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Spots Global Cancer Trial Database for CD4-specific CAR T Cells (CD4 CAR T Cells) for Relapsed/Refractory T Cell Malignancies

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: CD4-specific CAR T Cells (CD4 CAR T Cells) for Relapsed/Refractory T Cell Malignancies

Official Title: CD4-specific CAR T Cells (CD4 CAR T Cells) for Relapsed/Refractory T Cell Malignancies

Study ID: NCT04162340

Interventions

CD4 CAR T cells

Study Description

Brief Summary: This is a phase I, interventional, single arm, open label, treatment study to evaluate the safety and tolerability of CD4 CAR T cells in patients with relapsed and/or refractory T cell lymphoma.

Detailed Description: CD4-specific CAR is a chimeric antigen receptor immunotherapy treatment designed to treat lymphoma/leukemia expressing CD4 antigen. CD4+ T cell lymphomas are a subset of leukemias and lymphomas that are positive for the surface protein CD4. The purpose of this study is to evaluate the efficacy and safety of CD4 CAR T cells.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Peking University Shenzhen Hospital, Shenzhen, Guangdong, China

Chengdu Military General Hospital, Chengdu, Sichuan, China

Contact Details

Name: Hongyu Zhang, MD/PhD

Affiliation: Peking University Shenzhen Hospital, China

Role: PRINCIPAL_INVESTIGATOR

Name: Fang Liu, MD/PhD

Affiliation: Chengdu Military Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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