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Brief Title: Photon Therapy Versus Proton Therapy in Early Tonsil Cancer.
Official Title: Photon Therapy Versus Proton Therapy in Early Tonsil Cancer.
Study ID: NCT03829033
Brief Summary: In this trial, patients with early squamous cell carcinoma of the tonsil with clinical stage T1-2 (p16-positive or p16-negative) N0-1 (p16-positive)/N0-N2b (p16-negative) according to American Joint Committee on Cancer (AJCC) 8th edition, aimed for unimodal and ipsilateral treatment with radiotherapy with curative intent will be included. The patients will be randomized to in a 1:1 ratio to receive radiotherapy with either photons (conventional radiotherapy) versus radiotherapy with protons.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Gävle Hospital, Gävle, , Sweden
Sahlgrenska University Hospital, Göteborg, , Sweden
Jönköping Hospital, Jönköping, , Sweden
Karlstad Hospital, Karlstad, , Sweden
Linköping University Hospital, Linköping, , Sweden
Lund University Hospital, Lund, , Sweden
Karolinska University Hospital, Stockholm, , Sweden
University Hospital, Umeå, , Sweden
Scandion clinic, Uppsala, , Sweden
Uppsala Accademical Hospital, Uppsala, , Sweden
Västmanlands Hospital, Västerås, , Sweden
Örebro University Hospital, Örebro, , Sweden
Name: Maria Gebre-Medhin, MD
Affiliation: Lund University Hospiyal
Role: PRINCIPAL_INVESTIGATOR