Spots Global Cancer Trial Database for Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases

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Trial Identification

Brief Title: Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases

Official Title: Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases: A Multicentre, Prospective, Open-label, Single-arm Trial

Study ID: NCT05692037

Conditions

Unresectable Colorectal Liver Metastases

Interventions

Selective internal radiation therapy (SIRT) with yttrium-90 carbon microspheres

Study Description

Brief Summary: To evaluate the efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases

Detailed Description: The efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases remain unknown. This multicentre, prospective, open-label, single-arm trial is designed to evaluate the safety and efficacy of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases. The primary endpoints are the progression-free survival rates of liver target lesions. While the secondary endpoints include the safety, tumor control, and the distribution characteristics of yttrium-90 carbon microspheres.