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Spots Global Cancer Trial Database for Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients

Official Title: The Clinical Research About the Therapeutic Effect and Safety of 10 Days Regimen With Single-agent of Decitabine for Elderly AML Patients

Study ID: NCT01633099

Interventions

Decitabine

Study Description

Brief Summary: The purpose of this study is to confirm the safety and the therapeutic effect of Decitabine in the treatment of elderly Acute Myeloid Leukemia (AML) patients.

Detailed Description: The outcome of the elderly AML patients is very poor. No obvious progress was achieved in this field. Decitabine is a kind of specific DNA methylation shift enzyme inhibitor. It can reverse the DNA methylation and induce the differentiation and apoptosis of the tumor cells. Recent studies about decitabine in the treatment for elderly AML patients had achieved inspiring results and indicated that low dose decitabine maybe a good choice for elderly AML patients. So in this research the investigators plan to evaluate the safety and the therapeutic effect of decitabine in the treatment of elderly AML patients.

Eligibility

Minimum Age: 60 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Contact Details

Name: Jianxiang Wang, MD

Affiliation: Institute of Hematology, Hospital of Blood Disease, Chinese Academy of Medical Sciences

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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