Spots Global Cancer Trial Database for TACE Study-Liver Embolization Perfusion (VGH Radiology LIU)

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Trial Identification

Brief Title: TACE Study-Liver Embolization Perfusion (VGH Radiology LIU)

Official Title: Utilizing Intraprocedural Flow and Perfusion Dynamics as a Predictor of Response in Patients With Unresectable Hepatocellular Carcinoma Undergoing Chemoembolization and Radioembolization (Y90) "Liver Embolization Perfusion TACE Study (Version 1.0) EPTS 2013-1.0"

Study ID: NCT02093104

Conditions

Unresectable Hepatocellular Carcinoma

Undergoing Chemoembolization and Radioembolization

Interventions

Study Description

Brief Summary: The purpose of this research study is to evaluate the quantitative information of utilizing C-arm systems in liver tumor care in hopes this potential clinical combination of imaging could aid in diagnosis and evaluation of tumor therapy.

Detailed Description: Blood flow imaging for liver tumors is normally carried out using clinical Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) systems prior to going to the cath lab. This study aims to determine if measuring flow using a C-arm system and/or CT perfusion can be used to improve diagnosis and evaluation of liver tumors. The major difference between C-arm CT systems and clinical CT systems is the difference in imaging speed. We have developed a new approach that should allow us to overcome this speed limitation. The major difference between conventional CT versus CT perfusion is the obtaining of an extra series of images. CT perfusion results in an increase in the amount of radiation exposure during the CT scan that measures the blood flow of the targeted tumor; however, CT perfusion is much faster than conventional CT. Prospective participants are being invited to the study because part of the treatment towards the tumour therapy involves obtaining an angiogram.