Spots Global Cancer Trial Database for A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
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Trial Identification
Brief Title: A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
Official Title: A Phase 3 Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Subjects With Advanced Urothelial Cancer and Selected FGFR Gene Aberrations
Study ID: NCT03390504
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-\[L\]1) agent (cohort 1) or 1 prior treatment not containing an anti-PD-(L) 1 agent (cohort 2).
Detailed Description: A study of erdafitinib versus standard of care, consisting of chemotherapy (docetaxel or vinflunine) or anti-PD-(L) 1 agent pembrolizumab, in participants with advanced urothelial cancer and selected FGFR aberrations who have progressed on or after 1 or 2 prior treatments, at least 1 of which includes an anti-PD-(L) 1 agent (cohort 1) or 1 prior treatment not containing an anti-PD-(L) 1 agent (cohort 2). It will consist of screening, treatment phase (from randomization until disease progression, intolerable toxicity, withdrawal of consent or decision by investigator to discontinue treatment, post-treatment follow-up (from end-of-treatment to participants death, withdraws consent, lost to follow-up study completion for the respective cohort, whichever comes first). The study will have long term extension (LTE) period after clinical cutoff date is achieved for final analysis of each cohort and participants eligible in the opinion of the investigator, will continue to benefit from the study intervention. Efficacy, pharmacokinetics, biomarkers, patient reported outcomes, medical resource utilization and safety will be assessed.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Alaska Urological Institute dba Alaska Clinical Research Center, Anchorage, Alaska, United States
University of Calif Davis Medical Center, Sacramento, California, United States
St. Helena Hospital - Martin-O'Neil Cancer Center, Saint Helena, California, United States
MedStar Georgetown University Hospital, Washington, District of Columbia, United States
University of Miami Sylvester Cancer Center, Miami, Florida, United States
Mid Florida Hematology Oncology, Orange, Florida, United States
Piedmont Cancer Institute, Atlanta, Georgia, United States
Rush University, Chicago, Illinois, United States
Edward Hines Jr V A Hospital, Hines, Illinois, United States
Norton Cancer Institute, Louisville, Kentucky, United States
Maryland Oncology Hematology, PA, Lanham, Maryland, United States
University of Michigan Health System, Ann Arbor, Michigan, United States
VA Sierra Nevada Health Care System, Reno, Nevada, United States
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
Montefiore Medical Center, Bronx, New York, United States
Weill Cornell Medical College, New York, New York, United States
Levine Cancer Institute, Carolinas HealthCare System, Charlotte, North Carolina, United States
W. G. 'Bill' Hefner VA Medical Center, Salisbury, North Carolina, United States
Oncology Hematology Care, Cincinnati, Ohio, United States
The Center for Cancer and Blood Disorders, Fort Worth, Texas, United States
Texas Oncology-Memorial City, Houston, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
Texas Oncology Tyler, Tyler, Texas, United States
INOVA Dwiight &Martha Schar Cancer Institute, Fairfax, Virginia, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
VA Puget Sound Healthcare System, Seattle, Washington, United States
Sociedade Beneficente de Senhoras - Hospital Sírio Libanês, Buenos Aires, , Argentina
Centro Oncológico Korben, Buenos Aires, , Argentina
CEMIC Saavedra, Ciudad Autonoma de Buenos Aires, , Argentina
Cemaic - Centro Privado de Especialidades Medicas Ambulatorias e Investigacion Clinica, Cordoba, , Argentina
Centro Urologico Profesor Bengio, Cordoba, , Argentina
Hospital Privado de Comunidad, Mar Del Plata, , Argentina
Centro de Investigacion Pergamino SA, Pergamino, , Argentina
Clínica Viedma, Viedma, , Argentina
Chris O'Brien Lifehouse, Camperdown, , Australia
Peninsula & South Eastern Haematology and Oncology Group, Frankston, , Australia
St George Hospital, Kogarah, , Australia
Peter MacCallum Cancer Centre, Melbourne, , Australia
Frankston Hospital, Melbourne, , Australia
Fiona Stanley Hospital, Murdoch, , Australia
LKH-Univ. Klinikum Graz, Graz, , Austria
Ordensklinikum Linz GmbH Elisabethinen, Linz, , Austria
LKH - Universitätsklinikum der PMU Salzburg, Salzburg, , Austria
Krankenhaus der Barmherzigen Brüder, Vienna, , Austria
Medical University Vienna MUV, Vienna, , Austria
OLV Ziekenhuis Aalst, Aalst, , Belgium
ZNA Middelheim, Antwerpen, , Belgium
Cliniques Universitaires Saint Luc, Bruxelles, , Belgium
Clinique Notre Dame de Grâce, Charleroi, , Belgium
AZ Maria Middelares, Gent, , Belgium
UZ Gent, Gent, , Belgium
CHC MontLegia, Liege, , Belgium
Sint-Augustinus AZ, Wilrijk, , Belgium
CHU UCL Namur - Site Godinne, Yvoir, , Belgium
Fundacao Pio XII, Barretos, , Brazil
Universidade Federal De Minas Gerais - Hospital das Clínicas, Belo Horizonte, , Brazil
Nucleo de Ensino e Pesquisa do Instituto Mario Penna, Belo Horizonte, , Brazil
Instituto de Oncologia do Paraná, Curitiba, , Brazil
Liga Paranaense de Combate ao Cancer, Curitiba, , Brazil
Associacao de Combate ao Cancer em Goias - Hospital de Cancer Araujo Jorge, Goiania, , Brazil
Clínica de Neoplasias Litoral Ltda., Itajai, , Brazil
Fundacao Doutor Amaral Carvalho, Jau, , Brazil
Liga Norte Riograndense Contra O Cancer, Natal, , Brazil
Hospital das Clinicas de Porto Alegre, Porto Alegre, , Brazil
Hospital Nossa Senhora da Conceicao S A, Porto Alegre, , Brazil
Ministerio da Saude - Instituto Nacional do Cancer, Rio De Janeiro, , Brazil
Oncoclinicas Rio de Janeiro S A, Rio de Janeiro, , Brazil
Hospital Sao Rafael, Salvador, , Brazil
CEPHO - Centro de Estudos e Pesquisa de Hematologia e Oncologia, Santo Andre, , Brazil
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto - Hospital de Base, Sao Jose do Rio Preto, , Brazil
Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, , Brazil
Instituto Brasileiro de Controle do Cancer - Sao Camilo Oncologia, Sao Paulo, , Brazil
Instituto de Oncologia de Sorocaba Onco Clinicas Especializadas, Sorocaba, , Brazil
Sociedade Beneficente de Senhoras - Hospital Sírio Libanês, São Paulo, , Brazil
Instituto D Or de Pesquisa e Ensino (IDOR), São Paulo, , Brazil
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo, , Brazil
UMHAT 'Dr. Georgi Stranski', EAD, Pleven, , Bulgaria
Complex Oncology Center - Plovdiv EOOD, Plovdiv, , Bulgaria
Multiprofile Hospital for Active Treatment 'Tokuda Hospital Sofia', Sofia, , Bulgaria
UMHAT Sofia Med, Sofia, , Bulgaria
Multiprofile Hospital for Active Treatment 'Sveta Marina' EAD, Varna, , Bulgaria
BC Cancer Agency - Southern Interior, Kelowna, British Columbia, Canada
Vancouver Cancer Centre, Vancouver, British Columbia, Canada
Cancercare Manitoba, Winnipeg, Manitoba, Canada
Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario, Canada
Princess Margaret Hospital- UHN, Toronto, Ontario, Canada
Saskatchewan Cancer Agency (SCA) - Allan Blair Cancer Centre, Regina, Saskatchewan, Canada
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, , China
Peking University First Hospital, Beijing, , China
Beijing Friendship Hospital, Beijing, , China
Peking University Third Hospital, Beijing, , China
Beijing Hospital, Beijing, , China
Peking Union Medical College Hospital, Beijing, , China
The First Bethune Hospital of Jilin University, Changchun, , China
Sichuan Provincial Peoples Hospital, Chengdu, , China
Sichuan University Huaxi Hospital, Chengdu, , China
Chongqing University Cancer Hospital, ChongQing, , China
Sun Yat-Sen University Cancer Center, Guangzhou, , China
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, , China
Guangzhou First Municipal People's Hospital, Guangzhou, , China
Zhejiang Provincial People's Hospital, Hangzhou, , China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, , China
The First Affliated Hospital Of Nanchang University, Nanchang, , China
Nanjing Drum Tower Hospital, Nanjing, , China
Jiangsu Cancer Hospital, Nanjing, , China
Renji Hospital, Shanghai Jiaotong University School of Medicine, ShangHai, , China
Huadong Hospital Affiliated to Fudan University, Shanghai, , China
Shengjing Hospital of China Medical University, Shenyang, , China
Shenzhen university General Hospital, Shenzhen, , China
First Affiliated Hospital of Wenzhou Medical College, Wenzhou, , China
The First Affiliated Hospital of Xian Jiaotong University, Xian, , China
Institut de Cancerologie de l Ouest ICO, Angers, , France
Hopital Jean Minjoz, Besancon Cedex, , France
Institut Bergonié, Bordeaux, , France
CHRU Brest - Hopital Morvan, Brest, , France
Centre Jean Perrin, Clermont Ferrand, , France
Centre Georges-François Leclerc, Dijon, , France
Hôpital Privé Le Bois, Lille, , France
Centre Oscar Lambret, Lille, , France
Groupe Hospitalier Bretagne Sud, Lorient, , France
Hopital de la Timone, Marseille, , France
Institut Regional du Cancer de Montpellier Val d'Aurelle, Montpellier, , France
Centre Antoine Lacassagne, Nice, , France
Institut de Cancérologie du Gard, Nîmes, , France
Hospital Saint-Louis, Paris Cedex 10, , France
Hopital Europeen Georges-Pompidou, Paris, , France
Hospices Civils de Lyon HCL, Pierre-Bénite, , France
CHU De Poitiers, Poitiers Cedex, , France
Centre Eugene Marquis, Rennes Cedex, , France
Centre de radiothérapie et d'Oncologie médicale de l'Essonne, Ris Orangis, , France
Institut de Cancérologie de Loire, Saint-Priest-en-Jarez, , France
Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre, Strasbourg Cedex, , France
Institut Claudius Regaud, Toulouse, , France
Centre Les Dentellieres, Valenciennes, , France
Institut Gustave Roussy, Villejuif, , France
Vivantes Klinikum Am Urban, Berlin, , Germany
Stadtisches Klinikum Braunschweig gGmbH-Klinik fur Urologie und Uroonkologie, Braunschweig, , Germany
Universitatsklinikum Carl Gustav Carcus Dresden, Dresden, , Germany
Universitaetsklinikum Duesseldorf, Duesseldorf, , Germany
Friedrich-Alexander Universitaet Urologische Universitaetskl, Erlangen, , Germany
Universitatsklinikum Frankfurt, Frankfurt, , Germany
Universitatsklinikum Freiburg, Freiburg, , Germany
Universitätsmedizin Greifswald, Greifswald, , Germany
Universitatsmedizin Gottingen, Göttingen, , Germany
Asklepios Klinik Altona, Hamburg, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Universitatsklinikum Schleswig Holstein Campus Lubeck, Lubeck, , Germany
Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, , Germany
Universitaetsklinikum Muenster, Muenster, , Germany
Studienpraxis Urologie Drs. Feyerabend, Nuertingen, , Germany
Caritas-Krankenhaus St. Josef, Regensburg, , Germany
Universitaetsmedizin Rostock, Rostock, , Germany
MVZ-Onkologie Velbert GbR, Velbert, , Germany
Kliniken Nordoberpfalz AG/Klinikum Weiden, Weiden, , Germany
Errikos Dunant Hospital Center, Athens, , Greece
Athens Medical Center, Athens, , Greece
Metropolitan General A.E., Athens, , Greece
University of Athens Medical School - Regional General Hospi, Athina, , Greece
University Hospital Of Larissa, Larisa, , Greece
University General Hospital of Rio Patras, Patras, , Greece
Interbalkan European Medical Center, Thessaloniki, , Greece
Euromedica General Clinic, Thessaloniki, , Greece
'Papageorgiou' General Hospital of Thessaloniki, Thessaloniki, , Greece
Semmelweis Egyetem, Budapest, , Hungary
Országos Onkológiai Intézet, Urogenitális Tumorok és Klinikai Farmakológiai Osztály, Budapest, , Hungary
Budapesti Uzsoki Utcai Korhaz, Budapest, , Hungary
Szabolcs-Szatmar-Bereg Megyei Korhazak es Egyetemi Oktatokorhaz, Nyíregyháza, , Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont, Pécs, , Hungary
Rambam Health Care Campus, Haifa, , Israel
Hadassah Medical Center, Jerusalem, , Israel
Meir Medical Center, Kfar Saba, , Israel
Rabin Medical Center, Beilinson Hospital, Petach Tikvah, , Israel
The Chaim Sheba Medical Center, Tel Hashomer, , Israel
Sourasky Medical Center, Tel-Aviv, , Israel
Assaf Harofeh Medical Center, Tzrifin, , Israel
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria, Alessandria, , Italy
Ospedale S. Donato - Asl 8 Arezzo, Arezzo, , Italy
CRO IRCCS Istituto Nazionale Tumori, Aviano, , Italy
Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, , Italy
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Presidio Spedali Civili, Brescia, , Italy
Istituti Ospitalieri di Cremona, AO di Cremona, Cremona, , Italy
Oncologia Medica, Firenze, , Italy
SPDC Villa Scassi, Genova, , Italy
UOC Oncologia Ospedale Provinciale di Macerata, Macerata, , Italy
IRST Meldola Forli, Meldola, , Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, , Italy
European Institute of Oncology, Milano, , Italy
IRCCS Ospedale San Raffaele, Milan, , Italy
AOU Policlinico di Modena, Modena, , Italy
IRCCS-Fondazione Pascale, Napoli, , Italy
Ospedale Maggiore della Carita, Novara, , Italy
Aou San Luigi Gonzaga, Orbassano, , Italy
Istituto Oncologico Veneto Iov Irccs Padova, Padova, , Italy
AOU di Parma, Parma, , Italy
IRCCS Policlinico San Matteo, Pavia, , Italy
Ist. Clinici Scientifici Maugeri - Unità Operativa di Oncolo, Pavia, , Italy
Azienda Ospedaliero Universitaria Pisana, Pisa, , Italy
Usl 7 Siena - Ospedale Alta Valdelsa ASL TOSCANA SUD-EST, Poggibonsi (SI), , Italy
Fondazione Policlinico Universitario A Gemelli IRCCS, Roma, , Italy
Azienda Ospedaliera Universitaria Senese Policlinico Santa Maria alle Scotte, Siena, , Italy
Oncologia Medica-Città Della Salute E Della Scienza Di Torino, Torino, , Italy
Azienda Ospedaliero - Universitaria Ospedali Riuniti, Torrette Di Ancona, , Italy
Chiba Cancer Center, Chiba, , Japan
Hirosaki University Hospital, Hirosaki, , Japan
National Cancer Center Hospital East, Kashiwa, , Japan
Kagawa University Hospital, Kita-Gun, , Japan
Kobe City Medical Center General Hospital, Kobe, , Japan
Dokkyo Medical University Saitama Medical Center, Koshigaya, , Japan
National Hospital Organizaiton Shikoku Cancer Center, Matsuyama, , Japan
University of Miyazaki Hospital, Miyazaki, , Japan
Nagano Municipal Hospital, Nagano, , Japan
Aichi Cancer Center Hospital, Nagoya Shi, , Japan
Kindai University Hospital, Osaka-Sayama, , Japan
Osaka International Cancer Institute, Osaka, , Japan
Osaka City University Hospital, Osaka, , Japan
Gunma Prefectural Cancer Center, Ota, , Japan
Kitasato University Hospital, Sagamihara, , Japan
Toho University Sakura Medical Center, Sakura, , Japan
National Hospital Organization Hokkaido Cancer Center, Sapporo, , Japan
Tokyo Women's Medical University Hospital, Shinjuku-ku, , Japan
Toranomon Hospital, Tokyo, , Japan
The Cancer Institute Hospital of JFCR, Tokyo, , Japan
University of Tsukuba Hospital, Tsukuba, , Japan
Yamaguchi University Hospital, Ube, , Japan
Yokohama City University Medical Center, Yokohama, , Japan
Pusan National University Hospital, Busan, , Korea, Republic of
Chungnam National University Hospital, Daejeon, , Korea, Republic of
National Cancer Center, Goyangsi, , Korea, Republic of
Chonnam National University Hospital, Gwangju, , Korea, Republic of
Seoul National University Bundang Hospital, Gyeonggi-do, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Kangbuk Samsung Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Yonsei University Wonju Severance Christian Hospital, Wonju-si, , Korea, Republic of
Medicos Especialistas en Cancer, S.C., Aguascalientes, , Mexico
Centro Estatal de Cancerología de Chihuahua, Chihuahua, , Mexico
Oncologia Integral Satelite, Naucalpan, , Mexico
NKI-AVL, Amsterdam, Amsterdam, , Netherlands
Haga ziekenhuis, Den Haag, , Netherlands
St. Antonius Ziekenhuis Nieuwegein, Nieuwegein, , Netherlands
Centrum Onkologii im. Prof. F. Lukaszczyka w Bydgoszczy, Bydgoszcz, , Poland
Centralny Szpital Kliniczny MSWiA w Warszawie, Warszawa, , Poland
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy, Warszawa, , Poland
Uniwersytecki Szpital Kliniczny we Wrocławiu, Wroclaw, , Poland
Hospital Lusíadas, Lisboa, , Portugal
H. Santa Maria - Centro Hospitalar de Lisboa Norte, Lisboa, , Portugal
Chlc - Hosp. Sto Antonio Dos Capuchos, Lisboa, , Portugal
Champalimaud Foundation Champalimaud Centre, Lisbon, , Portugal
Instituto Portugues de Oncologia, Porto, , Portugal
Altai Regional Oncology Dispensary, Barnaul, , Russian Federation
Chelyabinsk Regional Clinical Center Of Oncology And Nuclear Medicine, Chelyabinsk, , Russian Federation
Irkutsk Regional Oncology Dispensary, Irkutsk, , Russian Federation
Ivanovo Regional Oncology Dispensary, Ivanovo, , Russian Federation
Kostroma regional oncology dispensary, Kostroma, , Russian Federation
Leningrad Regional Oncology Dispensary, Kuzmolovsky, , Russian Federation
City Clinical Hospital n.a. D.D.Pletnev, Moscow, , Russian Federation
FSBSI 'N. N. Blokhin Russian Cancer Research Center', Moscow, , Russian Federation
Russian Scientific Center of Roentgenoradiology, Moscow, , Russian Federation
I.M. Sechenov First Moscow State Medical University, Moscow, , Russian Federation
Hertzen Oncology Research Institute, Moscow, , Russian Federation
City Clinical Hospital #1, Nalchik, , Russian Federation
Privolzhsky District Medical Center under the Federal Medico-Biological Agency, Nizhni Novgorod, , Russian Federation
Clinical Oncology Dispensary, Omsk, , Russian Federation
GBUZ of Stavropol region Pyatigorsk Oncological Dispensary, Pyatigorsk, , Russian Federation
Private Medical Institution Euromedservice, Saint Petersburg, , Russian Federation
Pavlov First Saint Petersburg State Medical University, Saint Petersburg, , Russian Federation
LLC 'Strategic Medical Systems', Saint-Petersburg, , Russian Federation
Clinical hopital n/a Petra velikogo, Saint-Petersburg, , Russian Federation
FGBOU Vo Mordovian National Research State University N. A. N.P. Ogareva, Saransk, , Russian Federation
Saratov State Medical University, Saratov, , Russian Federation
LLC Uromed, Smolensk, , Russian Federation
GBUZ Oncology Centre #2 of Healthcare Department of Krasno, Sochi, , Russian Federation
Russian Scientific Center of Radiology and Surgical Technologies, St. Petersburg, , Russian Federation
Saint-Petersburg Clinical Scientific And Practical Center For Special Types Of Medical Care, St.Petersburg, , Russian Federation
Multifunctional clinical medical center 'Medical city', Tyumen, , Russian Federation
Bashkiria State Medical University, Ufa, , Russian Federation
Vologda Regional Oncological Dispensary, Vologda, , Russian Federation
Hosp. Univ. Infanta Cristina, Badajoz, , Spain
Institut Català D'Oncologia-Hospital Universitari Germans Trias I Pujol, Badalona, , Spain
Hosp. Clinic de Barcelona, Barcelona, , Spain
Hosp. de La Santa Creu I Sant Pau, Barcelona, , Spain
Hosp. San Pedro de Alcantara, Cáceres, , Spain
Hosp. Reina Sofia, Córdoba, , Spain
Hosp. Univ. Virgen de Las Nieves, Granada, , Spain
Complejo Hospitalario de Jaen, Jaén, , Spain
Hosp. Univ. Insular de Gran Canaria, Las Palmas de Gran Canaria, , Spain
Hosp. Univ. Lucus Augusti, Lugo, , Spain
Hosp. Univ. 12 de Octubre, Madrid, , Spain
Hosp. Univ. La Paz, Madrid, , Spain
Hosp. Univ. Pta. de Hierro Majadahonda, Majadahonda, , Spain
ALTHAIA, Xarxa Assistencial Universitària de Manresa, Manresa, , Spain
Hosp. de Navarra, Pamplona, , Spain
Hosp. Virgen Macarena, Sevilla, , Spain
Hosp. Virgen Del Rocio, Sevilla, , Spain
Hosp. Gral. Univ. Valencia, Valencia, , Spain
Hosp. Univ. I Politecni La Fe, Valencia, , Spain
Hosp. Univ. Miguel Servet, Zaragoza, , Spain
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, , Taiwan
Chang Gung Medical Foundation, Niao-Sung Hsiang, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
Chi Mei Medical Center Yong Kang, Tainan, , Taiwan
National Taiwan University Hospital, Taipei City, , Taiwan
Mackay Memorial Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Koo Foundation Sun Yat-Sen Cancer Center, Taipei, , Taiwan
Chang-Gung Memorial Hospital, LinKou Branch, Taoyuan, , Taiwan
Baskent University Adana Practice and Research Center Kisla Health Campus, Adana, , Turkey
Hacettepe University Medical Faculty, Ankara, , Turkey
Bezmialem University Medical Faculty, Istanbul, , Turkey
Istanbul University Cerrahpasa Medical Faculty, Istanbul, , Turkey
Bakirkoy Training and Research Hospital, Istanbul, , Turkey
Medipol Mega University Hospital, Istanbul, , Turkey
T.C. Saglik Bakanlıgi Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi, Istanbul, , Turkey
Pendik Training and Research Hospital, Istanbul, , Turkey
Ege University, Izmir, , Turkey
Dokuz Eylul Universitesi Tip Fakultesi, Izmir, , Turkey
Kocaeli University Medical Faculty, Kocaeli, , Turkey
Inonu Universitesi Turgut Ozal Tip Merkezi, Ic Hastaliklari, Malatya, , Turkey
MI Dnipropetrovsk Region Clinical Hospital n a I.I.Mechnikov, Dnipropetrovsk, , Ukraine
Municipal Institution 'Clinical Oncology Dispensary' Under Dnipropetrovsk Regional Council, Dnipro, , Ukraine
Dnipropetrovsk State Medical Academy, Dnipropetrovsk City Multifield Clinical Hospital # 4, Dnipro, , Ukraine
Ivano-Frankivsk Regional Clinical Hospital, Ivano-Frankivsk, , Ukraine
Regional Medical Clinical Center for Urology and Nephrology named after V.I. Shapoval, Kharkiv, , Ukraine
Municipal non-profit enterprise 'Regional Center of Oncology', Kharkiv, , Ukraine
National Cancer Institute, Kyiv, , Ukraine
State Institution Institute of Urology NAMS of Ukraine based on Kyiv City Clinical Oncology Center, Kyiv, , Ukraine
Communal Noncommercial Enterprise of Lviv Regional Council 'Lviv Regional Clinical Hospital', Lviv, , Ukraine
Transkarpathian Regional University Oncology Clinic, Uzhgorod, , Ukraine
Podilskiy Regional Center of Oncology, Vinnitsa, , Ukraine
Zaokod, Zaporizhzhia, , Ukraine
Zaporizhzhia medical Academy of postgraduate education, Zaporizhzhia Regoinal Clinical Hospital, Zaporizhzhia, , Ukraine
University Hospitals Bristol - Bristol Haematology & Oncolog, Bristol, , United Kingdom
St Bartholomew's Hospital, London, , United Kingdom
Sarah Cannon Research Institute, London, , United Kingdom
Charing Cross Hospital, London, , United Kingdom
The Christie NHS Foundation Trust Christie Hospital, Manchester, , United Kingdom
Derriford Hospital-Department of Medical Oncology, Plymouth, , United Kingdom
University of Sheffield, Sheffield, , United Kingdom
Southampton General Hospital, Southampton, , United Kingdom
Royal Marsden Hospital, Sutton, , United Kingdom
Contact Details
Name: Janssen Research & Development, LLC Clinical Trial
Affiliation: Janssen Research & Development, LLC
Role: STUDY_DIRECTOR
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