Spots Global Cancer Trial Database for IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients
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Trial Identification
Brief Title: IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients
Official Title: Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients
Study ID: NCT01398085
Conditions
Interventions
Study Description
Brief Summary: IoN is a phase II/ III trial that will look to ascertain whether or not radio-iodine ablation is necessary for low risk differentiated thyroid cancer patients.
Detailed Description: Phase II: to determine if recruitment into a phase III trial is feasible, with a target of 10 patients per month during a minimum of 6 months (evaluated within months 7-18 of the trial). Phase III: to determine whether the 5-year disease-free survival rate among patients who do not have routine Radioactive iodine (RAI) ablation is non-inferior to those who do.
Eligibility
Minimum Age: 16 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University Hospitals Birmingham NHS Foundation Trust, Birmingham, , United Kingdom
Brighton and Sussex University Hospitals NHS Trust, Brighton, , United Kingdom
University Hospital Bristol NHS Foundation Trust, Bristol, , United Kingdom
Cambridge University Hospitals NHS Foundation Trust, Cambridge, , United Kingdom
East Kent Hospitals University NHS Foundation Trust, Canterbury, , United Kingdom
Mid Essex Hospitals Services NHS Trust, Chelmsford, , United Kingdom
Gloucestershire Hospitals NHS Trust, Cheltenham, , United Kingdom
Royal Derby hospital NHS foundation trust, Derby, , United Kingdom
NHS Lothian, Edinburgh, , United Kingdom
Royal Devon and Exeter NHS Trust, Exeter, , United Kingdom
Glasgow and Clyde NHS Trust, Glasgow, , United Kingdom
The Royal Surrey County Hospital NHS Foundation Trust, Guildford, , United Kingdom
Ipswich Hospital NHS Trust, Ipswich, , United Kingdom
Leeds Teaching Hospitals NHS Trust, Leeds, , United Kingdom
University Hospitals of Leicester NHS Trust, Leicester, , United Kingdom
Royal Marsden NHS Foundation Trust, London, , United Kingdom
Imperial College Healthcare NHS Trust, London, , United Kingdom
Barts Health NHS Trust, London, , United Kingdom
Guys and St Thomas' NHS Foundation Trust, London, , United Kingdom
University College London Hospitals NHS Foundation Trust, London, , United Kingdom
Maidstone and Tunbridge Wells NHS Trust, Maidstone, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
South Tees Hospitals NHS Trust, Middlesbrough, , United Kingdom
Velindre NHS Trust, Nantgarw, , United Kingdom
Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, , United Kingdom
Norfolk and Norwich University Hospitals NHS Trust, Norwich, , United Kingdom
Nottingham University Hospitals NHS Trust, Nottingham, , United Kingdom
Portsmouth Hospitals NHS Trust, Portsmouth, , United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, , United Kingdom
Southend University Hospitals NHS Trust, Southend, , United Kingdom
East and North Herts, Stevenage, , United Kingdom
Royal Wolverhampton NHS Trust, Wolverhampton, , United Kingdom
Contact Details
Name: Ujjal Mallick, MBBS, Master of Surgery, FRCR
Affiliation: Newcastle-upon-Tyne Hospitals NHS Foundation Trust
Role: PRINCIPAL_INVESTIGATOR
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