Spots Global Cancer Trial Database for Second-Line Chemotherapy With Ramucirumab +/- Paclitaxel in Elderly Advanced Gastric or Gastroesophageal Junction Cancer Patients
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Trial Identification
Brief Title: Second-Line Chemotherapy With Ramucirumab +/- Paclitaxel in Elderly Advanced Gastric or Gastroesophageal Junction Cancer Patients
Official Title: Second-Line Chemotherapy With Ramucirumab +/- Paclitaxel in Elderly Advanced Gastric or Gastroesophageal Junction Cancer Patients
Study ID: NCT03760822
Study Description
Brief Summary: The primary objective is to evaluate six months survival rate and quality of life at 4 months of ramucirumab alone or in combination with paclitaxel in patients aged 70 years or more who have stomach or GEJ adenocarcinoma and whose first line of fluoropyrimidine- and platinumcontaining treatment has failed. The co-primary endpoints are the following: * Six months survival rate * Quality of life at 4 months as assessed by the following three target dimensions of the EORTC QLQ-ELD14 questionnaire: mobility, illness burden and worries about the future
Detailed Description:
Eligibility
Minimum Age: 70 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
CH -, Abbeville, , France
CH - Albi, Albi, , France
PRIVEE - L'Europe, Amiens, , France
CAC - ICO Site Paul Papin, Angers, , France
Privee - Hopital Prive, Antony, , France
Ch - Victor Dupouy, Argenteuil, , France
Ch - Metz Thionville Mercy, Ars-Laquenexy, , France
Ch - Ght Unyon Auxerre, Auxerre, , France
Privee - Institut Du Cancer Avignon Provence, Avignon, , France
Ch - Cote Basque, Bayonne, , France
Ch - Beauvais Ch, Beauvais, , France
Chu - Jean Minjoz, Besançon, , France
Privee - Tivoli, Bordeaux, , France
PRIVEE - Polyclinique Saint Privat, Boujan-sur-Libron, , France
Ch - Duchenne, Boulogne-sur-Mer, , France
Ch - Pierre Oudot, Bourgoin-Jallieu, , France
Privee - Pasteur Lanroze, Brest, , France
Cac - François Baclesse, Caen, , France
Chu - Côte de Nacre, Caen, , France
Ch - Jean Rougier, Cahors, , France
Privee - Infirmerie Protestante, Caluire-et-Cuire, , France
CH -, Carcassonne, , France
Ch - Castres Mazamet Chi, Castres, , France
Prive - Médipole de Savoie, Challes-les-Eaux, , France
Prive - Sainte Marie, Chalon-sur-Saône, , France
CH -, Cholet, , France
Ch - Hopitaux Civils de Colmar, Colmar, , France
Hopitaux civils de Colmar, Colmar, , France
Chu - Louis Mourier, Colombes, , France
Prive - Saint Côme, Compiègne, , France
Prive - Cédres, Cornebarrieu, , France
Chu - Henri Mondor, Créteil, , France
Prive - Centre Leonard de Vinci, Dechy, , France
Cac - Gf Leclerc, Dijon, , France
Chu - Francois Mitterrand, Dijon, , France
CH -, Dunkerque, , France
CHI - Elbeuf Louviers Val de Reuil, Elbeuf, , France
Clinique privée - CENTRE CARIO, Plérin, , France
Contact Details
Name: Astrid Lièvre, Pr
Affiliation: CHU de Pontchaillou - Rennes
Role: PRINCIPAL_INVESTIGATOR
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