Spots Global Cancer Trial Database for Prevalence of PD-L1 Expression in Patients With Advanced Urothelial Carcinoma
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Trial Identification
Brief Title: Prevalence of PD-L1 Expression in Patients With Advanced Urothelial Carcinoma
Official Title: A Prospective, Non-Interventional Study to Assess the Prevalence of PD-L1 Expression in the First-Line Setting of Locally Advanced/Unresectable or Metastatic Urothelial Carcinoma
Study ID: NCT03788746
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to assess the prevalence of pre-treatment tumor tissue PD-L1 expression in patients diagnosed with advanced urothelial carcinoma.
Detailed Description: Advanced urothelial carcinoma (UC) (locally advanced/unresectable or metastatic UC) is a fatal disease with 5-year survival rate of 5%. The most frequently studied diagnostic for advanced UC is the programmed death-ligand 1 (PD-L1) protein expression in tumor tissue. A better understanding of PD-L1 expression in a "real world" setting could help understand its clinical utility in the management and decision making in advanced UC and clinical trial design
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Little Rock, Arkansas, United States
Research Site, Glendale, California, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Monterey, California, United States
Research Site, Santa Rosa, California, United States
Research Site, Denver, Colorado, United States
Research Site, Englewood, Colorado, United States
Research Site, Hartford, Connecticut, United States
Research Site, Stamford, Connecticut, United States
Research Site, Boca Raton, Florida, United States
Research Site, Hialeah, Florida, United States
Research Site, Jacksonville, Florida, United States
Research Site, Augusta, Georgia, United States
Research Site, Roswell, Georgia, United States
Research Site, Geneva, Illinois, United States
Research Site, Harvey, Illinois, United States
Research Site, Lake Barrington, Illinois, United States
Research Site, Naperville, Illinois, United States
Research Site, Greenwood, Indiana, United States
Research Site, Lafayette, Indiana, United States
Research Site, Muncie, Indiana, United States
Research Site, Cedar Rapids, Iowa, United States
Research Site, Waterloo, Iowa, United States
Research Site, Kansas City, Kansas, United States
Research Site, Wichita, Kansas, United States
Research Site, Baton Rouge, Louisiana, United States
Research Site, Shreveport, Louisiana, United States
Research Site, Brewer, Maine, United States
Research Site, Lewiston, Maine, United States
Research Site, Grand Rapids, Michigan, United States
Research Site, Duluth, Minnesota, United States
Research Site, Saint Cloud, Minnesota, United States
Research Site, Bridgeton, Missouri, United States
Research Site, Las Vegas, Nevada, United States
Research Site, Berkeley Heights, New Jersey, United States
Research Site, East Brunswick, New Jersey, United States
Research Site, Englewood, New Jersey, United States
Research Site, Freehold, New Jersey, United States
Research Site, Little Silver, New Jersey, United States
Research Site, Mount Laurel, New Jersey, United States
Research Site, Albany, New York, United States
Research Site, Johnson City, New York, United States
Research Site, Port Jefferson Station, New York, United States
Research Site, Greenville, North Carolina, United States
Research Site, Cincinnati, Ohio, United States
Research Site, Kettering, Ohio, United States
Research Site, Myrtle Beach, South Carolina, United States
Research Site, Knoxville, Tennessee, United States
Research Site, Nashville, Tennessee, United States
Research Site, Temple, Texas, United States
Research Site, The Woodlands, Texas, United States
Research Site, Virginia Beach, Virginia, United States
Research Site, Olympia, Washington, United States
Research Site, Renton, Washington, United States
Research Site, Seattle, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Wenatchee, Washington, United States
Contact Details
Name: Petros Grivas, MD
Affiliation: University of Washington
Role: STUDY_CHAIR
Name: Joshua Meeks
Affiliation: Northwestern University
Role: STUDY_CHAIR
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