Spots Global Cancer Trial Database for Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer
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Trial Identification
Brief Title: Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer
Official Title: Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer
Study ID: NCT03639948
Conditions
Study Description
Brief Summary: The standard treatment for women with stage I, II, and III triple-negative breast cancer (TNBC) includes chemotherapy and surgery, with or without radiation therapy. However, because TNBC is usually more aggressive, harder to treat, and more likely to come back, it is associated with poor long-term outcomes (survival rates) when compared to other types of breast cancer. Therefore, researchers are studying how new drugs and treatment combinations can improve the outcome of patients with TNBC. This study will test effectiveness of immune therapy (Pembrolizumab is an "immunotherapy" that is expected to work with the body's immune system to help fight cancer) in combination with chemotherapy given before surgery.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
The University of Kansas Cancer Center (KUCC), Fairway, Kansas, United States
The University of Kansas Cancer Center, West Clinic, Kansas City, Kansas, United States
The University of Kansas Cancer Center, Westwood Campus, Kansas City, Kansas, United States
University of Kansas Cancer Center, Kansas City, Kansas, United States
The University of Kansas Cancer Center, Overland Park Clinic, Overland Park, Kansas, United States
The University of Kansas Cancer Center, North Clinic, Kansas City, Missouri, United States
The University of Kansas Cancer Center, Lee's Summit Clinic, Lee's Summit, Missouri, United States
The University of Kansas Medical Center, North Kansas City, Missouri, United States
Texas Oncology- Baylor, Dallas, Texas, United States
Contact Details
Name: Priyanka Sharma, MD
Affiliation: The University of Kansas Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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