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Spots Global Cancer Trial Database for Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms (IMG-7289-CTP-202/MK-3543-005)

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Trial Identification

Brief Title: Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms (IMG-7289-CTP-202/MK-3543-005)

Official Title: A Multi-Center, Open Label, Extension Study Evaluating the Safety and Efficacy of Bomedemstat for the Treatment of Patients With Myeloproliferative Neoplasms (MPNs) Enrolled in a Prior Bomedemstat Clinical Study

Study ID: NCT05223920

Interventions

Bomedemstat

Study Description

Brief Summary: This is a multi-center, open-label extension study to assess the long-term safety and efficacy of bomedemstat (MK-3543, formerly called IMG-7289) administered orally once daily in participants with an MPN who participated in a prior bomedemstat study such as, but not limited to, IMG-7289-CTP-102 and IMG-7289-CTP-201 (referred to hereafter as 'feeder studies').

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Miami Leonard M. Miller, Miami, Florida, United States

University of Michigan, Ann Arbor, Michigan, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

UMPC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

Fred Hutchinson Cancer Center, Seattle, Washington, United States

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

Royal North Shore Hospital, Saint Leonards, New South Wales, Australia

Gold Coast Hospital and Health Service, Southport, Queensland, Australia

Royal Adelaide Hospital, Adelaide, South Australia, Australia

Universittsklinikum Essen, Essen, , Germany

Queen Mary Hospital, Hong Kong, , Hong Kong

Ospedale di Circolo-a Fondazione Macchi, Varese, VA, Italy

Azienda Ospedaliera SS. Antonio, Alessandria, , Italy

Azienda Ospedaliero-Universitaria Careggi - S.O.D. Ematologia (CRIMM), Firenze, , Italy

Azienda Ospedaliero Universitaria di Bologna, Pavia, , Italy

Middlemore Clinical Trials, Papatoetoe, Aukland, New Zealand

Waitemata District Health Board, Takapuna, Aukland, New Zealand

University College London Hospitals NHS Foundation Trust, London, , United Kingdom

Guy's and Saint Thomas' NHS Foundation Trus, London, , United Kingdom

Contact Details

Name: Medical Director

Affiliation: Merck Sharp & Dohme LLC

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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