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Brief Title: A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)
Official Title: A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy (POD1UM-202)
Study ID: NCT03597295
Brief Summary: The purpose of this study is to assess the efficacy of INCMGA00012 in participants with locally advanced or metastatic squamous carcinoma of the anal canal (SCAC) who have progressed after platinum-based chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
City of Hope National Medical Center, Duarte, California, United States
UC Davis Comprehensive Cancer Center, Sacramento, California, United States
Ridley-Tree Cancer Center, Santa Barbara, California, United States
Maryland Oncology Hematology P.A., Rockville, Maryland, United States
Texas Oncology-Baylor Charles A. Sammons, Dallas, Texas, United States
Texas Oncology-McKinney, McKinney, Texas, United States
Renovatio Clinical, Spring, Texas, United States
Zna Middelheim, Antwerp, , Belgium
Hopital Erasme, Brussels, , Belgium
Aarhus Universitets Hospital, Aarhus, , Denmark
Herlev Og Gentofte Hospital, Herlev, , Denmark
Vejle Hospital, Vejle, , Denmark
Centre Hospitalier Universitaire de Besancon, Besancon, , France
Chu Hopital de La Timone, Marseille Cedex 5, , France
CHU Hopital De La Timone, Marseille, , France
Icm Montpellier, Montpellier Cedex 5, , France
Hopital Universitaire Pitie-Salpetriere, Paris, , France
Chu de Rennes - Hôpital Pontchaillou, Rennes Cedex 9, , France
Centre de Lutte Contre Le Cancer - Institut de Cancerologie de L'Ouest - Rene Gauducheau, Saint Herblain Cedex, , France
CHU Toulouse Hopital Rangueil, Toulouse, , France
University Medical Centre Hamburg-Eppendorf, Centre of Oncology, Hamburg, , Germany
Asklepios Klinik Altona, Hamburg, , Germany
Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, , Italy
Ospedale A. Perrino - Brindisi, Brindisi, , Italy
A.O.U. Policlinico V. Emanuele G. Rodolico, Catania, , Italy
Ospedale Degli Infermi - Faenza, Faenza, , Italy
Irccs Azienda Ospedaliera Universitaria San Martino, Genova, , Italy
Niguarda Cancer Center, Milano, , Italy
Aou Modena - Policlinico, Modena, , Italy
Clinica La Maddalena, Palermo, , Italy
Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore, Rome, , Italy
IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo, , Italy
Haukeland U Hospital Bergen, Bergen, , Norway
Oslo U, Oslo, , Norway
Hospital General Universitari Vall D Hebron, Barcelona, , Spain
Hospital Clinic I Provincial, Barcelona, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Royal Sussex County Hospital, Brighton, , United Kingdom
Royal Marsden Hospital, Chelsea, , United Kingdom
Castle Hill Hospital, Cottingham, , United Kingdom
St. James U Hospital, Leeds, , United Kingdom
St. James Univ Hospital, Leeds, , United Kingdom
Royal Free London Nhs Foundation Trust, London, , United Kingdom
The Royal Marsden Nhs Foundation Trust - Chelsea, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
Royal Marsden Hospital, Sutton, , United Kingdom
Royal Cornwall Hospital, Sunrise Centre, Truro, , United Kingdom
Name: Incyte Medical Monitor
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR