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Brief Title: LBH589, Paclitaxel, Carboplatin +/- Bevacizumab for Solid Tumors
Official Title: A Phase I Study of LBH589 in Combination With Paclitaxel and Carboplatin +/- Bevacizumab the Treatment of Solid Tumors
Study ID: NCT00556088
Brief Summary: This phase I protocol will evaluate the safety and tolerability of the combination of LBH589 and paclitaxel/carboplatin. The combination of LBH589, paclitaxel/carboplatin, and bevacizumab will also be evaluated for tolerability and preliminary antitumor activity in a subset of patients with advanced non-small cell lung cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Name: Howard A. Burris, M.D.
Affiliation: SCRI Development Innovations, LLC
Role: STUDY_CHAIR