⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for DESTINY Breast Respond HER2-low Europe

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: DESTINY Breast Respond HER2-low Europe

Official Title: A Prospective, Non-interventional Study (NIS) With Trastuzumab Deruxtecan For Patients With HER2-low Expressing Unresectable and/or Metastatic Breast Cancer Accompanied By a Disease Registry of Patients Treated With Conventional Chemotherapy (DESTINY Breast Respond HER2-low Europe)

Study ID: NCT05945732

Study Description

Brief Summary: Trastuzumab deruxtecan (T-DXd) as monotherapy is indicated for the treatment of adult patients with unresectable or metastatic HER2-low breast cancer who have received prior chemotherapy in the metastatic setting or developed disease recurrence during or within 6 months of completing adjuvant chemotherapy.

Detailed Description: This non-interventional study will investigate the effectiveness withT-DXd, the demographic and clinical characteristics of the patients, treatment patterns, tolerability, management of adverse drug reactions (ADRs), and patient experience of T-DXd in patients with HER2-low unresectable and/or metastatic breast cancer. Patients will be treated according to the proposed indication statement in the Summary of Product Characteristics (SmPC). No drug product will be administered as part of this study. Data on conventional chemotherapy (i.e., including but not limited to capecitabine, eribulin, gemcitabine, paclitaxel and nab-paclitaxel) will also be collected in a disease registry part of the study.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Medizinische Universität Graz, Graz, , Austria

Medizinische Universität Graz, Graz, , Austria

Medizinische Universität Innsbruck, Innsbruck, , Austria

Ordensklinikum Linz GmbH Barmherzige Schwestern, Linz, , Austria

Interne II, LKH Feldkirch, Rankweil, , Austria

KH der Barmherzigen Brüder Salzburg, Salzburg, , Austria

Uniklinikum Salzburg, Salzburg, , Austria

Salzkammergut Klinikum Vöcklabruck, Vöcklabruck, , Austria

Klinikum Wels-Grieskirchen GmbH, Wels, , Austria

Landesklinikum Wiener Neustadt, Wiener Neustadt, , Austria

Medical University of Vienna, Wien, , Austria

Medizinische Universität Wien, Wien, , Austria

Krankenhaus Hietzing, Wien, , Austria

ASZ Aalst, Aalst, , Belgium

Imeldaziekenhuis Bonheiden, Bonheiden, , Belgium

AZ Klina, Brasschaat, , Belgium

AZ Sint-Jan Brugge av, Brugge, , Belgium

CHU Brugmann, Brussels, , Belgium

Cliniques universitaires Saint-Luc, Brussels, , Belgium

Chu Helora- Hôpital de La Louvière- site Jolimont, Haine Saint Paul, , Belgium

CHU Tivoli, La Louviere, , Belgium

Hôpital de la Citadelle, Liege, , Belgium

CHU UCL Namur/Site Sainte Elisabeth, Namur, , Belgium

Clinique Saint Pierre Ottignies, Ottignies, , Belgium

VITAZ, Sint-Niklaas, , Belgium

CHR Verviers East Belgium, Verviers, , Belgium

Aalborg Universitetshospital, Syd, Aalborg, , Denmark

Aarhus University Hospital, Aarhus N, , Denmark

Sygehus Sønderjylland, Sønderborg, Sønderborg, , Denmark

CHU Amiens Picardie, Amiens, , France

Clinique de l'Europe, Amiens, , France

Institut du Cancer Avignon Provence, Avignon, , France

CH Cote Basque, Bayonne, , France

Clinique Belharra, Bayonne, , France

Chu Jean Minjoz Besancon, Besançon, , France

Clinique Tivoli-Ducos, Bordeaux, , France

Centre hospitalier Fleyriat, Bourg-en-Bresse, , France

Centre Francois Baclesse, Caen, , France

Centre Hospitalier William Morey, Chalon-sur-Saône, , France

Pole Sante Leonard De Vinci, Chambray-lès-Tours, , France

CH Metropole Savoie, Chambéry, , France

CH Cholet, Cholet, , France

Centre Jean Perrin, Clermont-Ferrand, , France

Polyclinique St Côme, Compiègne, , France

Hôpital Henri Mondor, Créteil, , France

Centre Léonard de Vinci, Dechy, , France

Centre Georges Francois Leclerc, Dijon, , France

CHU Martinique, Fort De France Cedex, , France

CHI Frejus Saint Raphael, Fréjus, , France

Groupe Hospitalier Mutualiste (GHM) de Grenoble - Institut Daniel Hollard (IDH), Grenoble, , France

Polyclinique De Blois, La Chaussee Saint Victor, , France

La Tronche - CHU Grenoble, La Tronche, , France

Centre de cancerologie de la Sarthe, Le Mans, , France

Centre Hospitalier Emile Roux, Le Puy-en-Velay, , France

Centre Oscar Lambret, Lille, , France

CHU Lille, Lille, , France

Hôpital Prive Le Bois, Lille, , France

Hospices Civils De Lyon, Lyon, , France

Hôpital-Clinique Claude Bernard, Metz, , France

GH Havre, Montivilliers, , France

Clinique Clementville, Montpellier, , France

Groupe Hospitalier privé Ambroise Pare Hartmann, Neuilly-sur-Seine, , France

Hopital Americain de Paris, Neuilly-sur-Seine, , France

Centre Antoine Lacassagne, Nice, , France

Centre Hospitalier de Niort, Niort, , France

Centre Médical ONCOGARD, NÎMES Cedex 9, , France

Institut Curie, Paris, , France

Groupement Hospitalier Diaconesses Croix Saint Simon, Paris, , France

Hopital Europeen Georges Pompidou, Paris, , France

Hôpital Saint Joseph, Paris, , France

CHU Poitiers, Poitiers, , France

Institut Godinot, Reims, , France

Polyclinique Courlancy, Reims, , France

Clinique Saint Hilaire, Rouen, , France

Clinique Mathilde, Rouen, , France

Saint Cloud -Rene Huguenin Institut Curie, Saint-Cloud, , France

CHU Réunion Site Sud, Saint-Paul, , France

Institut De Cancerologie Paris Nord, Sarcelles, , France

Centre Hospitalier de Sens, Sens Cédex, , France

Hôpital Foch, Suresnes, , France

CHR Metz Thionville, Thionville, , France

HIA Sainte-Anne, Toulon, , France

Centre Hospitalier de Troyes, Troyes, , France

Hopital Prive Drome Ardeche, Valence, , France

Nouvelle Clinique Des Dentellières, Valenciennes, , France

Institut De Cancerologie De Lorraine, Vandœuvre-lès-Nancy, , France

Médipôle Hôpital Mutualiste, Villeurbanne, , France

Azienda Ospedaliera di Alessandria, Alessandria, , Italy

Ospedale SS Annunziata, Chieti, , Italy

Ospedale Citta' di Castello USL Umbria 1, Città di Castello, , Italy

Ospedale San Giuseppe - Azienda USL Toscana Centro, Empoli, , Italy

ASST Lecco - PO "Alessandro Manzoni", Lecco, , Italy

AULSS 9 Scaligera - Ospedale Mater Salutis, Legnago, , Italy

Ospedale Generale Provinciale di Macerata, Macerata, , Italy

Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS, Meldola, , Italy

Fondazione IRCCS San Gerardo dei Tintori, Monza, , Italy

AOU Federico II, Napoli, , Italy

AOU Maggiore della Carità di Novara, Novara, , Italy

IOV - Istituto Oncologico Veneto - IRCCS, Padova, , Italy

ARNAS Ospedale Civico e Benfratelli, Palermo, , Italy

Fondazione IRCCS Policlinico San Matteo, Pavia, , Italy

AO Regionale San Carlo, Potenza, , Italy

ASL RM 2 Ospedale Pertini, Roma, , Italy

AO San Giovanni Addolorata, Roma, , Italy

AOU "San Giovanni di Dio e Ruggi d'Aragona", Salerno, , Italy

Ospedale San Vincenzo, Taormina, , Italy

AOU Città della Salute e della Scienza di Torino - Ospedale Molinette, Torino, , Italy

AO Ordine Mauriziano, Torino, , Italy

ASUFC Udine - Santa Maria della Misericordia, Udine, , Italy

ASST Sette Laghi "Ospedale di Circolo e Fondazione Macchi ", Varese, , Italy

Universitetssjukhuset Nord-Norge, Tromsø, , Norway

Hospital Clinico Universitario de Albacete, Albacete, , Spain

Hospital Universitario de La Ribera, Alzira, , Spain

Hospital Universitario de Basurto, Bilbao, , Spain

Hospital Universitario Reina Sofia, Cordoba, , Spain

Hospital Universitario San Pedro de Alcántara, Cáceres, , Spain

Hospital Universitario de Puerto Real, Cádiz, , Spain

Hospital Clinico Universitario de Granada (PTS), Granada, , Spain

Hospital Universitario de Canarias, La Laguna, , Spain

Complejo Asistencial Universitario de León, León, , Spain

Hospital Universitario Lucus Augusti, Lugo, , Spain

Hospital MD Anderson Cancer Center, Madrid, , Spain

Hospital Universitario Ramón y Cajal, Madrid, , Spain

Hospital Clínico Universitario San Carlos, Madrid, , Spain

Hospital Universitario 12 de Octubre, Madrid, , Spain

Hospital de Getafe, Madrid, , Spain

Hospital Virgen Arrixaca de Murcia, Murcia, , Spain

Hospital Universitario Central de Asturias, Oviedo, , Spain

Hospital Son Espases, Palma de Mallorca, , Spain

Hospital Son Llatzer, Palma, , Spain

Hospital de Pontevedra, Pontevedra, , Spain

Hospital San Joan de Reus, Reus, , Spain

Hospital Universitari Parc Taulí, Sabadell, , Spain

Hospital General de Catalunya, Sant Cugat del Vallès, , Spain

Hospital Universitario Marqués de Valdecilla, Santander, , Spain

Hospital Universitario General de Valencia, Valencia, , Spain

Hospital Clínico de Valladolid, Valladolid, , Spain

Complejo Hospitalario Universitario De Vigo, Vigo Pontevedra, , Spain

Capio St Görans sjukhus, Stockholm, , Sweden

Bröstcentrum, Karolinska Universitetssjukhuset Solna, Stockholm, , Sweden

Department of Oncology, Västerås, Västerås, , Sweden

Department of Oncology, Örebro University Hospital, Örebro, , Sweden

Kantonsspital Baden, Baden, , Switzerland

Spital Thurgau AG - Kantonsspital Frauenfeld, Frauenfeld, , Switzerland

Centre du sein Fribourg, Fribourg, , Switzerland

Clinique Generale-Beaulieu / Clinique de Genolier, Genève, , Switzerland

CHUV, Lausanne, , Switzerland

Hôpital du Valais Sion, Sion, , Switzerland

ZIO AG, Zürich, , Switzerland

Contact Details

Name: Global Team Leader

Affiliation: Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: