Spots Global Cancer Trial Database for A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract
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Trial Identification
Brief Title: A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract
Official Title: An Open Label, Single Arm, Multicenter, Safety Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract
Study ID: NCT02928406
Conditions
Interventions
Study Description
Brief Summary: This Phase IIIb, multicenter study will assess the safety of atezolizumab as second- to fourth-line treatment for participants with locally advanced or metastatic urothelial or non-urothelial cancer of the urinary tract in addition to evaluate the efficacy of atezolizumab and potential tumor biomarkers associated with atezolizumab.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Inst. Alexander Fleming; Oncologia, Buenos Aires, , Argentina
Hospital Aleman, Caba, , Argentina
Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, , Argentina
Canberra Hospital; Medical Oncology, Canberra, Australian Capital Territory, Australia
Macquarie University Hospital, Macquarie Park, New South Wales, Australia
Prince of Wales Hospital; Oncology, Randwick, New South Wales, Australia
Northern Cancer Institute, St Leonards, New South Wales, Australia
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales, Australia
Icon Cancer Foundation, South Brisbane, Queensland, Australia
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Royal Hobart Hospital; Hematology/Oncology, Hobart, Tasmania, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Austin Hospital Olivia Newton John Cancer Centre, Heidelberg, Victoria, Australia
Medizinische Universität Innsbruck; Universitätsklinik für Urologie, Innsbruck, , Austria
Ordensklinikum Linz Elisabethinen; Abteilung für Urologie und Andrologie, Linz, , Austria
Landeskrankenhaus Salzburg; Universitätsklinik für Urologie und Andrologie der PMU, Salzburg, , Austria
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Abt. für Onkologie, Wien, , Austria
Medizinische Universität Wien; Universitätsklinik für Urologie, Wien, , Austria
UZ Brussel, Brussel, , Belgium
Cliniques Universitaires St-Luc, Bruxelles, , Belgium
UZ Leuven Gasthuisberg, Leuven, , Belgium
CHU Sart-Tilman, Liège, , Belgium
Pronutrir - suporte nutricional e quimioterapia ltda., Fortaleza, CE, Brazil
Centro Integrado de Oncologia de Curitiba, Curitiba, PR, Brazil
Hospital Sao Lucas - PUCRS, Porto Alegre, RS, Brazil
Hospital de Cancer de Barretos, Barretos, SP, Brazil
Hospital Sírio-Libanês, Sao Paulo, SP, Brazil
Hospital Alemao Oswaldo Cruz, Sao Paulo, SP, Brazil
Complex Oncology Center (COC)-Plovidiv, Plovdiv, , Bulgaria
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD, Sofia, , Bulgaria
SHATOD - Sofia, Sofia, , Bulgaria
Tom Baker Cancer Centre-Calgary, Calgary, Alberta, Canada
Cross Cancer Institute ; Dept of Medical Oncology, Edmonton, Alberta, Canada
Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
Royal Victoria Hospital, Barrie, Ontario, Canada
The Ottawa Hospital Cancer Center; General Campus, Ottawa, Ontario, Canada
Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing City, , China
Clinica del Country, Bogota, , Colombia
Clinical Hospital Centre Zagreb, Zagreb, , Croatia
Fakultni nemocnice u sv. Anny v Brne, Brno, , Czechia
Fakultni nemocnice Kralovske Vinohrady, Praha, , Czechia
Fakultni Thomayerova Nemocnice; Onkologicke Oddeleni, Praha, , Czechia
Aalborg Universitetshospital; Onkologisk Afdeling, Aalborg, , Denmark
Aarhus Universitetshospital; Kræftafdelingen, Aarhus N, , Denmark
Herlev Hospital; Afdeling for Kræftbehandling, Herlev, , Denmark
Rigshospitalet; Onkologisk Klinik, København Ø, , Denmark
East Tallinn Central Hospital; Clinic of Internal Medicine, Tallinn, , Estonia
North Estonia Medical Centre Foundation; Oncology Center, Tallinn, , Estonia
Universitätsklinikum "Carl Gustav Carus"; Klinik und Poliklinik für Urologie, Dresden, , Germany
Universitätsklinikum Erlangen; Medizinische Klinik 5 - Hämatound Internist Onko, Erlangen, , Germany
Universitätsmedizin Göttingen Georg-August-Universität; Klinik für Urologie, Göttingen, , Germany
Krankenhaus Martha-Maria Halle-Dölau, Klinik für Urologie, Halle (Saale), , Germany
Medizinische Hochschule Hannover; Klinik für Urologie und Onkologische Urologie, Hannover, , Germany
Onkologische Schwerpunktpraxis, Heidelberg, , Germany
Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Urologie, Lübeck, , Germany
Kliniken Maria Hilf GmbH, Krankenhaus St. Franziskus, Mönchengladbach, , Germany
Klinikum rechts der Isar der TU München; Urologische Klinik und Poliklinik, München, , Germany
Universitätsklinikum Münster, Klinik für Urologie und Kinderurologie, Münster, , Germany
Universitätsklinikum Tübingen; Klinik für Urologie, Tübingen, , Germany
Universitätsklinikum Ulm; Klinik für Urologie, Ulm, , Germany
Alexandras General Hospital of Athens; Oncology Department, Athens, , Greece
IASO General Hospital of Athens, Athens, , Greece
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept., Kifisia, , Greece
Metropolitan Hospital; 2Nd Oncology Clinic, Piraeus, , Greece
Thermi Clinic; Oncology Clinic, Thermi Thessalonikis, , Greece
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, , Greece
Papageorgiou General Hospital; Medical Oncology, Thessaloniki, , Greece
Honvédelmi Minisztérium Állami Egészségügyi Központ; Onkológiai Osztály; Oncology department, Budapest, , Hungary
Semmelwies University of Medicine; Urology Dept., Budapest, , Hungary
Orszagos Onkologiai Intezet, Budapest, , Hungary
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, , Hungary
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház; Onkológiai Osztály, Szolnok, , Hungary
Max Super Speciality Hospital, New Delhi, Delhi, India
HealthCare Global Cancer Centre; Medical Oncology, Ahmedabad, Gujarat, India
Artemis Health Institute, Gurgaon, Haryana, India
TATA Medical Centre; Medical Oncology, Kolkata, WEST Bengal, India
Cork University Hospital, Cork, , Ireland
Adelaide & Meath Hospital, Dublin, Incorporating the National Children's Hospital; Oncology Day Unit, Dublin, , Ireland
Policlinico Ospedaliero Ss Annunziata; U.O. Di Clinica Oncologica, Chieti, Abruzzo, Italy
Azienda Ospedaliera Universitaria Federico II, Napoli, Campania, Italy
ISTITUTO NAZIONALE TUMORI IRCCS FONDAZIONE G. PASCALE; Dipartimento Uro-Ginecologico, Napoli, Campania, Italy
AZ.Osp S. Orsola ? Malpighi-Reparto di Oncologia Medica, Bologna, Emilia-Romagna, Italy
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna, Italy
A.O. Universitaria Policlinico Di Modena; Oncologia, Modena, Emilia-Romagna, Italy
Arcispedale Santa Maria Nuova; Oncologia, Reggio Emilia, Emilia-Romagna, Italy
A.O. Universitaria S. Maria Della Misericordia Di Udine; Oncologia, Udine, Friuli-Venezia Giulia, Italy
Policlinico Universitario Campus Biomedico Di Roma; U.O.Oncologia Medica, Roma, Lazio, Italy
Azienda Ospedaliera San Camillo Forlanini; Oncologia Medica, Roma, Lazio, Italy
Policlinico Universitario "Agostino Gemelli"; U.O.C. Oncologia Medica, Roma, Lazio, Italy
IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A, Genova, Liguria, Italy
Asst Papa Giovanni XXIII; Oncologia Medica, Bergamo, Lombardia, Italy
ASST DI CREMONA; Dip. Medicina - S.C. Oncologia, Cremona, Lombardia, Italy
Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 2, Milano, Lombardia, Italy
Istituto Europeo Di Oncologia, Milano, Lombardia, Italy
A.O. UNIVERSITARIA S. LUIGI GONZAGA; Oncologia Medica, Orbassano, Piemonte, Italy
Irccs Ist. Tumori Giovanni Paolo Ii; Dipartimento Oncologia Medica, Bari, Puglia, Italy
IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia, San Giovanni Rotondo, Puglia, Italy
A.O.U. Cagliari-P.O. Monserrato;U.O. Oncologia, Cagliari, Sardegna, Italy
Ospedale Cannizzaro, Oncologia, Catania, Sicilia, Italy
Azienda USL8 Arezzo-Presidio Ospedaliero 1 San Donato;U.O.C. Oncologia, Arezzo, Toscana, Italy
Azlenda Ospendaliero-Universitaria Pisana; C.O. Oncologia 2, Pisa, Toscana, Italy
Azienda Ospedaliera S. Maria - Terni; Oncologia, Terni, Umbria, Italy
IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Prima, Padova, Veneto, Italy
Azienda Ospedaliera di Verona-Policlinico G.B. Rossi; Oncologia Medica, Verona, Veneto, Italy
Hotel Dieu de France; Oncology, Beirut, , Lebanon
Hospital of Lithuanian University of Health Sciences Kaunas Clinics - Endocrinology clinic, Kaunas, , Lithuania
National Cancer Institute, Vilnius, , Lithuania
NKI/AvL, Amsterdam, , Netherlands
VU MEDISCH CENTRUM; Dept. of Medical Oncology, Amsterdam, , Netherlands
Academ Ziekenhuis Groningen; Medical Oncology, Groningen, , Netherlands
Maastricht University Medical Centre; Medical Oncology, Maastricht, , Netherlands
St. Antonius locatie Leidsche Rijn, Utrecht, , Netherlands
NZOZ Onko-Dent G. L. Slomian, Spolka Jawna, ?ory, , Poland
Centrum Onkologii Ziemi LUBELSKIEJ im. Sw Jana z Dukli, I oddz. Chemioterapii, Lublin, , Poland
Szpital Kliniczny Przemienienia Pa?skiego Uniwersytetu Medycznego im. Karola Marcinkowskiego, Poznan, , Poland
Szpital Grochowski im. dr med. Rafa?a Masztaka Sp. z o.o., Warszawa, , Poland
Hospital de Braga; Servico de Oncologia Medica X, Braga, , Portugal
HUC; Servico de Urologia e Transplantacao Renal, Coimbra, , Portugal
Hospital de Santa Maria; Servico de Oncologia Medica, Lisboa, , Portugal
IPO do Porto; Servico de Oncologia Medica, Porto, , Portugal
Oncopremium Team Srl, Baia Mare, , Romania
Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj-Napoca; Spital de zi-Parter, Cluj-Napoca, , Romania
Centrul de Oncologie Sfantul Nectarie, Craiova, , Romania
Centrul de Radioterapie AMETHYST, Floresti, , Romania
Oncomed SRL; Oncologie, Timisoara, , Romania
Blokhin Cancer Research Center; Urological Dept, Moscow, Moskovskaja Oblast, Russian Federation
P.A. Herzen Oncological Inst. ; Oncology, Moscow, Moskovskaja Oblast, Russian Federation
King Faisal Specialist Hospital & Research Centre; Oncology, Riyadh, , Saudi Arabia
Narodny onkologicky ustav, Bratislava, , Slovakia
Hospital Univ. Central de Asturias; Servicio de Oncologia, Oviedo, Asturias, Spain
Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia, Badalona, Barcelona, Spain
Complejo Hospitalario de Althaia; Servicio de Oncologia, Manresa, Barcelona, Spain
Corporacio Sanitaria Parc Tauli; Servicio de Oncologia, Sabadell, Barcelona, Spain
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona, Spain
Hospital Universitario Reina Sofia; Servicio de Oncologia, Córdoba, Cordoba, Spain
Hospital Universitario Son Espases; Servicio de Oncologia, Palma De Mallorca, Islas Baleares, Spain
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña, Spain
Hospital Universitario de Canarias;servicio de Oncologia, La Laguna, Tenerife, Spain
Hospital de Basurto; Servicio de Oncologia, Bilbao, Vizcaya, Spain
Hospital del Mar Barcelona, Barcelona, , Spain
Hospital Clínic i Provincial; Servicio de Oncología, Barcelona, , Spain
Hospital de la Santa Creu i Sant Pau; Servicio de Oncologia, Barcelona, , Spain
Hospital Duran i Reynals; Oncologia, Barcelona, , Spain
Hospital San Pedro De Alcantara; Servicio de Oncologia, Caceres, , Spain
Hospital Universitari de Girona Dr. Josep Trueta; Servicio de Oncologia, Girona, , Spain
Hospital General Universitario de Guadalajara; Servicio de Oncologia, Guadalajara, , Spain
Hospital Lucus Augusti; Servicio de Oncologia, Lugo, , Spain
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, , Spain
Hospital Clinico San Carlos; Servicio de Oncologia, Madrid, , Spain
Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, , Spain
Hospital Universitario La Paz; Servicio de Oncologia, Madrid, , Spain
HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia, Madrid, , Spain
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, , Spain
Hospital General Universitario J.M Morales Meseguer; Servicio de Oncologia, Murcia, , Spain
Hospital de Navarra; Servicio de Oncologia, Navarra, , Spain
Complejo Hospitalario de Orense; Servicio de Oncologia, Orense, , Spain
Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, , Spain
Complejo Hospitalario de Toledo- H. Virgen de la Salud; Servicio de Oncologia, Toledo, , Spain
Hospital Clínico Universitario de Valencia; Servicio de Oncología, Valencia, , Spain
Hospital General Universitario de Valencia; Servicio de oncologia, Valencia, , Spain
Hospital La Fe, Valencia, , Spain
Universitaetsspital Basel; Onkologie, Basel, , Switzerland
Ospedale Regionale di Bellinzona Medizin Onkologie, Bellinzona, , Switzerland
Inselspital Bern; Universitätsklinik für Medizinische Onkologie, Klinische Forschungseinheit, Bern, , Switzerland
Kantonsspital Graubünden Medizin Onkologie; Onkologie und Hämatologie, Chur, , Switzerland
Hôpitaux Universit. de Genève Médecine Oncologie; Oncologie, Geneve, , Switzerland
Luzerner Kantonsspital; Medizinische Onkologie, Luzern, , Switzerland
Kantonsspital Winterthur; Medizinische Onkologie, Winterthur, , Switzerland
National Cheng Kung Uni Hospital; Dept of Hematology and Oncology, Tainan, , Taiwan
Chang Gung Medical Foundation-Linkou, Urinary Oncology, Taoyuan, , Taiwan
Velindre Cancer Centre, Cardiff, , United Kingdom
Raigmore Hospital; Dept of Radiotherapy & Oncology, Inverness, , United Kingdom
Leicester Royal Infirmary NHS Trust, Leicester, , United Kingdom
Barts and the London NHS Trust., London, , United Kingdom
Royal Marsden NHS Foundation Trust, Sutton, , United Kingdom
Contact Details
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR
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