Spots Global Cancer Trial Database for Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

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Trial Identification

Brief Title: Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Official Title: Prospective Evaluation of Esophageal Pathology Treatment of Head and Neck Carcinoma

Study ID: NCT01164566

Conditions

Stage I Adenoid Cystic Carcinoma of the Oral Cavity

Stage I Mucoepidermoid Carcinoma of the Oral Cavity

Stage I Squamous Cell Carcinoma of the Hypopharynx

Stage I Squamous Cell Carcinoma of the Larynx

Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity

Stage I Verrucous Carcinoma of the Larynx

Stage I Verrucous Carcinoma of the Oral Cavity

Stage II Adenoid Cystic Carcinoma of the Oral Cavity

Stage II Mucoepidermoid Carcinoma of the Oral Cavity

Stage II Squamous Cell Carcinoma of the Hypopharynx

Stage II Squamous Cell Carcinoma of the Larynx

Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity

Stage II Verrucous Carcinoma of the Larynx

Stage II Verrucous Carcinoma of the Oral Cavity

Stage III Adenoid Cystic Carcinoma of the Oral Cavity

Stage III Mucoepidermoid Carcinoma of the Oral Cavity

Stage III Squamous Cell Carcinoma of the Hypopharynx

Stage III Squamous Cell Carcinoma of the Larynx

Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity

Stage III Verrucous Carcinoma of the Larynx

Stage III Verrucous Carcinoma of the Oral Cavity

Stage IV Adenoid Cystic Carcinoma of the Oral Cavity

Stage IV Mucoepidermoid Carcinoma of the Oral Cavity

Stage IV Squamous Cell Carcinoma of the Hypopharynx

Stage IV Squamous Cell Carcinoma of the Larynx

Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity

Stage IV Verrucous Carcinoma of the Larynx

Stage IV Verrucous Carcinoma of the Oral Cavity

Interventions

endoscopic procedure

questionnaire administration

Study Description

Brief Summary: Brief Summary: RATIONALE: Comparing results of diagnostic procedures, such as esophagoscopy, done before and after radiation therapy and/or chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment. PURPOSE: This clinical trial is studying esophagoscopy in evaluating treatment in patients with stage I-IV head and neck cancer who are undergoing radiation therapy and/or chemotherapy.

Detailed Description: OBJECTIVES: I. To assess the prevalence of esophageal pathology (any esophageal abnormality, specifically: esophagitis, stricture/web, infections, neoplasms) as identified by esophagoscopy in patients with HNCA before and 3 months following primary radiation and/or chemotherapy. II. To assess the changes in self-reported dysphagia symptoms as measured by the Eating Assessment Tool. OUTLINE: Patients undergo transnasal esophagoscopy at baseline and 3 months following completion of radiation therapy and/or chemotherapy.