Spots Global Cancer Trial Database for PACE4 in Thyroid Cancer
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Trial Identification
Brief Title: PACE4 in Thyroid Cancer
Official Title: Evaluation of PACE4 Isoforms as Biomarkers in Thyroid Cancer
Study ID: NCT03160482
Conditions
Interventions
Study Description
Brief Summary: The investigation of thyroid nodules is limited by the fact that up to 49% of the fine needle aspirations (FNA) performed are of "indeterminate cytological signification". Moreover, no fully reliable molecular marker for thyroid cancer have been described. The goal of this project is to study the expression of a specific kind of protein convertase in benign and in malignant thyroid nodules to determine its potential as a biomarker.
Detailed Description: Patients that underwent thyroidectomy at the CIUSSS de l'Estrie-CHUS will be recruited and classified according to the pathological diagnosis. An immunohistochemistry technique, developed and calibrated for the specific protein convertase studied, will be undertaken. Results will be interpreted by a specialized pathologist.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
CIUSSS de l'Estrie - CHUS, Sherbrooke, Quebec, Canada
Contact Details
Name: Robert Day, PhD
Affiliation: Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Role: PRINCIPAL_INVESTIGATOR
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