Spots Global Cancer Trial Database for Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination Chemotherapy
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Trial Identification
Brief Title: Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination Chemotherapy
Official Title: Randomized, Phase III, Double-Blind Placebo-Controlled Trial of Sunitinib (NSC #736511) as Maintenance Therapy in Non-progressing Patients Following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced, Stage IIIB / IV Non-small Cell Lung Cancer
Study ID: NCT00693992
Study Description
Brief Summary: This randomized phase III trial studies sunitinib malate to see how well it works when given as maintenance therapy (meaning it is approved for treatment after chemotherapy) in patients with stage IIIB-IV non-small cell lung cancer who have responded to prior treatment with combination chemotherapy. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking the growth of new blood vessels necessary for tumor growth. It is not yet known whether sunitinib malate is effective in helping tumors continue to shrink or stop growing.
Detailed Description: PRIMARY OBJECTIVES: I. To evaluate the effect of sunitinib (sunitinib malate) compared to placebo on progression-free survival (PFS) in advanced non-small cell lung cancer (NSCLC) patients who have had either stable or responding disease over the course of their initial 4 cycles of platinum-based therapy. SECONDARY OBJECTIVES: I. To evaluate the toxicity of sunitinib compared to placebo in the maintenance setting. II. To evaluate the additional response rate as a result of sunitinib in this setting. III. To assess the impact of sunitinib on overall survival compared to the placebo arm. IV. To assess the impact of sunitinib on delaying the time to deterioration in quality of life and symptom progression compared to placebo using the European Organization for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire (QLQ-C30) and Lung Cancer Module (LC13). V. To assess vascular endothelial growth factor (VEGF) haplotypes in advanced non-small cell lung cancer and sunitinib maintenance. OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients receive sunitinib malate orally (PO) once daily (QD) on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM II: Patients receive placebo PO QD on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 3 months for 1 year, every 6 months for 1 year, and then periodically for 3 years.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Northeast Alabama Regional Medical Center, Anniston, Alabama, United States
Providence Hospital, Mobile, Alabama, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Veteran's Administration Medical Center, Little Rock, Arkansas, United States
Kaiser Permanente-Anaheim, Anaheim, California, United States
PCR Oncology, Arroyo Grande, California, United States
Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States
Kaiser Permanente-Bellflower, Bellflower, California, United States
East Bay Radiation Oncology Center, Castro Valley, California, United States
Eden Hospital Medical Center, Castro Valley, California, United States
Valley Medical Oncology Consultants-Castro Valley, Castro Valley, California, United States
Feather River Cancer Center, Chico, California, United States
Bay Area Breast Surgeons Inc, Emeryville, California, United States
Epic Care Partners in Cancer Care, Emeryville, California, United States
Kaiser Permanente-Fontana, Fontana, California, United States
Valley Medical Oncology Consultants-Fremont, Fremont, California, United States
Kaiser Permanente - Harbor City, Harbor City, California, United States
Kaiser Permanente-Irvine, Irvine, California, United States
Long Beach Memorial Medical Center-Todd Cancer Institute, Long Beach, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
Kaiser Permanente-Cadillac, Los Angeles, California, United States
Contra Costa Regional Medical Center, Martinez, California, United States
Memorial Medical Center, Modesto, California, United States
El Camino Hospital, Mountain View, California, United States
Palo Alto Medical Foundation-Camino Division, Mountain View, California, United States
Highland General Hospital, Oakland, California, United States
Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States
Bay Area Tumor Institute, Oakland, California, United States
Hematology and Oncology Associates-Oakland, Oakland, California, United States
Tom K Lee Inc, Oakland, California, United States
Palo Alto Medical Foundation Health Care, Palo Alto, California, United States
Kaiser Permanente - Panorama City, Panorama City, California, United States
Valley Care Health System - Pleasanton, Pleasanton, California, United States
Valley Medical Oncology Consultants, Pleasanton, California, United States
Kaiser Permanente-Riverside, Riverside, California, United States
Saint Helena Hospital, Saint Helena, California, United States
Kaiser Permanente-San Diego Mission, San Diego, California, United States
Kaiser Permanente-San Diego Zion, San Diego, California, United States
Naval Medical Center -San Diego, San Diego, California, United States
Kaiser Permanente-San Marcos, San Marcos, California, United States
Doctors Medical Center- JC Robinson Regional Cancer Center, San Pablo, California, United States
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California, United States
Northbay Cancer Center, Vacaville, California, United States
Kaiser Permanente-Woodland Hills, Woodland Hills, California, United States
Poudre Valley Hospital, Fort Collins, Colorado, United States
Hartford Hospital, Hartford, Connecticut, United States
Middlesex Hospital, Middletown, Connecticut, United States
The Hospital of Central Connecticut, New Britain, Connecticut, United States
Beebe Medical Center, Lewes, Delaware, United States
Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States
Nanticoke Memorial Hospital, Seaford, Delaware, United States
MedStar Georgetown University Hospital, Washington, District of Columbia, United States
Sibley Memorial Hospital, Washington, District of Columbia, United States
Howard University Hospital, Washington, District of Columbia, United States
Boca Raton Comprehensive Cancer Center, Boca Raton, Florida, United States
Florida Hospital Memorial Medical Center, Daytona Beach, Florida, United States
Holy Cross Hospital, Fort Lauderdale, Florida, United States
Broward Health Medical Center, Fort Lauderdale, Florida, United States
Jupiter Medical Center, Jupiter, Florida, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
AdventHealth Orlando, Orlando, Florida, United States
John B Amos Cancer Center, Columbus, Georgia, United States
Memorial Health University Medical Center, Savannah, Georgia, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States
Saint Anthony's Health, Alton, Illinois, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Mount Sinai Hospital Medical Center, Chicago, Illinois, United States
Hematology and Oncology Associates, Chicago, Illinois, United States
Swedish Covenant Hospital, Chicago, Illinois, United States
Presence Resurrection Medical Center, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Weiss Memorial Hospital, Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States
Presence Saint Joseph Hospital-Chicago, Chicago, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
AMITA Health Alexian Brothers Medical Center, Elk Grove Village, Illinois, United States
Elmhurst Memorial Hospital, Elmhurst, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States
Saint Francis Hospital, Evanston, Illinois, United States
Presence Saint Mary's Hospital, Kankakee, Illinois, United States
AMITA Health Adventist Medical Center, La Grange, Illinois, United States
Garneau, Stewart C MD (UIA Investigator), Moline, Illinois, United States
Porubcin, Michael MD (UIA Investigator), Moline, Illinois, United States
Spector, David MD (UIA Investigator), Moline, Illinois, United States
Trinity Medical Center, Moline, Illinois, United States
Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States
AMG Oncology - Naperville, Naperville, Illinois, United States
Edward Hospital/Cancer Center, Naperville, Illinois, United States
West Suburban Medical Center, River Forest, Illinois, United States
Swedish American Hospital, Rockford, Illinois, United States
OSF Saint Anthony Medical Center, Rockford, Illinois, United States
Hematology Oncology Associates of Illinois - Skokie, Skokie, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
Elkhart Clinic, Elkhart, Indiana, United States
Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana, United States
Elkhart General Hospital, Elkhart, Indiana, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview, Fort Wayne, Indiana, United States
Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana, United States
Community Howard Regional Health, Kokomo, Indiana, United States
IU Health La Porte Hospital, La Porte, Indiana, United States
Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States
Cancer Care Partners LLC, Mishawaka, Indiana, United States
Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana, United States
Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana, United States
Michiana Hematology Oncology PC-Plymouth, Plymouth, Indiana, United States
Memorial Hospital of South Bend, South Bend, Indiana, United States
Michiana Hematology Oncology PC-South Bend, South Bend, Indiana, United States
South Bend Clinic, South Bend, Indiana, United States
Northern Indiana Cancer Research Consortium, South Bend, Indiana, United States
Michiana Hematology Oncology PC-Westville, Westville, Indiana, United States
McFarland Clinic PC - Ames, Ames, Iowa, United States
Constantinou, Costas L MD (UIA Investigator), Bettendorf, Iowa, United States
Mercy Hospital, Cedar Rapids, Iowa, United States
Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States
Mercy Capitol, Des Moines, Iowa, United States
Iowa Methodist Medical Center, Des Moines, Iowa, United States
Iowa-Wide Oncology Research Coalition NCORP, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
Iowa Lutheran Hospital, Des Moines, Iowa, United States
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa, United States
Iowa City VA Healthcare System, Iowa City, Iowa, United States
Mercy Medical Center - North Iowa, Mason City, Iowa, United States
Ottumwa Regional Health Center, Ottumwa, Iowa, United States
Siouxland Regional Cancer Center, Sioux City, Iowa, United States
Mercy Medical Center-Sioux City, Sioux City, Iowa, United States
Saint Luke's Regional Medical Center, Sioux City, Iowa, United States
Cedar Valley Medical Specialists, Waterloo, Iowa, United States
Hospital District Sixth of Harper County, Anthony, Kansas, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States
Cancer Center of Kansas-Independence, Independence, Kansas, United States
Providence Medical Center, Kansas City, Kansas, United States
Cancer Center of Kansas-Kingman, Kingman, Kansas, United States
Lawrence Memorial Hospital, Lawrence, Kansas, United States
Cancer Center of Kansas-Liberal, Liberal, Kansas, United States
Cancer Center of Kansas - McPherson, McPherson, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Menorah Medical Center, Overland Park, Kansas, United States
Saint Luke's South Hospital, Overland Park, Kansas, United States
Cancer Center of Kansas - Parsons, Parsons, Kansas, United States
Kansas City NCI Community Oncology Research Program, Prairie Village, Kansas, United States
Cancer Center of Kansas - Pratt, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Shawnee Mission Medical Center-KCCC, Shawnee Mission, Kansas, United States
Cotton O'Neil Cancer Center / Stormont Vail Health, Topeka, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Associates In Womens Health, Wichita, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
Via Christi Regional Medical Center, Wichita, Kansas, United States
Wichita NCI Community Oncology Research Program, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Doctors Carrol, Sheth, Raghavan, Louisville, Kentucky, United States
Baton Rouge General Medical Center, Baton Rouge, Louisiana, United States
Hematology/Oncology Clinic LLP, Baton Rouge, Louisiana, United States
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States
Ochsner Health Center-Summa, Baton Rouge, Louisiana, United States
Louisiana State University Health Science Center, New Orleans, Louisiana, United States
Tulane University Health Sciences Center, New Orleans, Louisiana, United States
University Medical Center New Orleans, New Orleans, Louisiana, United States
Ochsner Baptist Medical Center, New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Eastern Maine Medical Center, Bangor, Maine, United States
Saint Mary's Regional Medical Center, Lewiston, Maine, United States
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland, United States
Veterans Administration Medical Center-Baltimore, Baltimore, Maryland, United States
MedStar Harbor Hospital, Baltimore, Maryland, United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore, Maryland, United States
UM Upper Chesapeake Medical Center, Bel Air, Maryland, United States
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Union Hospital of Cecil County, Elkton, Maryland, United States
Sturdy Memorial Hospital, Attleboro, Massachusetts, United States
Beverly Hospital, Beverly, Massachusetts, United States
Addison Gilbert Hospital, Gloucester, Massachusetts, United States
Bixby Medical Center, Adrian, Michigan, United States
Hickman Cancer Center, Adrian, Michigan, United States
Green Bay Oncology - Escanaba, Escanaba, Michigan, United States
Green Bay Oncology - Iron Mountain, Iron Mountain, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
UP Health System Marquette, Marquette, Michigan, United States
Mercy Memorial Hospital, Monroe, Michigan, United States
Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States
Lakeland Hospital Niles, Niles, Michigan, United States
William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States
Lakeland Medical Center Saint Joseph, Saint Joseph, Michigan, United States
Marie Yeager Cancer Center, Saint Joseph, Michigan, United States
Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Essentia Health Cancer Center, Duluth, Minnesota, United States
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States
Miller-Dwan Hospital, Duluth, Minnesota, United States
Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States
Fairview-Southdale Hospital, Edina, Minnesota, United States
Unity Hospital, Fridley, Minnesota, United States
Hutchinson Area Health Care, Hutchinson, Minnesota, United States
Mayo Clinic Health Systems-Mankato, Mankato, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States
Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Minneapolis VA Medical Center, Minneapolis, Minnesota, United States
New Ulm Medical Center, New Ulm, Minnesota, United States
North Memorial Medical Health Center, Robbinsdale, Minnesota, United States
Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States
Regions Hospital, Saint Paul, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center, Shakopee, Minnesota, United States
Lakeview Hospital, Stillwater, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
Rice Memorial Hospital, Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States
Gulfport Memorial Hospital, Gulfport, Mississippi, United States
Forrest General Hospital / Cancer Center, Hattiesburg, Mississippi, United States
Singing River Hospital, Pascagoula, Mississippi, United States
Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States
Cox Cancer Center Branson, Branson, Missouri, United States
Southeast Missouri Hospital, Cape Girardeau, Missouri, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
Southeast Cancer Center, Cape Girardeau, Missouri, United States
Saint Luke's Hospital, Chesterfield, Missouri, United States
Veterans Administration, Columbia, Missouri, United States
University of Missouri - Ellis Fischel, Columbia, Missouri, United States
Centerpoint Medical Center LLC, Independence, Missouri, United States
Capital Region Southwest Campus, Jefferson City, Missouri, United States
Freeman Health System, Joplin, Missouri, United States
Mercy Hospital Joplin, Joplin, Missouri, United States
Truman Medical Center, Kansas City, Missouri, United States
Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States
Saint Joseph Health Center, Kansas City, Missouri, United States
North Kansas City Hospital, Kansas City, Missouri, United States
Heartland Hematology and Oncology Associates Incorporated, Kansas City, Missouri, United States
Research Medical Center, Kansas City, Missouri, United States
Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, United States
Liberty Radiation Oncology Center, Liberty, Missouri, United States
Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States
Heartland Regional Medical Center, Saint Joseph, Missouri, United States
Saint Joseph Oncology Inc, Saint Joseph, Missouri, United States
Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Center for Cancer Care and Research, Saint Louis, Missouri, United States
Comprehensive Cancer Care PC, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Saint Louis-Cape Girardeau CCOP, Saint Louis, Missouri, United States
Cancer Research for the Ozarks NCORP, Springfield, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
CoxHealth South Hospital, Springfield, Missouri, United States
Billings Clinic Cancer Center, Billings, Montana, United States
Northern Rockies Radiation Oncology Center, Billings, Montana, United States
Saint Vincent Healthcare, Billings, Montana, United States
Montana Cancer Consortium NCORP, Billings, Montana, United States
Saint Vincent Frontier Cancer Center, Billings, Montana, United States
Bozeman Deaconess Hospital, Bozeman, Montana, United States
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States
Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States
Berdeaux, Donald MD (UIA Investigator), Great Falls, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Northern Montana Hospital, Havre, Montana, United States
Saint Peter's Community Hospital, Helena, Montana, United States
Glacier Oncology PLLC, Kalispell, Montana, United States
Kalispell Medical Oncology, Kalispell, Montana, United States
Kalispell Regional Medical Center, Kalispell, Montana, United States
Montana Cancer Specialists, Missoula, Montana, United States
Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States
Guardian Oncology and Center for Wellness, Missoula, Montana, United States
Nebraska Cancer Research Center, Lincoln, Nebraska, United States
Great Plains Health Callahan Cancer Center, North Platte, Nebraska, United States
Missouri Valley Cancer Consortium, Omaha, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States
Alegent Health Lakeside Hospital, Omaha, Nebraska, United States
Creighton University Medical Center, Omaha, Nebraska, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
University Medical Center of Southern Nevada, Las Vegas, Nevada, United States
Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada, United States
New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire, United States
Exeter Hospital, Exeter, New Hampshire, United States
New Hampshire Oncology Hematology PA-Hooksett, Hooksett, New Hampshire, United States
LRGHealthcare-Lakes Region General Hospital, Laconia, New Hampshire, United States
Norris Cotton Cancer Center-Manchester, Manchester, New Hampshire, United States
Cooper Hospital University Medical Center, Camden, New Jersey, United States
Veterans Adminstration New Jersey Health Care System, East Orange, New Jersey, United States
Newark Beth Israel Medical Center, Newark, New Jersey, United States
Community Medical Center, Toms River, New Jersey, United States
Inspira Medical Center Vineland, Vineland, New Jersey, United States
Mary Imogene Bassett Hospital, Cooperstown, New York, United States
Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York, United States
Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York, United States
Glens Falls Hospital, Glens Falls, New York, United States
Orange Regional Medical Center, Middletown, New York, United States
NYP/Weill Cornell Medical Center, New York, New York, United States
Highland Hospital, Rochester, New York, United States
Interlakes Foundation Inc-Rochester, Rochester, New York, United States
University of Rochester, Rochester, New York, United States
State University of New York Upstate Medical University, Syracuse, New York, United States
Syracuse Veterans Administration Medical Center, Syracuse, New York, United States
Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States
Durham VA Medical Center, Durham, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Wayne Memorial Hospital, Goldsboro, North Carolina, United States
East Carolina University, Greenville, North Carolina, United States
Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina, United States
Vidant Oncology-Kinston, Kinston, North Carolina, United States
Southeastern Regional Medical Center, Lumberton, North Carolina, United States
Granville Medical Center, Oxford, North Carolina, United States
Duke Raleigh Hospital, Raleigh, North Carolina, United States
Nash General Hospital, Rocky Mount, North Carolina, United States
Person Memorial Hospital, Roxboro, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Mid Dakota Clinic, Bismarck, North Dakota, United States
Saint Alexius Medical Center, Bismarck, North Dakota, United States
Sanford Bismarck Medical Center, Bismarck, North Dakota, United States
Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States
Altru Cancer Center, Grand Forks, North Dakota, United States
Cleveland Clinic Akron General, Akron, Ohio, United States
Mary Rutan Hospital, Bellefontaine, Ohio, United States
Strecker Cancer Center-Belpre, Belpre, Ohio, United States
Toledo Clinic Cancer Centers-Bowling Green, Bowling Green, Ohio, United States
Mercy Medical Center, Canton, Ohio, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
North Coast Cancer Care-Clyde, Clyde, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Mount Carmel East Hospital, Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Columbus NCI Community Oncology Research Program, Columbus, Ohio, United States
Grant Medical Center, Columbus, Ohio, United States
The Mark H Zangmeister Center, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Doctors Hospital, Columbus, Ohio, United States
Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Hematology Oncology Center Incorporated, Elyria, Ohio, United States
Mercy Cancer Center-Elyria, Elyria, Ohio, United States
Fairfield Medical Center, Lancaster, Ohio, United States
Saint Rita's Medical Center, Lima, Ohio, United States
Lima Memorial Hospital, Lima, Ohio, United States
Marietta Memorial Hospital, Marietta, Ohio, United States
Saint Luke's Hospital, Maumee, Ohio, United States
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center, Maumee, Ohio, United States
Knox Community Hospital, Mount Vernon, Ohio, United States
Licking Memorial Hospital, Newark, Ohio, United States
Fisher-Titus Medical Center, Norwalk, Ohio, United States
Saint Charles Hospital, Oregon, Ohio, United States
Toledo Clinic Cancer Centers-Oregon, Oregon, Ohio, United States
Southern Ohio Medical Center, Portsmouth, Ohio, United States
North Coast Cancer Care, Sandusky, Ohio, United States
Springfield Regional Medical Center, Springfield, Ohio, United States
Trinity's Tony Teramana Cancer Center, Steubenville, Ohio, United States
ProMedica Flower Hospital, Sylvania, Ohio, United States
Mercy Hospital of Tiffin, Tiffin, Ohio, United States
The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio, United States
Saint Vincent Mercy Medical Center, Toledo, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Toledo Community Hospital Oncology Program CCOP, Toledo, Ohio, United States
Mercy Saint Anne Hospital, Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States
Fulton County Health Center, Wauseon, Ohio, United States
Saint Ann's Hospital, Westerville, Ohio, United States
Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States
Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States
Cancer Care Associates-Norman, Norman, Oklahoma, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States
Mercy Physicians of Oklahoma-Lakeside, Oklahoma City, Oklahoma, United States
Clackamas Radiation Oncology Center, Clackamas, Oregon, United States
Bay Area Hospital, Coos Bay, Oregon, United States
Providence Milwaukie Hospital, Milwaukie, Oregon, United States
Providence Newberg Medical Center, Newberg, Oregon, United States
Providence Willamette Falls Medical Center, Oregon City, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Saint Vincent Medical Center, Portland, Oregon, United States
Salem Hospital, Salem, Oregon, United States
Mid-Columbia Medical Center/Celilo Cancer Center, The Dalles, Oregon, United States
Butler Memorial Hospital, Butler, Pennsylvania, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
Easton Hospital, Easton, Pennsylvania, United States
Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States
Temple University Hospital, Philadelphia, Pennsylvania, United States
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States
Mercy Hospital, Scranton, Pennsylvania, United States
Scranton Hematology Oncology, Scranton, Pennsylvania, United States
Geisinger Medical Group, State College, Pennsylvania, United States
Chester County Hospital, West Chester, Pennsylvania, United States
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States
Memorial Hospital of Rhode Island, Pawtucket, Rhode Island, United States
Rhode Island Hospital, Providence, Rhode Island, United States
Miriam Hospital, Providence, Rhode Island, United States
Beaufort Memorial Hospital, Beaufort, South Carolina, United States
Roper Hospital, Charleston, South Carolina, United States
Greenville Health System Cancer Institute-Easley, Easley, South Carolina, United States
McLeod Regional Medical Center, Florence, South Carolina, United States
Greenville Health System Cancer Institute-Andrews, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Butternut, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States
Greenville Memorial Hospital, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States
Self Regional Healthcare, Greenwood, South Carolina, United States
Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States
Coastal Cancer Center-Myrtle Beach, Myrtle Beach, South Carolina, United States
Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States
Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States
Rapid City Regional Hospital, Rapid City, South Dakota, United States
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota, United States
Medical X-Ray Center, Sioux Falls, South Dakota, United States
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States
Nashville Oncology Associates PC, Nashville, Tennessee, United States
Meharry Medical College, Nashville, Tennessee, United States
Dallas VA Medical Center, Dallas, Texas, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas, United States
Baylor Saint Luke's Medical Center, Houston, Texas, United States
Ben Taub General Hospital, Houston, Texas, United States
Michael E DeBakey VA Medical Center, Houston, Texas, United States
The Methodist Hospital System, Houston, Texas, United States
Scott and White Memorial Hospital, Temple, Texas, United States
Southwestern Vermont Medical Center, Bennington, Vermont, United States
Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont, United States
University of Vermont and State Agricultural College, Burlington, Vermont, United States
University of Virginia Cancer Center, Charlottesville, Virginia, United States
Danville Regional Medical Center, Danville, Virginia, United States
Fredericksburg Oncology Inc, Fredericksburg, Virginia, United States
Centra Lynchburg Hematology-Oncology Clinic Inc, Lynchburg, Virginia, United States
Sovah Health Martinsville, Martinsville, Virginia, United States
Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia, United States
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States
VCU Community Memorial Health Center, South Hill, Virginia, United States
PeaceHealth Southwest Medical Center, Vancouver, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington, United States
Edwards Comprehensive Cancer Center, Huntington, West Virginia, United States
Saint Mary's Medical Center, Huntington, West Virginia, United States
West Virginia University Healthcare, Morgantown, West Virginia, United States
Camden Clark Medical Center, Parkersburg, West Virginia, United States
Wheeling Hospital/Schiffler Cancer Center, Wheeling, West Virginia, United States
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States
Marshfield Clinic-Chippewa Center, Chippewa Falls, Wisconsin, United States
Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States
Saint Agnes Hospital/Agnesian Cancer Center, Fond Du Lac, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States
Mercy Health System, Janesville, Wisconsin, United States
Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
Mayo Clinic Health System-Franciscan Healthcare, La Crosse, Wisconsin, United States
Dean Hematology and Oncology Clinic, Madison, Wisconsin, United States
Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States
Bay Area Medical Center, Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States
Marshfield Medical Center, Marshfield, Wisconsin, United States
Columbia Saint Mary's Hospital - Ozaukee, Mequon, Wisconsin, United States
Columbia Saint Mary's Water Tower Medical Commons, Milwaukee, Wisconsin, United States
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States
Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin, United States
Wheaton Franciscan Cancer Care - All Saints, Racine, Wisconsin, United States
Ascension Saint Mary's Hospital, Rhinelander, Wisconsin, United States
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin, United States
HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin, United States
Ascension Saint Michael's Hospital, Stevens Point, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin, United States
Marshfield Clinic - Weston Center, Weston, Wisconsin, United States
Aspirus UW Cancer Center, Wisconsin Rapids, Wisconsin, United States
Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States
Rocky Mountain Oncology, Casper, Wyoming, United States
Welch Cancer Center, Sheridan, Wyoming, United States
Contact Details
Name: Mark A Socinski
Affiliation: Alliance for Clinical Trials in Oncology
Role: PRINCIPAL_INVESTIGATOR
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