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Brief Title: Phase Ib Study of Olaparib Plus Weekly Carboplatin and Paclitaxel in Relapsed Ovarian Cancer
Official Title: Phase Ib With Expansion of Patients at the MTD Study of Olaparib Plus Weekly (Metronomic) Carboplatin and Paclitaxel in Relapsed Ovarian Cancer Patients
Study ID: NCT01650376
Brief Summary: The purpose of this study is to determine the maximum tolerated dose (MTD) of the investigational agent, olaparib, to give in combination with carboplatin and paclitaxel in patients with relapsed ovarian cancer or uterine cancer. Furthermore, the investigators intend to study the safety and tolerability of the study treatment, response to treatment, time to disease progression, and overall survival.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Swedish Cancer Institute Edmonds Campus, Edmonds, Washington, United States
Swedish Cancer Institute Issaquah Campus, Issaquah, Washington, United States
Pacific Gynecology Specialists, Seattle, Washington, United States
Swedish Medical Center Cancer Institute, Seattle, Washington, United States
Swedish Cancer Institute Ballard Campus, Seattle, Washington, United States
Name: Saul Rivkin, MD
Affiliation: Swedish Medical Center Cancer Institute
Role: PRINCIPAL_INVESTIGATOR