Spots Global Cancer Trial Database for MicroRNA Markers in Head and Neck Cancers

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Trial Identification

Brief Title: MicroRNA Markers in Head and Neck Cancers

Official Title: MicroRNA Markers in Head and Neck Cancers

Study ID: NCT04305366

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

Tissue collection

Study Description

Brief Summary: The purpose of this study is to investigate the presence of miRNA markers in saliva, blood, FNA and tissue specimens in patients with and without head and neck cancer and evaluate whether these miRNA markers can provide prognostic or diagnostic clinical significance in the treatment of head and neck cancer patients.

Detailed Description: Micro RNA (miRNA) markers were initially discovered in 1993 and recent research has shown that they have great potential for use as both surveillance and prognostic markers in cancer treatment, as well as potential targets for cancer therapy. Recent research has identified several miRNA markers which appear to be potential markers for head and neck squamous cell carcinoma, and these have been tested in both mouse and human banked tumor samples. These investigators hypothesize that these markers may also be present in other tissues, including fine needle aspiration biopsy, blood, and saliva specimens, and will be sensitive and specific to patients with known head and neck cancer.