Spots Global Cancer Trial Database for Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC
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Trial Identification
Brief Title: Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC
Official Title: A Phase 2 Open-label, Multicenter, Randomized, Multidrug Platform Study of Durvalumab (MEDI4736) Alone or in Combination With Novel Agents in Subjects With Locally Advanced, Unresectable (Stage III) Non-small Cell Lung Cancer (COAST)
Study ID: NCT03822351
Study Description
Brief Summary: The purpose of this study is to compare the clinical activity of durvalumab alone vs durvalumab in combination with novel agents. The overall study goal is early identification of novel durvalumab combinations that are more active than durvalumab alone in the treatment of patients with unresectable, Stage III NSCLC who have not progressed after cCRT.
Detailed Description: Study D9108C00001 (COAST) is a Phase 2, open-label, multicenter, randomized multidrug platform study assessing the efficacy and safety of durvalumab alone vs durvalumab in combination with novel agents in subjects with locally advanced, unresectable, Stage III non-small cell lung cancer (NSCLC).
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Anaheim, California, United States
Research Site, Duarte, California, United States
Research Site, Sacramento, California, United States
Research Site, New Haven, Connecticut, United States
Research Site, West Haven, Connecticut, United States
Research Site, Washington, District of Columbia, United States
Research Site, Orlando, Florida, United States
Research Site, Winter Haven, Florida, United States
Research Site, Wichita, Kansas, United States
Research Site, Lexington, Kentucky, United States
Research Site, Louisville, Kentucky, United States
Research Site, Baton Rouge, Louisiana, United States
Research Site, Covington, Louisiana, United States
Research Site, Rosedale, Maryland, United States
Research Site, Lincoln, Nebraska, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Portland, Oregon, United States
Research Site, Gettysburg, Pennsylvania, United States
Research Site, Lancaster, Pennsylvania, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Sioux Falls, South Dakota, United States
Research Site, Germantown, Tennessee, United States
Research Site, Memphis, Tennessee, United States
Research Site, Tyler, Texas, United States
Research Site, Salt Lake City, Utah, United States
Research Site, Richmond, Virginia, United States
Research Site, Tacoma, Washington, United States
Research Site, Edmonton, Alberta, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Bordeaux Cedex, , France
Research Site, Brest, , France
Research Site, Bron, , France
Research Site, Creteil, , France
Research Site, La Rochelle Cedex, , France
Research Site, Lille, , France
Research Site, Limoges Cedex, , France
Research Site, Lyon Cedex 04, , France
Research Site, Marseille Cedex 20, , France
Research Site, Nice, , France
Research Site, Pierre Benite, , France
Research Site, Rennes Cedex 9, , France
Research Site, STRASBOURG Cedex, , France
Research Site, Toulouse, , France
Research Site, Hong Kong, , Hong Kong
Research Site, Jordan, , Hong Kong
Research Site, Kowloon, , Hong Kong
Research Site, Catania, , Italy
Research Site, Cremona, , Italy
Research Site, Milano, , Italy
Research Site, Milano, , Italy
Research Site, Palermo, , Italy
Research Site, Ravenna, , Italy
Research Site, Siena, , Italy
Research Site, Gdynia, , Poland
Research Site, Lodz, , Poland
Research Site, Lodz, , Poland
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Porto, , Portugal
Research Site, Porto, , Portugal
Research Site, A Coruña, , Spain
Research Site, Badajoz, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Castelló de la Plana, , Spain
Research Site, Madrid, , Spain
Research Site, Málaga, , Spain
Research Site, Valencia, , Spain
Research Site, Chiayi, , Taiwan
Research Site, Taichung, , Taiwan
Contact Details
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