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Spots Global Cancer Trial Database for A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)

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Trial Identification

Brief Title: A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)

Official Title: A Randomized Open-Label Phase 3 Trial of BMS-936558 (Nivolumab) Versus Investigator's Choice in Advanced (Unresectable or Metastatic) Melanoma Patients Progressing Post Anti-CTLA-4 Therapy

Study ID: NCT01721746

Study Description

Brief Summary: The purpose of the study is to estimate the response rate and compare overall survival of patients taking BMS-936558 to those taking study physician's choice of either Dacarbazine or Carboplatin and Paclitaxel

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic, Phoenix, Arizona, United States

UCSD Moores Cancer Center, La Jolla, California, United States

The Angeles Clinic & Research Institute, Los Angeles, California, United States

University Of California - Los Angeles, Los Angeles, California, United States

San Francisco Oncology Associates, San Francciso, California, United States

UCSF Comprehensive Cancer Center, San Francisco, California, United States

University Of Colorado, Aurora, Colorado, United States

Yale University School Of Medicine, New Haven, Connecticut, United States

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States

Orlando Health, Inc, Orlando, Florida, United States

H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States

Winship Cancer Institute, Atlanta, Georgia, United States

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

University Of Michigan Health System, Ann Arbor, Michigan, United States

Karmanos Cancer Institute, Detroit, Michigan, United States

Allina Health, Minneapolis, Minnesota, United States

Washington University School Of Medicine, Saint Louis, Missouri, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

NYU Clinical Cancer Center, New York, New York, United States

MSKCC Clinical Laboratory at Nassau, New York, New York, United States

Levine Cancer Institute, Charlotte, North Carolina, United States

Duke University Medical Center, Durham, North Carolina, United States

University Hospitals, Cleveland, Ohio, United States

Providence Oncology And Hematology, Portland, Oregon, United States

Network Office of Research and Innovation, Allentown, Pennsylvania, United States

St. Luke'S Health System, Allentown, Pennsylvania, United States

Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

Tennessee Oncology, PLLC, Nashville, Tennessee, United States

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

Huntsman Cancer Institute, Salt Lake City, Utah, United States

Local Institution, Innsbruck, , Austria

Local Institution, Wien, , Austria

Local Institution, Brussels, , Belgium

Local Institution, Bruxelles, , Belgium

Local Institution, Edegem, , Belgium

Local Institution, Leuven, , Belgium

Local Institution, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution, Rio de Janeiro, , Brazil

Local Institution, Sao Paulo, , Brazil

Cross Cancer Institute, Edmonton, Alberta, Canada

Princess Margaret Hospital, Toronto, Ontario, Canada

CHUM, Montreal, Quebec, Canada

Sir Mortimer B Davis - Jewish General Hospital, Montreal, Quebec, Canada

Aarhus Universitetshospital, Aarhus, , Denmark

Herlev Hospital, Herlev, , Denmark

Odense University Hospital, Odense, , Denmark

Local Institution, Clermont Ferrand, , France

Local Institution, Lille Cedex, , France

Hopital La Timone, Marseille, , France

Local Institution, Nantes Cedex 01, , France

Local Institution, Nice, , France

Local Institution, Paris, , France

Local Institution, Pierre Benite, , France

Local Institution, Villejuif, , France

Local Institution, Wuerzburg, Bayern, Germany

Local Institution, Buxtehude, , Germany

Local Institution, Dresden, , Germany

Local Institution, Essen, , Germany

Local Institution, Frankfurt am Main, , Germany

Local Institution, Hannover, , Germany

Local Institution, Heidelberg, , Germany

Local Institution, Kiel, , Germany

Local Institution, Luebeck, , Germany

Local Institution, Magdeburg, , Germany

Local Institution, Munich, , Germany

Local Institution, Tubingen, , Germany

Local Institution, Jerusalem, , Israel

Local Institution, Ramat Gan, , Israel

Local Institution, Bari, , Italy

Local Institution, Bergamo, , Italy

Local Institution, Genova, , Italy

Local Institution, Milano, , Italy

Local Institution, Milano, , Italy

Local Institution, Napoli, , Italy

Local Institution, Padova, , Italy

Local Institution, Roma, , Italy

Local Institution, Siena, , Italy

Local Institution, Amsterdam, , Netherlands

Local Institution, Groningen, , Netherlands

Local Institution, Maastricht, , Netherlands

Local Institution, Barcelona, , Spain

Local Institution, Barcelona, , Spain

Local Institution, Madrid, , Spain

Local Institution, Madrid, , Spain

Local Institution, Pamplona, , Spain

Local Institution, Valencia, , Spain

Local Institution, Lausanne, , Switzerland

Local Institution, Zuerich, , Switzerland

Local Institution, Manchester, Greater Manchester, United Kingdom

Local Institution, Southampton, Hampshire, United Kingdom

Local Institution, Oxford, Oxfordshire, United Kingdom

Local Institution, Newcastle Upon Tyne, Tyne And Wear, United Kingdom

Local Institution, London, , United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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