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Spots Global Cancer Trial Database for A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)

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Trial Identification

Brief Title: A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)

Official Title: A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy (POD1UM-202)

Study ID: NCT03597295

Interventions

Retifanlimab

Study Description

Brief Summary: The purpose of this study is to assess the efficacy of INCMGA00012 in participants with locally advanced or metastatic squamous carcinoma of the anal canal (SCAC) who have progressed after platinum-based chemotherapy.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

City of Hope National Medical Center, Duarte, California, United States

UC Davis Comprehensive Cancer Center, Sacramento, California, United States

Ridley-Tree Cancer Center, Santa Barbara, California, United States

Maryland Oncology Hematology P.A., Rockville, Maryland, United States

Texas Oncology-Baylor Charles A. Sammons, Dallas, Texas, United States

Texas Oncology-McKinney, McKinney, Texas, United States

Renovatio Clinical, Spring, Texas, United States

Zna Middelheim, Antwerp, , Belgium

Hopital Erasme, Brussels, , Belgium

Aarhus Universitets Hospital, Aarhus, , Denmark

Herlev Og Gentofte Hospital, Herlev, , Denmark

Vejle Hospital, Vejle, , Denmark

Centre Hospitalier Universitaire de Besancon, Besancon, , France

Chu Hopital de La Timone, Marseille Cedex 5, , France

CHU Hopital De La Timone, Marseille, , France

Icm Montpellier, Montpellier Cedex 5, , France

Hopital Universitaire Pitie-Salpetriere, Paris, , France

Chu de Rennes - Hôpital Pontchaillou, Rennes Cedex 9, , France

Centre de Lutte Contre Le Cancer - Institut de Cancerologie de L'Ouest - Rene Gauducheau, Saint Herblain Cedex, , France

CHU Toulouse Hopital Rangueil, Toulouse, , France

University Medical Centre Hamburg-Eppendorf, Centre of Oncology, Hamburg, , Germany

Asklepios Klinik Altona, Hamburg, , Germany

Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, , Italy

Ospedale A. Perrino - Brindisi, Brindisi, , Italy

A.O.U. Policlinico V. Emanuele G. Rodolico, Catania, , Italy

Ospedale Degli Infermi - Faenza, Faenza, , Italy

Irccs Azienda Ospedaliera Universitaria San Martino, Genova, , Italy

Niguarda Cancer Center, Milano, , Italy

Aou Modena - Policlinico, Modena, , Italy

Clinica La Maddalena, Palermo, , Italy

Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore, Rome, , Italy

IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo, , Italy

Haukeland U Hospital Bergen, Bergen, , Norway

Oslo U, Oslo, , Norway

Hospital General Universitari Vall D Hebron, Barcelona, , Spain

Hospital Clinic I Provincial, Barcelona, , Spain

Hospital Universitario 12 de Octubre, Madrid, , Spain

Royal Sussex County Hospital, Brighton, , United Kingdom

Royal Marsden Hospital, Chelsea, , United Kingdom

Castle Hill Hospital, Cottingham, , United Kingdom

St. James U Hospital, Leeds, , United Kingdom

St. James Univ Hospital, Leeds, , United Kingdom

Royal Free London Nhs Foundation Trust, London, , United Kingdom

The Royal Marsden Nhs Foundation Trust - Chelsea, London, , United Kingdom

The Christie NHS Foundation Trust, Manchester, , United Kingdom

Royal Marsden Hospital, Sutton, , United Kingdom

Royal Cornwall Hospital, Sunrise Centre, Truro, , United Kingdom

Contact Details

Name: Incyte Medical Monitor

Affiliation: Incyte Corporation

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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