Spots Global Cancer Trial Database for Yttrium-90 Carbon Microspheres in Patients With Unresectable Hepatocellular Carcinoma

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Trial Identification

Brief Title: Yttrium-90 Carbon Microspheres in Patients With Unresectable Hepatocellular Carcinoma

Official Title: Yttrium-90 Carbon Microspheres in Patients With Unresectable Hepatocellular Carcinoma: A Multicentre, Prospective, Open-label, Single-arm Trial

Study ID: NCT05957640

Conditions

Unresectable Hepatocellular Carcinoma

Interventions

Yttrium-90 carbon microspheres SIRT

Study Description

Brief Summary: To evaluate the efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable hepatocellular carcinoma

Detailed Description: The efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable hepatocellular carcinoma remain unknown. This multicentre, prospective, open-label, single-arm trial is designed to evaluate the safety and efficacy of yttrium-90 carbon microspheres in patients with hepatocellular carcinoma. The primary endpoints are safety and local objective response rate of liver target lesions. While the secondary endpoints include the time to progression, progression-free survival rates, disease control rates, duration of response, quality of life and the distribution characteristics of yttrium-90 carbon microspheres.