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Brief Title: An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer
Official Title: An International, Phase III, Randomized, Double-Blinded, Placebo-Controlled, Multi-Center Study to Assess the Efficacy of ZD6474 (ZACTIMATM) Versus Placebo in Subjects With Unresectable Locally Advanced or Metastatic Medullary Thyroid Cancer
Study ID: NCT00410761
Brief Summary: The purpose of this study is to learn how hereditary or sporadic medullary thyroid cancer patients, treated with ZD6474, react to the drug, what happens to ZD6474 in the human body, about the side effects of ZD6474, and if ZD6474 can decrease or prevent the growth of tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Investigational Site Number 3, Little Rock, Arkansas, United States
Investigational Site Number 8, San Francisco, California, United States
Investigational Site Number 9, Aurora, Colorado, United States
Investigational Site Number 11, New Haven, Connecticut, United States
Investigational Site Number 15, Jacksonville, Florida, United States
Investigational Site Number 18, Chicago, Illinois, United States
Investigational Site Number 17, Lexington, Kentucky, United States
Investigational Site Number 2, Boston, Massachusetts, United States
Investigational Site Number 7, Detroit, Michigan, United States
Investigational Site Number 14, Rochester, Minnesota, United States
Investigational Site Number 10, Saint Louis, Missouri, United States
Investigational Site Number 6, Cincinnati, Ohio, United States
Investigational Site Number 22, Portland, Oregon, United States
Investigational Site Number 19, Charleston, South Carolina, United States
Investigational Site Number 13, Houston, Texas, United States
Investigational Site Number 21, Burlington, Vermont, United States
Investigational Site Number 1001, St Leonards, , Australia
Investigational Site Number 1901, Wien, , Austria
Investigational Site Number 1101, Bruxelles, , Belgium
Investigational Site Number 1102, Leuven, , Belgium
Investigational Site Number 2301, Porto Alegre, , Brazil
Investigational Site Number 2302, Ribeirão Preto, , Brazil
Investigational Site Number 1203, Calgary, , Canada
Investigational Site Number 1202, London, , Canada
Investigational Site Number 1201, Moncton, , Canada
Investigational Site Number 1204, Sherbrooke, , Canada
Investigational Site Number 1205, Toronto, , Canada
Investigational Site Number 3601, Praha 5, , Czechia
Investigational Site Number 2701, Odense C, , Denmark
Investigational Site Number 2802, BORDEAUX Cedex, , France
Investigational Site Number 2803, LYON Cedex 8, , France
Investigational Site Number 2801, Villejuif, , France
Investigational Site Number 2002, Essen, , Germany
Investigational Site Number 2001, Halle, , Germany
Investigational Site Number 2005, Würzburg, , Germany
Investigational Site Number 1601, Pécs, , Hungary
Investigational Site Number 1401, Mumbai, , India
Investigational Site Number 1402, Vellore, , India
Investigational Site Number 2506, Catania, , Italy
Investigational Site Number 2502, Milano, , Italy
Investigational Site Number 2503, Napoli, , Italy
Investigational Site Number 2501, Pisa, , Italy
Investigational Site Number 2505, Roma, , Italy
Investigational Site Number 2504, Siena, , Italy
Investigational Site Number 1501, Seoul, , Korea, Republic of
Investigational Site Number 2403, Cd. Madero, , Mexico
Investigational Site Number 2402, Mexico City, , Mexico
Investigational Site Number 2404, México, , Mexico
Investigational Site Number 2902, Groningen, , Netherlands
Investigational Site Number 2901, Utrecht, , Netherlands
Investigational Site Number 1701, Gliwice, , Poland
Investigational Site Number 1702, Poznan, , Poland
Investigational Site Number 1703, Warszawa, , Poland
Investigational Site Number 2602, Coimbra, , Portugal
Investigational Site Number 2601, Lisboa, , Portugal
Investigational Site Number 1801, Bucarest, , Romania
Investigational Site Number 3301, Obninsk, , Russian Federation
Investigational Site Number 3402, Belgrade, , Serbia
Investigational Site Number 3401, Belgrad, , Serbia
Investigational Site Number 3003, Madrid, , Spain
Investigational Site Number 3001, Madrid, , Spain
Investigational Site Number 3002, Pamplona, , Spain
Investigational Site Number 3102, Stockholm, , Sweden
Investigational Site Number 3101, Uppsala, , Sweden
Investigational Site Number 2101, Basel, , Switzerland
Investigational Site Number 2102, Bern, , Switzerland
Name: Clinical Sciences & Operations
Affiliation: Sanofi
Role: STUDY_DIRECTOR