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Brief Title: Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
Official Title: Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embolic Stroke of Undetermined Source (RESPECT ESUS)
Study ID: NCT02239120
Brief Summary: This trial will enroll approximately 6,000 patients with recent embolic stroke of unknown source (ESUS). Patients will be randomized to dabigatran or acetylsalicyclic acid (ASA) (1:1 ratio) and have visits every three months. The study doctor may prescribe blinded concomitant ASA for pts with coronary artery disease but this is not mandatory. All Adverse Events (AEs), Serious Adverse Events (SAEs), outcome events will be recorded. The trial will conclude when the required number of stroke events are positively adjudicated which is estimated to take 3 years (including 2.5 years of enrollment).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Bronislava Shafran, MD PC, Phoenix, Arizona, United States
Westside Medical Associates of Los Angeles, Beverly Hills, California, United States
TriWest Research Associates, LLC, El Cajon, California, United States
University of California, Fresno, California, United States
Glendale Adventist Medical Center, Glendale, California, United States
Collaborative Neuroscience Network, LLC (CNS), Long Beach, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
University of California Los Angeles, Los Angeles, California, United States
Huntington Hospital, Pasadena, California, United States
University of California, San Diego, California, United States
University of California, San Francisco, California, United States
University of Colorado Denver, Aurora, Colorado, United States
Colorado Neurological Institute, Englewood, Colorado, United States
University of Colorado Denver, Fort Collins, Colorado, United States
St. Mary's Hospital and Regional Medical Center, Grand Junction, Colorado, United States
Hartford Hospital, Hartford, Connecticut, United States
JEM Research Institute, Atlantis, Florida, United States
Boca Raton Regional Hospital, Boca Raton, Florida, United States
Tenet Florida Physician Services, Boynton Beach, Florida, United States
Nova Clinical Research, LLC, Bradenton, Florida, United States
Broward Health North, Deerfield Beach, Florida, United States
Center for Advanced Research Excellence, Hialeah, Florida, United States
Bruce W. Carter, Miami VA Healthcare System, Miami, Florida, United States
University of Miami, Miami, Florida, United States
Bay Neurological Institute, Panama City, Florida, United States
Carol L Pappas, MD PhD PA, Saint Petersburg, Florida, United States
University of South Florida, Tampa, Florida, United States
Vero Beach Neurology and Research Institute, Vero Beach, Florida, United States
Palm Beach Neuroscience Institute, West Palm Beach, Florida, United States
Augusta University, Augusta, Georgia, United States
WellStar Medical Group - Neurosurgery, Marietta, Georgia, United States
The Queen's Medical Center, Honolulu, Hawaii, United States
Saint Alphonsus Medical Center-Neurology, Boise, Idaho, United States
Northwest Heart Clinical Research, LLC, Arlington Heights, Illinois, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
University of Chicago, Chicago, Illinois, United States
Medicoricium, LLC, Fairview Heights, Illinois, United States
OSF Saint Francis Medical Center, Peoria, Illinois, United States
Quincy Physicians and Surgeons Clinic, S.C., Quincy, Illinois, United States
Southern Illinois University School of Medicine, Springfield, Illinois, United States
Community Clinical Research Center, Anderson, Indiana, United States
Ruan Neurology Clinic and Research Center, Des Moines, Iowa, United States
Associates in Neurology, PSC, Lexington, Kentucky, United States
University of Louisville, Louisville, Kentucky, United States
Alexandria Cardiology Clinic, Alexandria, Louisiana, United States
Culicchia Neurological Clinic, Marrero, Louisiana, United States
Tulane University Hospital and Clinic, New Orleans, Louisiana, United States
Ochsner Medical Center, New Orleans, Louisiana, United States
Anne Arundel Medical Center, Annapolis, Maryland, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Newton-Wellesley Hospital, Newton, Massachusetts, United States
Henry Ford Health System, Detroit, Michigan, United States
McLaren Flint, Flint, Michigan, United States
Mercy Health Saint Mary's, Grand Rapids, Michigan, United States
Spectrum Health Medical Center, Grand Rapids, Michigan, United States
Sparrow Clinical Research Institute, Lansing, Michigan, United States
St. Joseph Mercy Oakland, Pontiac, Michigan, United States
The Duluth Clinic dba Essentia Health Duluth Clinic, Duluth, Minnesota, United States
Abbott Northwestern Hospital, Radiology Department, Minneapolis, Minnesota, United States
HealthPartners Neuroscience Center, Saint Paul, Minnesota, United States
Jackson Heart Clinic, P.A., Jackson, Mississippi, United States
Boone Hospital Center, Columbia, Missouri, United States
University of Missouri Health System, Columbia, Missouri, United States
SSM Health St. Clare Hospital, Fenton, Missouri, United States
Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States
Saint Louis University, Saint Louis, Missouri, United States
St. Louis Heart and Vascular, P.C., Saint Louis, Missouri, United States
The Nebraska Medical Center, Omaha, Nebraska, United States
Renown Institute for Neurosciences, Reno, Nevada, United States
NYC Health + Hospitals/Coney Island, Brooklyn, New York, United States
New York Presbyterian Hudson Valley Hospital, Cortlandt Manor, New York, United States
UHS Wilson Medical Center,Office of Clin Trials, Johnson City, New York, United States
North Shore University Hospital, Manhasset, New York, United States
Winthrop University Hospital, Mineola, New York, United States
Mount Sinai Beth Israel, New York, New York, United States
Novant Health Neurology Specialists, Charlotte, North Carolina, United States
Duke Clinic 1L, Durham, North Carolina, United States
Cone Health System, Greensboro, North Carolina, United States
Novant Health Neurology Hickory, Hickory, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Altru Health System, Grand Forks, North Dakota, United States
The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
Holzer Clinic LLC, Gallipolis, Ohio, United States
Advanced Neurology Associates, Youngstown, Ohio, United States
Oregon Health and Sciences University, Portland, Oregon, United States
Veterans Affairs Portland Health Care System, Portland, Oregon, United States
Sacred Heart Medical Center at RiverBend, Springfield, Oregon, United States
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Temple University Hospital, Philadelphia, Pennsylvania, United States
Abington Neurological Associates, Willow Grove, Pennsylvania, United States
Rhode Island Hospital, Providence, Rhode Island, United States
Greenville Memorial Hospital, Greenville, South Carolina, United States
Methodist University Hospital, Memphis, Tennessee, United States
Centennial Heart Cardiovascular Consultants, LLC, Nashville, Tennessee, United States
Saint Thomas Health, Nashville, Tennessee, United States
Seton Medical Center Austin, Austin, Texas, United States
Houston Methodist Hospital, Houston, Texas, United States
Bhupesh Dihenia, M.D.,P.A., Lubbock, Texas, United States
University of Vermont, Burlington, Vermont, United States
Virginia Commonwealth University, Richmond, Virginia, United States
Carilion Riverside, Roanoke, Virginia, United States
Virginia Mason Medical Center, Seattle, Washington, United States
Swedish Neuroscience Institute, Seattle, Washington, United States
Marshall University, Huntington, West Virginia, United States
Aurora BayCare Medical Center, Green Bay, Wisconsin, United States
University of Wisconsin, Madison, Wisconsin, United States
STAT Research, Caba, , Argentina
Fundación Favaloro, Caba, , Argentina
Hospital Italiano de Buenos Aires, Caba, , Argentina
Instituto Médico DAMIC S.R.L., Cordoba, , Argentina
Clinica Coronel Suarez SA, Coronel Suarez, , Argentina
Hospital Privado de Comunidad, Mar del Plata, , Argentina
Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
St Vincent's Hospital Sydney, Darlinghurst, New South Wales, Australia
Kanwal Medical Complex, Kanwal, New South Wales, Australia
John Hunter Hospital, New Lambton, New South Wales, Australia
Royal North Shore Hospital, St Leonards, New South Wales, Australia
Sunshine Coast University Hospital, Birtinya, Queensland, Australia
Royal Brisbane and Women's Hospital, Herston, Queensland, Australia
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Calvary North Adelaide Hospital, Adelaide, South Australia, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Royal Melbourne Hospital, Parkville, Victoria, Australia
Alfred Health, Victoria, , Australia
LKH-Univ. Hospital Graz, Graz, , Austria
Medical University of Innsbruck, Innsbruck, , Austria
Kepler Univ. Klinikum Linz, Linz, , Austria
Kepler Univ. Klinikum Linz, Linz, , Austria
KH d. Barmherzigen Brüder Linz, Neurologie, Linz, , Austria
Universitätsklinikum Tulln, Abteilung für Neurologie, Tulln, , Austria
Hosp.Hietzing with Neuro.Centr Rosenhuegel,II Neuro.dep,Wien, Vienna, , Austria
Wilhelminenspital, Wien, , Austria
Aalst - HOSP Onze-Lieve-Vrouw, Aalst, , Belgium
Arlon - HOSP Sud Luxembourg - Vivalia, Arlon, , Belgium
AZ Sint-Jan Brugge, Brugge, , Belgium
Brussels-UNIV Brugmann -Horta, Brussel, , Belgium
Brussels - HOSP Europe (Ste-Elisabeth), Brussel, , Belgium
Brussels - UNIV Saint-Luc, Bruxelles, , Belgium
UNIV UZ Gent, Gent, , Belgium
Kortrijk - HOSP AZ Groeninge Kennedylaan, Kortrijk, , Belgium
UZ Leuven, Leuven, , Belgium
Liège - HOSP St-Joseph, Liège, , Belgium
Roeselare - HOSP AZ Delta, Roeselare, , Belgium
Rumst - HOSP AZ Heilige Familie, Rumst, , Belgium
Sint-Truiden - HOSP St-Trudo (St-Jozef), Sint-Truiden, , Belgium
Wilrijk - HOSP GZA (St-Augustinus), Wilrijk, , Belgium
Yvoir - UNIV UCL de Mont-Godinne, Yvoir, , Belgium
Hospital Clinicas de Botucatu, Botucatu, , Brazil
Instituto de Medicina Flumignano, Curitiba, , Brazil
Clinica Neurologica e Neurocirurgica de Joinvile, Joinvile, , Brazil
Hospital de Clínicas de Porto Alegre, Porto Alegre, , Brazil
H.C.da Fac. de Medicina de Ribeirao Preto, Ribeirao Preto, , Brazil
Hospital Quinta D¿Or, Rio de Janeiro, , Brazil
Foothills Medical Centre, Calgary, Alberta, Canada
University of Alberta Hospital (University of Alberta), Edmonton, Alberta, Canada
Grey Nuns Hospital, Edmonton, Alberta, Canada
Prairie Mountain Health, Brandon, Manitoba, Canada
Hopital Notre-Dame du CHUM, Montreal, Migration Data, Canada
Jewish General Hospital, Montreal, Migration Data, Canada
Saint John Regional Hospital, Saint John, New Brunswick, Canada
Eastern Health (MUN), St. John's, Newfoundland and Labrador, Canada
Victoria Hospital (LHSC), London, Ontario, Canada
St. Michael's Hospital, Toronto, Ontario, Canada
Toronto Western Hospital, Toronto, Ontario, Canada
CSSS de Chicoutimi, Chicoutimi, Quebec, Canada
Hopital Charles - LeMoyne, Greenfield Park, Quebec, Canada
Montreal General Hospital - McGill University Health Centre, Montreal, Quebec, Canada
CHUS Fleurimont, Sherbrooke, Quebec, Canada
St Jerome Medical Research Inc., St-Jerome, Quebec, Canada
CHU de Quebec-Universite Laval Research Centre, Quebec, , Canada
Clínica Alemana de Santiago S.A., Santiago, , Chile
Clínica Dávila, Santiago, , Chile
Clinica Alemana de Temuco, Temuco, , Chile
Beijing Tiantan Hospital affiliated to Cap Med University, Beijing, , China
Peking University Third Hospital, Beijing, , China
First Hospital of Jilin University, Changchun, , China
First Affiliated Hospital of Guangzhou Medical University, Guangzhou, , China
First Affiliated Hospital of Guangzhou University of TCM, Guangzhou, , China
The First Affiliated Hospital of Jinan University, Guangzhou, , China
The Affiliated Hospital of Guizhou Medical University, Guiyang, , China
2nd Affiliated Hosp Zhejiang University College of Medical, Hangzhou, , China
Zhejiang Hospital, Hangzhou, , China
The Affiliated Hospital of Hangzhou Normal University, Hangzhou, , China
Zhejiang University School of Medicine SIR RUN RUN SHAW Hospital, Hangzhou, , China
Jinlin Central Hospital, Jilin, , China
The Second Affiliated Hospital to Nanchang University, Nanchang, , China
Nanjing Drum Tower Hospital, Nanjing, , China
Zhongda Hospital Southeast University, Nanjing, , China
QingDao Municipal Hospital, Qingdao, , China
The affiliated hospital of medicalcollege qingdao university, Qingdao, , China
Huashan Hospital, Fudan University, Shanghai, , China
Tongji Hospital, Tongji University, Shanghai, , China
General Hospital of Shenyang Military Region, Shenyang, , China
First Affiliated Hospital of Xiamen University, Xiamen, , China
Affiliated Hospital, Xuzhou Medical college, Xuzhou, , China
Servicios Médicos Muñoz Solano, Bogotá, , Colombia
Sociedad de Cirugia de Bogota Hospital de San José, Bogotá, , Colombia
Fundación Valle del Lili, Cali, , Colombia
Fundación Cardiovascular de Colombia, Floridablanca, , Colombia
General Hospital Varazdin, Varazdin, , Croatia
Clin.Hosp.Centre Zagreb,Cerebrovascul.disease w/ intens.care, Zagreb, , Croatia
University hospital center Zagreb, Zagreb, , Croatia
Univ. Hosp. Sisters of Mercy, Neurology Clinic, Zagreb, Zagreb, , Croatia
Cerebrovascular site, private prac., Brno, Brno, , Czechia
Hospital Jihlava, Jihlava, , Czechia
University Hospital Olomouc, Olomouc, , Czechia
Cerebrovascular site, Ostrava, Ostrava, , Czechia
Cerebrovascular site, Ostrava, Ostrava, , Czechia
Hospital Homolka, Prague, Prague 5, , Czechia
University Hospital Motol, Praha 5, , Czechia
East Estonia Central Hospital, Neurology Dept, Ahtme, Ahtme, , Estonia
West Tallinn Central Hospital, Neurology Dept., Tallinn, , Estonia
North Estonia Medical Centre Foundation, Tallin, Tallinn, , Estonia
Tartu University Hospital, Tartu, , Estonia
HOP Pays d'Aix, Aix en Provence, , France
HOP de Bayonne, Bayonne, , France
HOP Jean Minjoz, Besançon, , France
HOP Pellegrin, Bordeaux, , France
HOP de la Cavale Blanche, Brest, , France
HOP Pierre Wertheimer, Bron, , France
HOP Côte de Nacre, Caen, , France
HOP Grenoble, Neuro, Grenoble, Grenoble, , France
HOP Roger Salengro, Lille, , France
HOP Mercy, Metz, , France
HOP Paris Saint-Joseph, Paris, , France
GHU Paris Psychiatrie et Neurosciences, Paris, , France
HOP Purpan, Toulouse, , France
Klinikum Altenburger Land GmbH, Altenburg, , Germany
Neurologische Klinik GmbH, Bad Neustadt, Bad Neustadt, , Germany
Vivantes Netzwerk für Gesundheit GmbH, Berlin, , Germany
Evangelisches Klinikum Bethel gGmbH, Bielefeld, , Germany
Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH, Bochum, , Germany
St. Josef- und St. Elisabeth-Hospital gGmbH, Bochum, , Germany
Gesundheit Nord gGmbH | Klinikverbund Bremen, Bremen, , Germany
Klinikum Bremerhaven, Bremen, , Germany
Krankenhäuser Buchholz und Winsen gGmbH, Buchholz, , Germany
Allgemeines Krankenhaus, Celle, Celle, , Germany
Klinikum Chemnitz gGmbH, Chemnitz, , Germany
Klinikum Coburg gGmbH, Coburg, , Germany
Klinikzentrum Mitte, Dortmund, Dortmund, , Germany
Städtisches Klinikum Dresden, Dresden, , Germany
Universitätsklinikum Carl Gustav Carus Dresden, Dresden, , Germany
Universitätsklinikum Düsseldorf, Düsseldorf, , Germany
Marien-Hospital, Düsseldorf, Düsseldorf, , Germany
Universitätsklinikum Erlangen, Erlangen, , Germany
Alfried Krupp Krankenhaus Essen, Essen, , Germany
Universitätsklinikum Essen AöR, Essen, , Germany
Universitätsklinikum Frankfurt, Frankfurt am Main, , Germany
Klinikum Frankfurt Höchst GmbH, Frankfurt, , Germany
Klinikum Friedrichshafen, Friedrichshafen, , Germany
Klinikum Fulda gAG, Fulda, , Germany
Evangelische Klinik Gelsenkirchen, Gelsenkirchen, , Germany
SRH Wald-Klinikum Gera GmbH, Gera, , Germany
Universitätsklinikum Gießen und Marburg GmbH, Gießen, , Germany
Universitätsmedizin Greifswald, Greifswald, , Germany
Bezirkskrankenhaus, Günzburg, Günzburg, , Germany
Asklepios Klinik St. Georg, Hamburg, , Germany
Universitätsklinikum Hamburg-Eppendorf, Hamburg, , Germany
Asklepios Klinik Harburg, Hamburg, , Germany
Asklepios Klinik Wandsbek, Hamburg, , Germany
Asklepios Klinik Barmbek, Hamburg, , Germany
Asklepios Klinik Altona, Hamburg, , Germany
Klinikum Hanau GmbH, Hanau, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Universitätsklinikum Heidelberg, Heidelberg, , Germany
SLK-Kliniken Heilbronn GmbH, Heilbronn, , Germany
Klinikum Idar-Oberstein, Idar-Oberstein, , Germany
Universitätsklinikum Jena, Jena, , Germany
Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, , Germany
Universitätsklinikum Köln (AöR), Köln, , Germany
Universitätsklinikum Leipzig, Leipzig, , Germany
Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen, , Germany
Universitätsklinikum Magdeburg AöR, Magdeburg, , Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, , Germany
Universitätsklinikum Gießen und Marburg GmbH, Marburg, , Germany
Elblandklinikum Meißen, Meißen, , Germany
Johannes Wesling Klinikum, Minden, , Germany
Kliniken Maria Hilf GmbH, Moenchengladbach, , Germany
Ökumenisches Hainich Klinikum gGmbH, Mühlhausen, , Germany
Klinikum der Universität München - Campus Großhadern, München, , Germany
Klinikum rechts der Isar der Technischen Universität München, München, , Germany
Universitätsklinikum Münster, Münster, , Germany
Klinikum Nürnberg, Nürnberg, , Germany
Sana Klinikum Offenbach GmbH, Offenbach, , Germany
Klinikum Osnabrück GmbH, Osnabrück, , Germany
Universitätsklinikum Regensburg, Regensburg, , Germany
Nordwest-Krankenhaus Sanderbusch gGmbH, Sande, , Germany
Kreisklinikum Siegen GmbH, Siegen, , Germany
Bürgerhospital, Stuttgart, Stuttgart, , Germany
Nervenklinik Teupitz, Teupitz, Teupitz, , Germany
Krankenhaus der Barmherzigen Brüder Trier, Trier, , Germany
Universitätsklinikum Tübingen, Tübingen, , Germany
RKU - Universitäts- und Rehabilitationskliniken Ulm gGmbH, Ulm, , Germany
Sophien- und Hufeland-Klinikum gGmbH, Weimar, , Germany
Helios Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, , Germany
Universitätsklinikum Würzburg, Würzburg, , Germany
Univ.Hosp. of Alexandroupolis, Alexandroupolis, , Greece
Gen.Hosp.of Ath.Evangelismos, Athens, , Greece
Attikon University Hospital, Athens, , Greece
Gen.Univ. Hosp. of Herakleion, Herakleion, , Greece
General University Hospital of Larissa, Larissa, , Greece
Univ. Gen. Hosp. of Patras, Patras, , Greece
Univ.Gen.Hosp. of Thessaloniki, Thessaloniki, , Greece
Prince of Wales Hospital, Hong Kong, , Hong Kong
Pamela Youde Nethersole Eastern Hospital, Hong Kong, , Hong Kong
Queen Mary Hospital, Hong Kong, , Hong Kong
Semmelweis University, Budapest, , Hungary
National Instit.of Neurosciences,Neurology Dept,Budapest, Budapest, , Hungary
Univ. Debrecen Medical Health Science Center, Neurology Dept, Debrecen, , Hungary
Pest Megyei Flor Ferenc Hospital, Kistarcsa, , Hungary
CRU Hungary Ltd, Private Practice, Miskolc, Miskolc, , Hungary
Univ. of Pecs Clinic for Neurology, Pecs, , Hungary
St. Johns medical College and Hospital, Bangalore, , India
Post Graduate Institute of Medical Education and Research, Chandigarh, , India
Lalitha Super Specialities Hospital, Guntur, , India
Nizam's Institute of Medical Sciences, Hyderabad, , India
Shree Krishna Hospital and Research Centre, Karamsad, , India
Caritas Hospital, Kottayam, , India
Mangala Hospital and Mangala Kidney Foundation, Mangalore, , India
LTMMC & GH Medical College,, Mumbai, , India
Magnum Heart Institute, Nashik, , India
All India Institute of Medical Sciences, New Delhi, , India
Sahyadri Speciality Hospital, Pune, , India
Hillel Yaffe Medical Center, Hadera, Hadera, , Israel
Wolfson Medical Center, Holon, , Israel
The Chaim Sheba Medical Center Tel Hashomer, Tel Hashomer, Ramat Gan, , Israel
Sourasky Medical Center, Telaviv, , Israel
Osp. SS Filippo Nicola, Avezzano, , Italy
Policlinico S. Orsola Malpighi, Bologna, , Italy
A.O. Spedali Civili di Brescia, Brescia, , Italy
Azienda Ospedaliero Universitaria di Ferrara, Cona (FE), , Italy
Policlinico San Martino, Genova, , Italy
A.O.U.Policlinico G.Martino, Messina, , Italy
Fondazione Centro San Raffaele del Monte Tabor, Milano, , Italy
Istituto Auxologico Italiano, Milano, , Italy
Nuovo Ospedale Civile S. Agostino-Estense, Modena, , Italy
Azienda Ospedaliera Universitaria di Padova, Padova, , Italy
Ospedale S.Maria della Misericordia, AO di Perugia, Perugia, , Italy
Osp. Guglielmo da Saliceto AUSL di Piacenza, Piacenza, , Italy
Ospedale Santa Corona Azienda Sanitaria Locale n.2 Savonese, Pietra Ligure, , Italy
Università degli Studi Campus Bio-Medico, Roma, , Italy
A.O. San Camillo Forlanini, Roma, , Italy
Umberto I Pol. di Roma-Università di Roma La Sapienza, Roma, , Italy
Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza, Roma, , Italy
A.O.U. Senese Policlinico Santa Maria alle Scotte, Siena, , Italy
Ospedale Molinette, AO Città della Salute e della, Torino, , Italy
Ospedale Maria Vittoria, Torino, , Italy
Ospedale S. Maria di Ca' Foncello Azienda ULSS9 TREVISO, Treviso, , Italy
A. O. Ospedale Circolo Fond. Macchi, Varese, , Italy
Ospedale Policlinico G.B. Rossi (Borgo Roma) di Verona, Verona, , Italy
Chubu Rosai Hospital, Aichi, Nagoya, , Japan
National Hospital Organization Toyohashi Medical Center, Aichi, Toyohashi, , Japan
Toyota Memorial Hospital, Aichi, Toyota, , Japan
Reserch Institute for Brain and Blood Vessels Akita, Akita, Akita, , Japan
Juntendo University Urayasu Hospital, Chiba, Urayasu, , Japan
Go Neurosurgical Clinic, Fukuoka, Chikushi-gun, , Japan
Fukuoka University Chikushi Hospital, Fukuoka, Chikushino, , Japan
National Hospital Organization Kyushu Medical Center, Fukuoka, Fukuoka, , Japan
Fukuoka Wajiro Hospital, Fukuoka, Fukuoka, , Japan
Fukuoka University Hospital, Fukuoka, Fukuoka, , Japan
Fukuoka Tokushukai Medical Center, Fukuoka, Kasuga, , Japan
Steel Memorial Yawata Hospital, Fukuoka, Kitakyushu, , Japan
Japan Community Health Care Organization Kyushu Hospital, Fukuoka, Kitakyushu, , Japan
St. Mary's Hospital, Fukuoka, Kurume, , Japan
Shin Koga Hospital, Fukuoka, Kurume, , Japan
Fukuoka Shin Mizumaki Hospital, Fukuoka, Onga, , Japan
Social Insurance Tagawa Hospital, Fukuoka, Tagawa, , Japan
Shin Yukuhashi Hospital, Fukuoka, Yukuhashi, , Japan
Fujita General Hospital, Fukushima, Date-Gun, , Japan
Shinseikai Masu Memorial Hospital, Fukushima, Nihonmatsu, , Japan
Asahi University Hospital, Gifu, Gifu, , Japan
Japanese Red Cross Takayama Hospital, Gifu, Takayama, , Japan
Mihara Memorial Hospital, Gunma, Isesaki, , Japan
Maebashi Red Cross Hospital, Gunma, Maebashi, , Japan
Medical corporation Suiseikai Suiseikai Kajikawa Hospital, Hiroshima, Hiroshima, , Japan
Araki Neurosurgical Hospital, Hiroshima, Hiroshima, , Japan
Hiroshima Prefectural Hospital, Hiroshima, Hiroshima, , Japan
Sapporo Shiroishi Memorial Hospital, Hokkaido, Sapporo, , Japan
Nakamura Memorial Hospital, Hokkaido, Sapporo, , Japan
Kobe City Medical Center General Hospital, Hyogo, Kobe, , Japan
JA Toride Medical Center, Ibaraki, Toride, , Japan
Tsukuba Medical Center Hospital, Ibaraki, Tsukuba, , Japan
Iwate Medical University Hospital, Iwate, Morioka, , Japan
Kagoshima City Hospital, Kagoshima, Kagoshima, , Japan
National Hospital Organization Kagoshima Medical Center, Kagoshima, Kagoshima, , Japan
Shonan Kamakura General Hospital, Kanagawa, Kamakura, , Japan
Saiseikai Kumamoto Hospital, Kumamoto, Kumamoto, , Japan
Japanese Red Cross Kumamoto Hospital, Kumamoto, Kumamoto, , Japan
Kumamoto City Hospital, Kumamoto, Kumamoto, , Japan
Uji-Tokushukai Medical Center, Kyoto, Uji, , Japan
National Hospital Organization Sendai Medical Center, Miyagi, Sendai, , Japan
South Miyagi Medical Center, Miyagi, Shibata-gun, , Japan
Ina Central Hospital, Nagano, Ina, , Japan
Nagano Municipal Hospital, Nagano, Naganoi, , Japan
Nagasaki University Hospital, Nagasaki, Nagasaki, , Japan
Nozaki Tokushukai Hospital, Osaka, Daito, , Japan
Higashiosaka City Medical Center, Osaka, Higashiosaka, , Japan
Wakakusa Daiichi Hospital, Osaka, Higashiosaka, , Japan
Rinku General Medical Center, Osaka, Izumisano, , Japan
Kishiwada Tokushukai Hospital, Osaka, Kishiwada, , Japan
Yagi Neurosurgical Hospital, Osaka, Osaka, , Japan
Tominaga Hospital, Osaka, Osaka, , Japan
Osaka University Hospital, Osaka, Suita, , Japan
TMG Asaka Medical Center, Saitama, Asaka, , Japan
Saitama Medical University International Medical Center, Saitama, Hidaka, , Japan
Sainokuni Higashiomiya Medical Center, Saitama, Saitama, , Japan
Saitama Municipal Hospital, Saitama, Saitama, , Japan
Nippon Medical School Hospital, Tokyo, Bunkyo-ku, , Japan
Tokyo Metropolitan Geriatric Hospital, Tokyo, Itabashi-ku, , Japan
Kyorin University Hospital, Tokyo, Mitaka, , Japan
Tokyo Women's Medical University Hospital, Tokyo, Shinjuku-ku, , Japan
Saiseikai Wakayama Hospital, Wakayama, Wakayama, , Japan
Yamagata City Hospital SAISEIKAN, Yamagata, Yamagata, , Japan
Hallym University Sacred Heart Hospital, Anyang, , Korea, Republic of
Dong-A University Hospital, Busan, , Korea, Republic of
Kyungpook National Univ. Hosp, Daegu, , Korea, Republic of
Chungnam National University Hospital, Daejoen, , Korea, Republic of
Inje University Ilsan Paik Hospital, Goyang, , Korea, Republic of
Chonnam National University Hospital, Gwangju, , Korea, Republic of
Chosun University Hospital, Gwangju, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam, , Korea, Republic of
Severance Hospital, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea, Seoul St.Mary's Hospital, Seoul, , Korea, Republic of
Chung-Ang University Hospital, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Kangdong Sacred Heart Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
SMG-SNU Boramae Medical Center, Seoul, , Korea, Republic of
Ajou University Hospital, Suwon, , Korea, Republic of
Sarawak General Hospital, Kuching, , Malaysia
Hospital Seberang Jaya, Pulau Pinang, , Malaysia
Hospital Sultanah Nur Zahirah, Terengganu, , Malaysia
Hospital General de Culiacán "Dr. Bernardo J. Gastellum", Culiacán, , Mexico
Hospital General "Dr. Miguel Silva", Morelia, , Mexico
Hospital Angeles del Pedregal, México, D.F., , Mexico
Hospital Universitario Dr Jose Eleuterio Gonzalez, Nuevo Leon, , Mexico
H. Central Dr Ignacio M. P., San Luis Potosi, , Mexico
Auckland City Hospital, Grafton / Auckland, , New Zealand
North Shore Hospital, Takapuna, Takpuna Auckland, , New Zealand
Wellington Hospital, Wellington, , New Zealand
Instituto Nacional de Ciencias Neurológicas, Barrios Altos, , Peru
Hospital Nacional Guillermo Almenara Irigoyen, La Victoria, , Peru
PI HOUSE Sp. z o.o., Gdansk, Gdansk, , Poland
Spec.Hosp.of Dr. Wladyslaw Bieganski in Grudziadz, Grudziadz, , Poland
Univ.Clin.Centr Gibinski of Silesian Med,Neurol.dep,Katowice, Katowice, , Poland
University Hospital in Krakow, Krakow, , Poland
Center of Clinical Neurology, private prac, Krakow, Krakow, , Poland
Clin.Research Center,Leszek Szczepanski,Private Prac.,Lublin, Lublin, , Poland
Medicome Sp. z o.o., Oswiecim, , Poland
Specialist Holy Spirit Hospital, Neurology Dept,Sandomierz, Sandomierz, , Poland
Public Central Clinical Hosp,Neurology Clinic,Warsaw, Warsaw, , Poland
Military Institute of Medicine Neurology Clinic, Warsaw, Warsaw, , Poland
Hospital Garcia de Orta, EPE, Almada, , Portugal
Hospital Fernando Fonseca, EPE, Amadora, , Portugal
Hospital de Braga - Centro Clínico Académico (2CA), Braga, , Portugal
CHUC - Centro Hospitalar e Universitário de Coimbra, EPE, Coimbra, , Portugal
CHLC, EPE - Hospital de São José, Lisboa, , Portugal
CHLO, EPE - Hospital Egas Moniz, Lisboa, , Portugal
CHULN, EPE - Hospital de Santa Maria, Lisboa, , Portugal
Hospital Beatriz Ângelo, Loures, , Portugal
USLM, EPE - Hospital Pedro Hispano, Matosinhos, , Portugal
H. Santo António - Centro Hospitalar do Porto, Porto, , Portugal
Centro Hospitalar São João,EPE, Porto, , Portugal
Centro Hospitalar de Entre o Douro e Vouga, E.P.E. - Hospital de São Sebastião, Santa Maria da Feira, , Portugal
Interreg. Clinical & Diagnostic Center, Neurol. Dept., Kazan, Kazan, , Russian Federation
Reg.Clin.Hosp#1 na S.V.Ochapovskiy,Neurology#1 Dep,Krasnodar, Krasnodar, , Russian Federation
City Clin.Emergency Hosp of Kursk, Neurology Department No.2, Kursk, , Russian Federation
Clin.Hosp#2,na.Semashko,Russ.Railways,Restorative Med&Rehab., Moscow, , Russian Federation
CityClin.Hosp na I.V.Davydovsky of Dept of Healthcare Moscow, Moscow, , Russian Federation
Research&Clini Cent Neuropsychiatry Dep. Healthcare,Moscow, Moscow, , Russian Federation
City Clin.Hosp#1na N.I.Pirogov,Dept of Healthcare of Moscow, Moscow, , Russian Federation
Ltd liabilityCom.CityNeurologic Cntr Sibneiromed,Novosibirsk, Novosibirsk, , Russian Federation
Saratov State Med.Univ na V.I.Razumovsky,FacultyTherapy Clin, Saratov, , Russian Federation
Reg.State Instit.of Healthc.Smolensk Reg.Clin.Hosp,Neurology, Smolensk, , Russian Federation
Research Inst. of Emerg. Med., Vascul. Center,St. Petersburg, St. Petersburg, , Russian Federation
Military Medical Academy n.a. C. M. Kirov, St. Petersburg, St. Petersburg, , Russian Federation
Sverdlovsk Reg.Clin.Hosp.No.1, Yekaterinburg, , Russian Federation
Clinical Center of Serbia, Belgrade, , Serbia
Special Hosp.for Cerebrovascul.Disease,'Sveti Sava,Belgrade, Belgrade, , Serbia
Clinical Centre Nis, Nis, , Serbia
Clinical Center of Vojvodina, Novi Sad, , Serbia
National University Hospital, Singapore, , Singapore
Singapore General Hospital, Singapore, , Singapore
National Neuroscience Institute, Singapore, , Singapore
Faculty Hospital L. Pasteura, Kosice, Kosice, , Slovakia
Faculty Hospital Nitra, Nitra, , Slovakia
Instit.f.applicative Research in med.rehab.Dobrna, Dobrna, , Slovenia
Cardial d.o.o., Specialist out-patient unit, Ljubljana, Ljubljana, , Slovenia
Univ. Medical Center Maribor, Maribor, , Slovenia
University of Pretoria, Pretoria, , South Africa
Dr. Moodley and Dr. Sarvan, Tongaat, , South Africa
Hospital General Universitario de Albacete, Albacete, , Spain
Hospital del Mar, Barcelona, , Spain
Hospital Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Vall d'Hebron, Barcelona, , Spain
Hospital Universitari de Girona Doctor Josep Trueta, Girona, , Spain
Hospital Arnau de Vilanova, Lleida, , Spain
Hospital La Princesa, Madrid, , Spain
Hospital General Universitario Gregorio Marañón, Madrid, , Spain
Hospital Ramón y Cajal, Madrid, , Spain
Hospital Clínico San Carlos, Madrid, , Spain
Hospital La Paz, Madrid, , Spain
Hospital Son Espases, Palma de Mallorca, , Spain
Complejo Hospitalario de Navarra, Pamplona, , Spain
Hospital Universitario Donostia, San Sebastian, , Spain
Hospital Clínico de Santiago, Santiago de Compostela, , Spain
Hospital Virgen del Rocío, Sevilla, , Spain
Hospital Universitari Joan XXIII, Tarragona, , Spain
Hospital Mútua Terrassa, Tarrasa (Barcelona), , Spain
Hospital Clínico de Valencia, Valencia, , Spain
Hospital Clínico Universitario de Valladolid, Valladolid, , Spain
Sahlgrenska US, Göteborg, Göteborg, , Sweden
Sahlgrenska Universitetssjukhuset, Östra, Göteborg, , Sweden
Skaraborgs Sjukhus, Skövde, , Sweden
Karolinska Univ. sjukhuset, Stockholm, , Sweden
Karolinska Univ. sjukhuset, Stockholm, , Sweden
Danderyds Sjukhus, Stockholm, , Sweden
Canton Hospital Aarau, Neurology Dept., Stroke Center, Aarau, , Switzerland
University Hospital Basel, Basel, , Switzerland
Univ. Hospital Bern, Neurology Dept, Stroke Center, Bern, , Switzerland
CHUV - Centre hospitalier universitaire vaudois, Lausanne, , Switzerland
Regional Hospital Lugano,Neurocenter of Southern Switzerland, Lugano, , Switzerland
Kantonsspital St.Gallen, St. Gallen, , Switzerland
University Hosp. Zürich, Dept. of Neurology, Stroke Center, Zürich, , Switzerland
Chang-Hua Christian Hospital, Changhua, , Taiwan
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, , Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
Chi Mei Medical Center, Tainan,, , Taiwan
NCKUH, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Mackay Memorial Hospital, Taipei, , Taiwan
Cheng Hsin General Hospital, Taipei, , Taiwan
Taipe Veterans General Hospital, Taipei, , Taiwan
Tri-Service General Hospital, Taipei, , Taiwan
Chang Gung Memorial Hospital(TaoYuan), Taoyuan, , Taiwan
Chulalongkorn University, Bangkok, , Thailand
Ramathibodi Hospital, Bangkok, , Thailand
Siriraj Hospital, Bangkok, , Thailand
Lampang Hospital, Lampang, , Thailand
Ankara Universitesi Tip Fakultesi, Ankara, , Turkey
Hacettepe Universitesi Tip Fakultesi Noroloji A.B.D., Ankara, , Turkey
Gazi Universitesi Tip Fakultesi, Ankara, , Turkey
Eskisehir Osmangazi Universitesi Tip Fakultesi, Eskisehir, , Turkey
Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi, Istanbul, , Turkey
Istanbul Universitesi Istanbul Tip Fakultesi Noroloji A.B.D., Istanbul, , Turkey
Istanbul Universitesi Cerrahpasa Tip Fakultesi, Istanbul, , Turkey
Bakırkoy Dr. Sadi Konuk Egitim Ve Arastirma Hastanesi, Istanbul, , Turkey
Bakirkoy Prof. Dr. Mazhar Osman Ruh Sagligi ve Sinir Hastaliklari, Istanbul, , Turkey
Sisli Hamidiye Etfal Egitim ve Arastirma Hastanesi, Istanbul, , Turkey
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi, Istanbul, , Turkey
Dokuz Eylul Universitesi Tip Fakultesi Noroloji A.B.D., Izmir, , Turkey
Ondokuz Mayis Universitesi Tip Fakultesi, Samsun, , Turkey
Namik Kemal Universitesi Tip Fakultesi, Tekirdag, , Turkey
Bukovinian Med.Univ.Chernivtsi Reg.Psychiatric Hosp,Neurolog, Chernivtsi, , Ukraine
City Clinical Hospital No. 7, Kharkov, Kharkiv, , Ukraine
Instit.of Neurol,Psychiatry&Narcol,Vascul. Malformations Dep, Kharkiv, , Ukraine
Instit.of Gerontology na D.F.Chebotarev,Brain Vascular Path., Kyiv, , Ukraine
Lviv Regional Clinical Hospital, Lviv, Lviv, , Ukraine
Ternopil State Med.Univ.na Gorbachevskiy,Neurology Dept N3, Ternopil, , Ukraine
Vinnitsia Reg.Psychoneurol.Hosp.na Yushchenko,Dept.N3,Neurol, Vinnitsia, , Ukraine
Zhytomyr Reg.ClinHosp na Gerbachevskiy RegCouncil,Neurol.Dep, Zhytomyr, , Ukraine
Name: Boehringer Ingelheim
Affiliation: Boehringer Ingelheim
Role: STUDY_CHAIR