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Spots Global Cancer Trial Database for Efficacy of Propranolol Treatment to Prevent Melanoma Progression

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Trial Identification

Brief Title: Efficacy of Propranolol Treatment to Prevent Melanoma Progression

Official Title: Phase 2 Prospective Study of the Efficacy of Propranolol on Malignant Melanoma Progression. A Randomized Placebo-controlled,Single Blind Trial

Study ID: NCT01988831

Study Description

Brief Summary: Melanoma's incidence is increasing worldwide. The efforts made in melanoma screening led to an earlier detection of the primary tumour and a better prognosis, but melanoma remains an aggressive cancer when it comes to its metastatic stage. Three recent retrospective studies compared groups of patients diagnosed with primary melanoma and treated with betablockers for another indication to patients who never received betablockers. In these three studies, the outcome of the disease is significantly better for people under betablocker treatment with a decreased rate of recurrence and a better 5 years survival rate. Here we want to investigate the efficacy and the tolerability of an adjuvant treatment with propranolol for patients suffering from a primary melanoma with a high risk of recurrence.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Hôpital universitaire de Genève, Geneva, GE, Switzerland

Contact Details

Name: Frédérique-Anne Le Gal, MD/PhD

Affiliation: Hôpital cantonal universitaire de Genève

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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