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Brief Title: Study of Dasatinib in Patients With Advanced Solid Tumors
Official Title: Phase I Study to Evaluate the Effect of Ketoconazole on the Pharmacokinetics of Dasatinib and the Effect of Dasatinib on Pharmacodynamic Markers in Patients With Advanced Solid Tumors
Study ID: NCT00162214
Brief Summary: The purpose of Segment 1 of the study is to determine the effect of ketoconazole on dasatinib. The purpose of Segment 2 is to learn how dasatinib affects tumor growth in patients with advanced solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Lee S. Rosen M.D., Santa Monica, California, United States
H. Lee Moffitt Cancer Center, Tampa, Florida, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Md Anderson Cancer Center, Houston, Texas, United States