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Brief Title: An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors
Official Title: RIFTOS MKI - Radioactive Iodine reFractory Asymptomatic Patients in Differentiated Thyroid Cancer - an Observational Study to Assess the Use of Multikinase Inhibitors
Study ID: NCT02303444
Brief Summary: The purpose of the study was to assess the use of Multikinase Inhibitors (MKIs) in the treatment of patients with a progressive differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAI) who do not have any symptoms.
Detailed Description: The primary objective of this study was to compare time to symptomatic progression (TTSP) from study entry in asymptomatic patients with RAI-refractory progressive DTC for whom there is a decision to initiate MKIs at study entry with that of asymptomatic patients with RAI-refractory progressive DTC for whom there is a decision to not initiate MKIs at study entry.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Birmingham, Alabama, United States
, Los Angeles, California, United States
, Torrance, California, United States
, Aurora, Colorado, United States
, Washington, District of Columbia, United States
, Plantation, Florida, United States
, Atlanta, Georgia, United States
, Honolulu, Hawaii, United States
, Chicago, Illinois, United States
, New Orleans, Louisiana, United States
, Boston, Massachusetts, United States
, Ann Arbor, Michigan, United States
, Bronx, New York, United States
, Durham, North Carolina, United States
, Philadelphia, Pennsylvania, United States
, Dallas, Texas, United States
, Multiple Locations, , Algeria
, Multiple Locations, , Argentina
, Multiple Locations, , Brazil
, Multiple Locations, , Egypt
, Multiple Locations, , France
, Multiple Locations, , Germany
, Multiple Locations, , Greece
, Multiple Locations, , India
, Multiple Locations, , Japan
, Multiple Locations, , Lebanon
, Multiple Locations, , Mexico
, Multiple Locations, , Netherlands
, Multiple Locations, , Philippines
, Multiple Locations, , Russian Federation
, Multiple Locations, , Saudi Arabia
, Multiple Locations, , Spain
, Multiple Locations, , Taiwan
, Multiple Locations, , Turkey
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR