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Brief Title: Dose-escalation Study of Gimatecan Administered in Two Different Schedules in Adult Patients With Advanced Solid Tumors
Official Title: A Phase I Open-label, Multi-center Dose-escalation Study to Determine the Maximum Tolerated Dose (MTD) and Dose Limiting Toxicity of Gimatecan Administered in Two Different Schedules in Adult Patients With Advanced Solid Tumors
Study ID: NCT00420485
Brief Summary: This study will evaluate the Maximum Tolerated Dose and dose limiting toxicity of gimatecan administered orally in patients with advanced solid tumors
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Novartis Investigative Site, Vancouver, British Columbia, Canada
MD Anderson Cancer Center - Orlando, Toronto, Ontario, Canada
Novartis Investigative Site, Copenhagen, , Denmark
Novartis Investigative Site, Dijon Cedex, , France
Novartis Investigative Site, Paris, , France
Novartis Investigative Site, Saint-Herblain Cedex, , France
Novartis Investigative Site, Toulouse, , France
Novartis Investigative Site, Mainz, , Germany
Novartis Investigative Site, Tubingen, , Germany
Novartis Investigative Site, Enschede, , Netherlands
Novartis Investigative Site, Oslo, , Norway
Novartis Investigative Site, Madrid, , Spain
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR