Hannover, Niedersachsen, Germany
Universitaetsklinikum Essen ( Site 2404), Essen, Nordrhein-Westfalen, Germany
Universitaetsklinikum des Saarlandes-Klinik für Innere Medizin V-Pneumologie, Allergologie, Beatmun, Homburg, Saarland, Germany
Universitatsklinikum Carl Gustav Carus ( Site 2407), Dresden, Sachsen, Germany
LungenClinic Grosshansdorf GmbH ( Site 2412), Grosshansdorf, Schleswig-Holstein, Germany
SRH Wald-Klinikum Gera GmbH ( Site 2403), Gera, Thuringen, Germany
Helios Klinikum Emil von Behring Berlin-Zehlendorf-Lungenklinik Heckeshorn ( Site 2418), Berlin, , Germany
Facharztzentrum Eppendorf ( Site 2415), Hamburg, , Germany
General Hospital of Athens "Laiko"-Hematology Department ( Site 1851), Athens, Attiki, Greece
Sotiria Regional Chest Diseases Hospital of Athens ( Site 1850), Athens, Attiki, Greece
Oncomedica ( Site 3401), Guatemala, , Guatemala
Grupo Medico Angeles ( Site 3402), Guatemala, , Guatemala
MEDI-K CAYALA ( Site 3403), Guatemala, , Guatemala
Queen Mary Hospital ( Site 1902), Hksar, , Hong Kong
Queen Mary Hospital-Department of Medicine (Respiratory) ( Site 1900), Hksar, , Hong Kong
Békés Megyei Központi Kórház Pándy Kálmán Tagkórház-Megyei Onkológiai Centrum ( Site 1405), Gyula, Bekes, Hungary
Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház ( Site 1409), Miskolc, Borsod-Abauj-Zemplen, Hungary
Fejér Megyei Szent György Egyetemi Oktató Kórház-l.Pulmonologia ( Site 1407), Székesfehérvár, Fejer, Hungary
Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház ( Site 1401), Szolnok, Jasz-Nagykun-Szolnok, Hungary
Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 1411), Budapest, Pest, Hungary
Markusovszky Egyetemi Oktatokorhaz-Onkológiai Osztály ( Site 1410), Szombathely, Vas, Hungary
Farkasgyepui Tudogyogyintezet-Pulmonologia ( Site 1414), Farkasgyepu, Veszprem, Hungary
Semmelweis University-Belgyógyászati és Hematológiai Klinika ( Site 1406), Budapest, , Hungary
Orszagos Koranyi Pulmonologiai Intezet ( Site 1403), Budapest, , Hungary
Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1413), Budapest, , Hungary
Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Haematologia) ( Site 1415), Debrecen, , Hungary
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1412), Debrecen, , Hungary
Somogy Megyei Kaposi Mor Oktato Korhaz ( Site 1402), Kaposvar, , Hungary
Zala Megyei Szent Rafael Korhaz ( Site 1400), Zalaegerszeg, , Hungary
Mater Misercordiae University Hospital ( Site 1800), Dublin, Leinster, Ireland
Tallaght University Hospital ( Site 1803), Dublin, , Ireland
St. James s Hospital ( Site 1801), Dublin, , Ireland
Rambam Health Care Campus-Oncology Division ( Site 2053), Haifa, , Israel
Hadassah Ein Kerem Medical Center ( Site 2051), Jerusalem, , Israel
Rabin Medical Center ( Site 2059), Petah-Tikva, , Israel
Chaim Sheba Medical Center ( Site 2055), Ramat Gan, , Israel
Chaim Sheba Medical Center. ( Site 2052), Ramat Gan, , Israel
Sourasky Medical Center ( Site 2054), Tel Aviv, , Israel
Shamir Medical Center Assaf Harofeh ( Site 2058), Zerifin, , Israel
Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1975), Roma, Lazio, Italy
Policlinico Universitario Agostino Gemelli ( Site 1965), Roma, Lazio, Italy
Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1968), Rozzano, Milano, Italy
Ospedale San Luigi Gonzaga ( Site 1956), Orbassano, Piemonte, Italy
IRCCS CRO Aviano, Hematology/Oncology ( Site 1957), Aviano, Pordenone, Italy
Istituto di Candiolo - IRCCS ( Site 1960), Candiolo, Torino, Italy
AO Santa Maria della Misericordia-Oncology Department ( Site 1971), Perugia, Umbria, Italy
Humanitas Gavazzeni ( Site 1954), Bergamo, , Italy
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII-UOC Oncologia ( Site 1967), Bergamo, , Italy
Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1972), Brescia, , Italy
IRCCS A.O.U. San Martino - IST ( Site 1961), Genova, , Italy
Istituto Europeo di Oncologia ( Site 1952), Milano, , Italy
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 1955), Napoli, , Italy
Azienda Ospedaliero Universitaria di Parma-UO Oncologia Medica ( Site 1964), Parma, , Italy
Azienda Ospedaliera San Camillo Forlanini ( Site 1958), Roma, , Italy
ospedale le scotte-U.O.C. Immunoterapia Oncologica ( Site 1969), Siena, , Italy
Azienda Ospedaliera Santa Maria ( Site 1962), Terni, , Italy
Nagoya University Hospital ( Site 3151), Nagoya-Shi, Aichi, Japan
National Hospital Organization Nagoya Medical Center ( Site 3109), Nagoya, Aichi, Japan
Aichi Cancer Center Hospital ( Site 3101), Nagoya, Aichi, Japan
National Cancer Center Hospital East ( Site 3121), Kashiwa, Chiba, Japan
National Hospital Organization Shikoku Cancer Center ( Site 3116), Matsuyama, Ehime, Japan
Ehime University Hospital-Obstetrics and Gynecology ( Site 3158), Toon, Ehime, Japan
Kurume University Hospital ( Site 3105), Kurume, Fukuoka, Japan
National Hospital Organization Hokkaido Cancer Center ( Site 3160), Sapporo, Hokkaido, Japan
Sapporo Kosei General Hospital ( Site 3172), Sapporo, Hokkaido, Japan
Sapporo Medical University Hospital ( Site 3113), Sapporo, Hokkaido, Japan
Hokkaido University Hospital ( Site 3165), Sapporo, Hokkaido, Japan
Hyogo Cancer Center ( Site 3131), Akashi, Hyogo, Japan
National Hospital Organization Himeji Medical Center ( Site 3111), Himeji, Hyogo, Japan
Kobe City Medical Center General Hospital ( Site 3144), Kobe, Hyogo, Japan
Hyogo Medical University Hospital ( Site 3100), Nishinomiya, Hyogo, Japan
Kanazawa University Hospital ( Site 3140), Kanazawa, Ishikawa, Japan
Kagawa University Hospital ( Site 3171), Kita, Kagawa, Japan
Kitasato University Hospital ( Site 3142), Sagamihara, Kanagawa, Japan
Yokohama City University Hospital ( Site 3163), Yokohama, Kanagawa, Japan
Kanagawa cancer center ( Site 3137), Yokohama, Kanagawa, Japan
Yokosukakyosai ( Site 3150), Yokosuka, Kanagawa, Japan
Miyagi Cancer Center ( Site 3122), Natori, Miyagi, Japan
Sendai Kousei Hospital ( Site 3115), Sendai, Miyagi, Japan
Nara Medical University Hospital ( Site 3110), Kashihara, Nara, Japan
Kurashiki Central Hospital ( Site 3132), Kurashiki, Okayama, Japan
University of the Ryukyus Hospital ( Site 3155), Nishihara, Okinawa, Japan
Osaka Habikino Medical Center ( Site 3138), Habikino, Osaka, Japan
Kansai Medical University Hospital ( Site 3126), Hirakata, Osaka, Japan
Kindai University Hospital- Osakasayama Campus ( Site 3166), Osaka-sayama, Osaka, Japan
Kindai University Hospital ( Site 3102), Osakasayama, Osaka, Japan
Kindai University Hospital- Osakasayama Campus-Department of Gastroenterology and Hepatology ( Site, Osakasayama, Osaka, Japan
Osaka Rosai Hospital ( Site 3148), Sakai, Osaka, Japan
Osaka University Hospital ( Site 3168), Suita, Osaka, Japan
Osaka Medical and Pharmaceutical University Hospital ( Site 3167), Takatsuki, Osaka, Japan
Saitama Medical University International Medical Center ( Site 3118), Hidaka, Saitama, Japan
Saitama Cancer Center ( Site 3112), Kitaadachi-gun, Saitama, Japan
Dokkyo Medical University - Koshigaya Hospital ( Site 3152), Koshigaya, Saitama, Japan
Shizuoka Cancer Center ( Site 3128), Nagaizumi, Shizuoka, Japan
Jichi Medical University Hospital ( Site 3141), Shimotsuke, Tochigi, Japan
Tokyo Medical and Dental University Hospital ( Site 3149), Bunkyō, Tokyo, Japan
Japanese Foundation for Cancer Research ( Site 3146), Koto, Tokyo, Japan
Japanese Foundation for Cancer Research ( Site 3164), Koto, Tokyo, Japan
Toranomon Hospital ( Site 3134), Minato-ku, Tokyo, Japan
Toranomon Hospital ( Site 3153), Minato-ku, Tokyo, Japan
Kyorin University Hospital ( Site 3147), Mitaka-shi, Tokyo, Japan
Kyorin University Hospital ( Site 3103), Mitaka, Tokyo, Japan
Tokyo Medical University Hospital ( Site 3170), Shinjuku-ku, Tokyo, Japan
National Hospital Organization Yamaguchi Ube Medical Center ( Site 3123), Ube, Yamaguchi, Japan
Yamaguchi University Hospital ( Site 3114), Ube, Yamaguchi, Japan
Chiba Cancer Center ( Site 3117), Chiba, , Japan
National Hospital Organization Kyushu Medical Center ( Site 3136), Fukuoka, , Japan
National Hospital Organization Kyushu Cancer Center ( Site 3169), Fukuoka, , Japan
Kyushu University Hospital ( Site 3143), Fukuoka, , Japan
Gifu University Hospital ( Site 3161), Gifu, , Japan
Hiroshima City Hiroshima Citizens Hospital ( Site 3119), Hiroshima, , Japan
Hiroshima University Hospital ( Site 3154), Hiroshima, , Japan
Kochi Health Sciences Center ( Site 3145), Kochi, , Japan
Okayama University Hospital ( Site 3107), Okayama, , Japan
Osaka City General Hospital ( Site 3125), Osaka, , Japan
National Hospital Organization - Osaka National Hospital - Institute For Clinical Research ( Site 31, Osaka, , Japan
Osaka International Cancer Institute-Gynecologic Oncology ( Site 3129), Osaka, , Japan
National Cancer Center Hospital ( Site 3130), Tokyo, , Japan
St.Luke's International Hospital ( Site 3120), Tokyo, , Japan
The Jikei University Hospital-Obstetrics and Gynecology ( Site 3156), Tokyo, , Japan
Nippon Medical School Hospital ( Site 3139), Tokyo, , Japan
Tokyo Metropolitan Komagome Hospital ( Site 3133), Tokyo, , Japan
The Cancer Institute Hospital of JFCR ( Site 3108), Tokyo, , Japan
Keio University Hospital ( Site 3127), Tokyo, , Japan
Teikyo University Hospital ( Site 3104), Tokyo, , Japan
Wakayama Medical University Hospital ( Site 3124), Wakayama, , Japan
Chonnam National University Hwasun Hospital-Hemato-Oncology ( Site 0959), Hwasun, Jeonranamdo, Korea, Republic of
National Cancer Center ( Site 0955), Goyang-si, Kyonggi-do, Korea, Republic of
CHA Bundang Medical Center CHA University ( Site 0957), Seongnam si, Kyonggi-do, Korea, Republic of
Seoul National University Bundang Hospital ( Site 0951), Seongnam-si, Kyonggi-do, Korea, Republic of
Asan Medical Center ( Site 0952), Songpagu, Seoul, Korea, Republic of
Keimyung University Dongsan Hospital CRC room 1 ( Site 0960), Daegu, Taegu-Kwangyokshi, Korea, Republic of
Chungnam national university hospital-Department of Internal Medicine ( Site 0958), Daejeon, Taejon-Kwangyokshi, Korea, Republic of
Korea University Anam Hospital ( Site 0956), Seoul, , Korea, Republic of
Seoul National University Hospital ( Site 0953), Seoul, , Korea, Republic of
Severance Hospital ( Site 0954), Seoul, , Korea, Republic of
Samsung Medical Center ( Site 0950), Seoul, , Korea, Republic of
Liepjas reionl slimnca ( Site 3851), Liepaja, , Latvia
RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia-Out-patient and Day patient facility of Ch, Riga, , Latvia
Klaipeda University Hospital-Oncology chemotherapy ( Site 3302), Klaipeda, Klaipedos Miestas, Lithuania
National Cancer Institute-Chemotherapy departament with day care unit ( Site 3301), Vilnius, Vilniaus Miestas, Lithuania
Vilniaus Universiteto Ligonine Santaros Klinikos ( Site 3300), Vilnius, , Lithuania
Hospital Tengku Ampuan Afzan ( Site 0627), Kuantan, Pahang, Malaysia
Gleneagles Penang ( Site 0625), Georgetown, Pulau Pinang, Malaysia
Pantai Hospital Kuala Lumpur ( Site 0628), Kuala Lumpur, , Malaysia
University Malaya Medical Centre ( Site 0626), Kuala Lumpur, , Malaysia
INSTITUTO NACIONAL DE CANCEROLOGIA ( Site 1102), Mexico City, Distrito Federal, Mexico
Avix Investigación Clinica, S.C.-Oncology ( Site 1104), Monterrey, Nuevo Leon, Mexico
Oaxaca Site Management Organization ( Site 1106), Oaxaca de Juarez, Oaxaca, Mexico
Medical Care and Research SA de CV ( Site 1103), Merida, Yucatan, Mexico
Oncare Viaducto Napoles ( Site 1107), Cdmx, , Mexico
Radboud University Medical Center ( Site 1554), Nijmegen, Gelderland, Netherlands
Antoni van Leeuwenhoek Ziekenhuis ( Site 1551), Amsterdam, Noord-Holland, Netherlands
Amsterdam UMC, locatie VUmc ( Site 1555), Amsterdam, Noord-Holland, Netherlands
Erasmus MC ( Site 1553), Rotterdam, Zuid-Holland, Netherlands
Universitair Medisch Centrum Groningen ( Site 1550), Groningen, , Netherlands
Canterbury Regional Cancer & Blood Service ( Site 1500), Christchurch, Canterbury, New Zealand
Waikato Hospital ( Site 1502), Hamilton, Waikato, New Zealand
Auckland City Hospital ( Site 1503), Auckland, , New Zealand
Capital & Coast District Health Board - Wellington Hospital ( Site 1501), Wellington, , New Zealand
Helse Bergen Haukeland universitetssykehus ( Site 1451), Bergen, Vestfold, Norway
Oslo Universitetssykehus Radiumhospitalet ( Site 1450), Oslo, , Norway
Oslo Universitetssykehus Ullevål-Avdeling for kreftbehandling, Ullevål ( Site 1452), Oslo, , Norway
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0678), Lima, , Peru
Hospital Cayetano Heredia-Oncology ( Site 0675), Lima, , Peru
Makati Medical Center ( Site 1702), Makati, National Capital Region, Philippines
Lung Center of the Philippines ( Site 1705), Quezon City, National Capital Region, Philippines
St. Luke s Medical Center ( Site 1700), Quezon City, National Capital Region, Philippines
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1612), Bydgoszcz, Kujawsko-pomorskie, Poland
Powiatowe Centrum Zdrowia w Brzezinach Sp. z o. o. Oddział Dziennej Chemioterapii ( Site 1611), Brzeziny, Lodzkie, Poland
Instytut Centrum Zdrowia Matki Polki-Klinika Onkologii ( Site 1609), Łódź, Lodzkie, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Oddzial w Krakowie ( Site 1608), Krakow, Malopolskie, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie (, Warszawa, Mazowieckie, Poland
Wojskowy Instytut Medyczny-Klinika Onkologii ( Site 1606), Warszawa, Mazowieckie, Poland
Opolskie Centrum Onkologii w Opolu im. prof. Tadeusza Kosza-Klinika Onkologii z Odcinkiem Dziennym, Opole, Opolskie, Poland
Bialostockie Centrum Onkologii ( Site 1610), Bialystok, Podlaskie, Poland
Przychodnia Lekarska KOMED ( Site 1603), Konin, Wielkopolskie, Poland
Med-Polonia Sp. z o. o. ( Site 1605), Poznan, Wielkopolskie, Poland
Szpital Kliniczny im. Przemienienia Panskiego Uniwersytetu Medycznego im. K. Marcinkowskiego w Pozna, Poznan, Wielkopolskie, Poland
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1614), Koszalin, Zachodniopomorskie, Poland
Champalimaud Foundation ( Site 1751), Lisbon, Lisboa, Portugal
Centro Hospitalar Lisboa Norte E.P.E. - Hospital Pulido Valente ( Site 1750), Lisboa, , Portugal
Instituto Português de Oncologia do Porto Francisco Gentil, EPE-Oncologia Médica ( Site 1753), Porto, , Portugal
Centro Hospitalar de Sao Joao - Hospital de Sao Joao ( Site 1752), Porto, , Portugal
Ad-Vance Medical Research-Research ( Site 1151), Ponce, , Puerto Rico
FDI Clinical Research ( Site 1152), San Juan, , Puerto Rico
UPR Comprehensive Cancer Center ( Site 1150), San Juan, , Puerto Rico
Spitalul Județean Sfântul Ioan cel Nou Suceava-Oncology ( Site 3550), Suceava, , Romania
Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 1204), Ufa, Baskortostan, Respublika, Russian Federation
Bashkir State Medical University ( Site 1221), Ufa, Baskortostan, Respublika, Russian Federation
Belgorod Oncology Dispensary ( Site 1213), Belgorod, Belgorodskaya Oblast, Russian Federation
Regional Budgetary Healthcare Institution 'Ivanovo Regional Oncology Dispensary'-Urology ( Site 1219, Ivanovo, Ivanovskaya Oblast, Russian Federation
GBUZ LOKB ( Site 1218), Saint-Petersburg, Leningradskaya Oblast, Russian Federation
GBUZ LOKB-Oncology department #1 ( Site 1222), Saint-Petersburg, Leningradskaya Oblast, Russian Federation
Ogarev Mordovia State University ( Site 1206), Saransk, Mordoviya, Respublika, Russian Federation
The National Medico-Surgical Center N.I. Pirogov ( Site 1225), Moscow, Moskva, Russian Federation
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 1201), Moscow, Moskva, Russian Federation
N.N. Blokhin NMRCO ( Site 1209), Moscow, Moskva, Russian Federation
Russian Scientific Center of Roentgenoradiology ( Site 1215), Moscow, Moskva, Russian Federation
P. A. Hertsen Moscow Oncology Research Center ( Site 1214), Moscow, Moskva, Russian Federation
FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 1208), Moscow, Moskva, Russian Federation
Russian Scientific Research Institute of Hematology and Blood Transfusion-Hematology ( Site 1224), Saint Petersburg, Sankt-Peterburg, Russian Federation
N.N.Petrov Research Institute of Oncology-Department of Preclinical and Clinical Research ( Site 121, Saint Petersburg, Sankt-Peterburg, Russian Federation
Clinical Research Center of specialized types medical care-Oncology ( Site 1205), Saint-Petersburg, Sankt-Peterburg, Russian Federation
GBUZ SK Pyatigorsk Interdistrict Oncology dispensary ( Site 1223), Pyatigorsk, Stavropol Skiy Kray, Russian Federation
Republican Clinical Oncology Dispensary ( Site 1228), Kazan, Tatarstan, Respublika, Russian Federation
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1203), Kazan, Tatarstan, Respublika, Russian Federation
Tomsk Scientific Research Institute of Oncology ( Site 1227), Tomsk, Tomskaya Oblast, Russian Federation
SAIH of the Tyumen region, Multidisciplinary Clinical Medical Center "Medical town" ( Site 1220), Tyumen, Tyumenskaya Oblast, Russian Federation
Udmurtian Republican Clinical Oncology Center ( Site 1212), Izhevsk, Udmurtskaya Respublika, Russian Federation
National Cancer Centre Singapore ( Site 2200), Singapore, Central Singapore, Singapore
National University Hospital-Haematology -Oncology Research Group ( Site 2201), Singapore, South West, Singapore
Wits Clinical Research ( Site 2002), Johannesburg, Gauteng, South Africa
Wilgers Oncology Centre ( Site 2006), Pretoria, Gauteng, South Africa
LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 2005), Pretoria, Gauteng, South Africa
Sandton Oncology Medical Group (Pty) Ltd-Research ( Site 2004), Sandton, Gauteng, South Africa
The Oncology Centre ( Site 2000), Durban, Limpopo, South Africa
Cape Town Oncology Trials ( Site 2007), Cape Town, Western Cape, South Africa
GVI Oncology ( Site 2008), George, Western Cape, South Africa
Hospital Universitario Virgen de la Victoria ( Site 0878), Malaga, Andalucia, Spain
Hospital Universitario Central de Asturias-Medical Oncology ( Site 0870), Oviedo, Asturias, Spain
Hospital Universitari Son Espases-Oncologia ( Site 0883), Palma, Baleares, Spain
Instituto Catalan de Oncologia ICO - Hospital Duran i Reynals ( Site 0860), Hospitalet de Llobregat, Barcelona, Spain
H. Marques de Valdecilla ( Site 0865), Santander, Cantabria, Spain
Hospital Clinic de Barcelona ( Site 0852), Barcelona, Cataluna, Spain
Hospital de la Santa Creu i Sant Pau-Oncología Médica ( Site 0862), Barcelona, Cataluna, Spain
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0876), Santiago de Compostela, La Coruna, Spain
Hospital Universitario Insular de Gran Canaria ( Site 0867), Las Palmas de Gran Canaria, Las Palmas, Spain
Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 0877), Madrid, Madrid, Comunidad De, Spain
Hospital Universitario Puerta de Hierro-Majadahonda ( Site 0861), Majadahonda, Madrid, Spain
Hospital Universitario Quiron Madrid ( Site 0868), Pozuelo de Alarcon, Madrid, Spain
H.R.U Malaga - Hospital General ( Site 0884), Málaga, Malaga, Spain
Hospital Universitari Sant Joan de Reus-Oncology ( Site 0874), Reus, Tarragona, Spain
Instituto Valenciano de Oncologia - IVO ( Site 0863), Valencia, Valenciana, Comunitat, Spain
Hospital Clinico de Valencia ( Site 0858), Valencia, Valenciana, Comunitat, Spain
Hospital General Universitario de Valencia ( Site 0854), Valencia, Valenciana, Comunitat, Spain
Hospital Arnau de Vilanova ( Site 0866), Valencia, Valenciana, Comunitat, Spain
Hospital Universitari i Politecnic La Fe ( Site 0875), València, Valencia, Spain
Hospital General Universitario de Alicante-Oncologia ( Site 0881), Alicante, , Spain
Parc de Salut Mar - Hospital del Mar-Oncologia ( Site 0873), Barcelona, , Spain
H.U. Vall de Hebron ( Site 0850), Barcelona, , Spain
Institut Catala d Oncologia Hospital Germans Trias i Pujol ( Site 0851), Barcelona, , Spain
Complejo Hospitalario de Jaén-Servicio de Oncología Médica ( Site 0879), Jaen, , Spain
Hospital Universitario Gregorio Maranon ( Site 0864), Madrid, , Spain
Clinica Universitaria de Navarra ( Site 0855), Madrid, , Spain
Hospital Clinico San Carlos ( Site 0857), Madrid, , Spain
Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 0871), Madrid, , Spain
Hospital General Universitario 12 de Octubre ( Site 0856), Madrid, , Spain
Hospital Universitario La Paz ( Site 0853), Madrid, , Spain
Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid, ( Site 0, Madrid, , Spain
Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 0880), Sevilla, , Spain
HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 0872), Sevilla, , Spain
Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 0882), Sevilla, , Spain
Hospital Clinico Universitario Lozano Blesa ( Site 0859), Zaragoza, , Spain
Karolinska Universitetssjukhuset Solna ( Site 0802), Stockholm, Stockholms Lan, Sweden
Blod och Tumorssjukdomar. Akademiska sjukhuset ( Site 0801), Uppsala, Uppsala Lan, Sweden
Norrlands Universitetssjukhus ( Site 0800), Umea, Vasterbottens Lan, Sweden
Sahlgrenska Universitetssjukhuset-Department of Oncology CTU Clinical Trial Unit ( Site 0803), Gothenburg, Vastra Gotalands Lan, Sweden
University Hospital Basel ( Site 0752), Basel, Basel-Stadt, Switzerland
Hôpitaux Universitaires de Genève (HUG) ( Site 0753), Genève, Geneve, Switzerland
Universitaetsspital Zuerich ( Site 0750), Zürich-Flughafen, Zurich, Switzerland
Kaohsiung Chang Gung Memorial Hospital ( Site 3203), Kaohsiung, , Taiwan
China Medical University Hospital ( Site 3204), Taichung, , Taiwan
National Cheng Kung University Hospital ( Site 3201), Tainan, , Taiwan
National Taiwan University Hospital ( Site 3200), Taipei, , Taiwan
Mackay Memorial Hospital ( Site 3205), Taipei, , Taiwan
Taipei Veterans General Hospital ( Site 3202), Taipei, , Taiwan
Koo Foundation Sun Yat-Sen Cancer Center-Gynecology, Obstetrics, and women's health ( Site 3207), Taipei, , Taiwan
Chang Gung Medical Foundation-Linkou Branch ( Site 3206), Taoyuan, , Taiwan
Chulalongkorn University ( Site 2363), Bangkok, Krung Thep Maha Nakhon, Thailand
Ramathibodi Hospital ( Site 2364), Bangkok, Krung Thep Maha Nakhon, Thailand
Faculty of Medicine Siriraj Hospital ( Site 2365), Bangkok, Krung Thep Maha Nakhon, Thailand
Acibadem Altunizade Hospital-Oncology ( Site 1317), Üsküdar /Istanbul, Istanbul, Turkey
Acibadem Adana Hospital-Pediatric Hematology-Oncology ( Site 1312), Adana, , Turkey
Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1307), Adana, , Turkey
Ankara University Hospital Cebeci ( Site 1306), Ankara, , Turkey
Hacettepe Universitesi-oncology hospital ( Site 1304), Ankara, , Turkey
Ankara City Hospital-Medical Oncology ( Site 1311), Ankara, , Turkey
Baskent Universitesi Ankara Hastanesi ( Site 1303), Ankara, , Turkey
Memorial Antalya Hospital-Oncology ( Site 1315), Antalya, , Turkey
Trakya Universitesi Tip Fakultesi ( Site 1301), Edirne, , Turkey
Bezmialem Vakf Üniversitesi-Oncology ( Site 1308), Istanbul, , Turkey
Istanbul University Capa Campus ( Site 1314), Istanbul, , Turkey
Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1302), Istanbul, , Turkey
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1316), Istanbul, , Turkey
Marmara Universitesi Pendik Egitim Arastirma Hastanesi-Medical Oncology ( Site 1305), Istanbul, , Turkey
Ege Universitesi Tip Fakultesi Hastanesi ( Site 1300), Izmir, , Turkey
I.E.U. Medical Point Hastanesi-Oncology ( Site 1310), Izmir, , Turkey
Kocaeli Üniversitesi ( Site 1313), Kocaeli, , Turkey
Inonu Universitesi ( Site 1309), Malatya, , Turkey
Municipal Non-profit Enterprise "City Clinical Hospital #4" of Dnipro City Council ( Site 3650), Dnipro, Dnipropetrovska Oblast, Ukraine
MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional-Chemotherapy department ( Site 3657), Kryvyi Rih, Dnipropetrovska Oblast, Ukraine
Communal Non-Commercial Enterprise "Prykarpatski Clinical Oncological Center" of Ivano-Frankivsk Reg, Ivano-Frankivsk, Ivano-Frankivska Oblast, Ukraine
MNPE Regional Center of Oncology ( Site 3665), Kharkiv, Kharkivska Oblast, Ukraine
Private Enterprise Private Manufacturing Company Acinus-Medical and Diagnostic Centre ( Site 3656), Kropyvnytskyi, Kirovohradska Oblast, Ukraine
National Cancer Institute-Department of Minimally Invasive and Endoscopic Surgery, Interventional R, Kyiv, Kyivska Oblast, Ukraine
Municipal non-profit enterprise "Kyiv City Clinical Oncology Center" of executive body of Kyiv City, Kyiv, Kyivska Oblast, Ukraine
Municipal institution of Lviv regional council Lviv Oncology-Chemotherapy ( Site 3653), Lviv, Lvivska Oblast, Ukraine
Odessa Regional Oncology Center ( Site 3655), Odessa, Odeska Oblast, Ukraine
Sumy regional clinical oncological dispensary-Oncothoracic department ( Site 3661), Sumy, Sumska Oblast, Ukraine
Communal Noncommercial Enterprise "Podillia Regional Oncology Center Of Vinnytsia Regional Council", Vinnytsia, Vinnytska Oblast, Ukraine
Transcarpathian Regional Clinical Oncology Center-Chemotherapy dept. ( Site 3652), Uzhhorod, Zakarpatska Oblast, Ukraine
Municipal non-profit enterprise "Zaporizhzhia Regional Antitumor Center" Zaporizhzhya Regional Counc, Zaporizhia, Zaporizka Oblast, Ukraine
Aberdeen Royal Infirmary-Department of Oncology ( Site 0521), Aberdeen, Aberdeen City, United Kingdom
Western General Hospital ( Site 0502), Edinburgh, Edinburgh, City Of, United Kingdom
The Christie ( Site 0516), Manchester, England, United Kingdom
Weston Park Hospital ( Site 0519), Sheffield, England, United Kingdom
Mid Essex Hospitals Service Trust. Broomfield Hospital ( Site 0503), Broomfield, Essex, United Kingdom
The Beatson West of Scotland Cancer Centre ( Site 0506), Glasgow, Glasgow City, United Kingdom
Royal Preston Hospital ( Site 0518), Preston, Lancashire, United Kingdom
Barts Health NHS Trust ( Site 0512), London, London, City Of, United Kingdom
University College London Hospital-Cancer Clinical Trials Unit ( Site 0520), London, London, City Of, United Kingdom
Royal Free Hospital ( Site 0507), London, London, City Of, United Kingdom
Royal Marsden Hospital ( Site 0505), London, London, City Of, United Kingdom
Sarah Cannon Research UK ( Site 0504), London, London, City Of, United Kingdom
Belfast City Hospital ( Site 0508), Belfast, Northern Ireland, United Kingdom
Nottingham University Hospitals NHS Trust ( Site 0510), Nottingham, Nottinghamshire, United Kingdom
St James University Hospital ( Site 0509), Leeds, , United Kingdom
The Royal Marsden NHS Foundation Trust. ( Site 0513), Sutton, , United Kingdom
New Cross Hospital-Department of Oncology ( Site 0517), Wolverhampton, , United Kingdom
Contact Details
Name: Medical Director
Affiliation: Merck Sharp & Dohme LLC
Role: STUDY_DIRECTOR
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