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Brief Title: Nivolumab for Treatment of Squamous Cell Carcinoma of the Skin
Official Title: Phase II Study of Nivolumab (Group 1) and Nivolumab Plus Relatlimab (Group 2) in Patients With Locally Advanced/ Metastatic Squamous Cell Carcinoma of the Skin
Study ID: NCT04204837
Brief Summary: To determine the Objective Response Rate (ORR) of immunotherapy with Nivolumab (Group 1) and Nivolumab plus Relatlimab (Group 2) in patients with locally advanced/metastatic squamous cell carcinoma of the skin using Response Criteria in Solid Tumors Version 1.1 (RECIST1.1) per site assessment (Time Frame Group 2: From first dose up to 5 years)
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Universitätsklinikum Graz - LKH, Klinische Abteilung für Onkologie, Graz, , Austria
LKH Innsbruck Universitätsklinik für Dermatologie und Venerologie, Innsbruck, , Austria
Klinikum Klagenfurt am Wörthersee, Klagenfurt, , Austria
Universitätsklinik für Dermatologie und Allergologie der Paracelsus medizinischen Privatuniversität Salzburg, Salzburg, , Austria
Abteilung für Haut- und Geschlechtskrankheiten, Universitätsklinikum St. Pölten Karl Landsteiner Privatuniversität für Gesundheitswissenschaften, St.Pölten, , Austria
Med Uni Wien, Univ. Klinik für Dermatologie, Vienna, , Austria
Klinikum Wels-Grieskirchen GmbH, Wels, , Austria
Name: Martin Laimer, MD
Affiliation: Salzburger Landeskliniken
Role: PRINCIPAL_INVESTIGATOR