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Brief Title: Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors
Official Title: A Phase I Open-label Study of the Safety, Tolerability, and Pharmacokinetics of Two Schedules of Oral Topotecan in Combination With Pazopanib in Subjects With Advanced Solid Tumors
Study ID: NCT00732420
Brief Summary: To determined what dose of topotecan can be safely given with daily pazopanib.
Detailed Description: A Phase I Open-label Study of the Safety, Tolerability, and Pharmacokinetics of Two Schedules of Oral Topotecan in combination with Pazopanib in Subjects with Advanced Solid Tumors
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GSK Investigational Site, Philadelphia, Pennsylvania, United States
GSK Investigational Site, Amsterdam, , Netherlands
GSK Investigational Site, Utrecht, , Netherlands
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR