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Brief Title: Proton Radiotherapy for Recurrent Tumors
Official Title: Retreatment of Recurrent Tumors Using Proton Therapy
Study ID: NCT01126476
Brief Summary: The purpose of this study is to determine the feasibility of using proton radiotherapy for reirradiation of recurrent malignancies.
Detailed Description: Patients will be stratified by treatment site (Head and Neck, Thorax, Abdomen, Pelvis, Extremities) and by treatment volume (low volume, high volume) for a total of 10 strata. This study will be done in two phases. In the first phase, feasibility will be established using the primary objectives set below. The second phase will begin no earlier than 90 days after the last patient in the initial phase has completed treatment in each strata and once feasibility has been verified. The secondary objectives will serve as the objectives for the second phase of the study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
ProCure Proton Therapy Center, Warrenville, Illinois, United States
Procure, Oklahoma City, Oklahoma, United States
Abamson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Name: John Plastaras, MD, PhD
Affiliation: Abramson Cancer Center at Penn Medicine
Role: PRINCIPAL_INVESTIGATOR
Name: Marcio Fagundes, MD
Affiliation: Procure, Oklahoma City, OK
Role: PRINCIPAL_INVESTIGATOR
Name: William F. Hartsell, MD
Affiliation: ProCure Proton Therapy Center, Warrenville, IL
Role: PRINCIPAL_INVESTIGATOR