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Spots Global Cancer Trial Database for An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer

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Trial Identification

Brief Title: An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer

Official Title: A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab Versus Placebo in Subjects With High Risk Invasive Urothelial Carcinoma (CheckMate 274: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 274)

Study ID: NCT02632409

Interventions

Nivolumab
Placebo

Study Description

Brief Summary: The purpose of this study is to determine the effectiveness and safety of Nivolumab compared to placebo in participants who have undergone radical surgery for invasive urothelial cancer.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Alaska Urological Institute dba Alaska Clinical Research Center, Anchorage, Alaska, United States

Local Institution - 0179, Tucson, Arizona, United States

Local Institution - 0061, Clovis, California, United States

Local Institution - 0172, Sacramento, California, United States

Local Institution - 0005, San Francisco, California, United States

Local Institution - 0178, Lakewood, Colorado, United States

Local Institution - 0167, Gainesville, Florida, United States

Local Institution - 0030, Miami Beach, Florida, United States

Local Institution - 0008, Tampa, Florida, United States

Local Institution - 0168, Maywood, Illinois, United States

Local Institution - 0094, Fort Wayne, Indiana, United States

Local Institution - 0171, New Orleans, Louisiana, United States

Local Institution - 0173, Grand Rapids, Michigan, United States

Local Institution - 0051, Burnsville, Minnesota, United States

Local Institution - 0004, Rochester, Minnesota, United States

Local Institution - 0003, Omaha, Nebraska, United States

Local Institution - 0177, Las Vegas, Nevada, United States

Local Institution - 0176, Albany, New York, United States

Local Institution - 0157, Buffalo, New York, United States

Local Institution - 0007, Mineola, New York, United States

Local Institution - 0001, New York, New York, United States

Local Institution - 0006, New York, New York, United States

Local Institution - 0166, Chapel Hill, North Carolina, United States

Local Institution, Durham, North Carolina, United States

Local Institution - 0044, Portland, Oregon, United States

Local Institution - 0010, Portland, Oregon, United States

Local Institution - 0180, Tigard, Oregon, United States

Local Institution - 0074, Allentown, Pennsylvania, United States

Local Institution - 0011, Pittsburgh, Pennsylvania, United States

Local Institution - 0040, Pittsburgh, Pennsylvania, United States

Local Institution - 0169, Myrtle Beach, South Carolina, United States

Local Institution - 0009, Chattanooga, Tennessee, United States

Local Institution - 0234, Norfolk, Virginia, United States

Local Institution - 0021, Berazategui, Buenos Aires, Argentina

Local Institution - 0090, Capital Federal, Buenos Aires, Argentina

Local Institution - 0089, Ciudad Autonoma De Buenos Aire, Buenos Aires, Argentina

Local Institution - 0022, Ciudad Autónoma de BuenosAires, Buenos Aires, Argentina

Local Institution - 0102, Viedma, RIO Negro, Argentina

Local Institution - 0020, San Miguel De Tucuman, Tucuman, Argentina

Local Institution - 0048, Liverpool, New South Wales, Australia

Local Institution - 0047, St. Leonards, New South Wales, Australia

Local Institution - 0046, Waratah, New South Wales, Australia

Local Institution - 0050, Elizabeth Vale, South Australia, Australia

Local Institution - 0184, Frankston, Victoria, Australia

Local Institution - 0175, Perth, Western Australia, Australia

Local Institution - 0133, Linz, , Austria

Local Institution - 0136, Salzburg, , Austria

Local Institution - 0132, Vienna, , Austria

Local Institution - 0183, Wien, , Austria

Local Institution - 0029, Hasselt, , Belgium

Local Institution - 0027, Liege, , Belgium

Local Institution - 0071, Ijui, RIO Grande DO SUL, Brazil

Local Institution - 0072, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution - 0070, Barretos, Sao Paulo, Brazil

Local Institution - 0073, Cerqueira Cesar, SAO Paulo, Brazil

Local Institution - 0231, Rio De Janeiro, , Brazil

Local Institution - 0100, São Paulo, , Brazil

Local Institution - 0139, Edmonton, Alberta, Canada

Local Institution - 0109, Montreal, Quebec, Canada

Local Institution - 0112, Sherbrooke, Quebec, Canada

Local Institution - 0101, Montreal, , Canada

Local Institution - 0099, Santiago, Metropolitana, Chile

Local Institution - 0038, Vina Del Mar, Valparaiso, Chile

Local Institution - 0137, Temuco, , Chile

Local Institution - 0191, Beijing, Beijing, China

Local Institution - 0206, Beijing, Beijing, China

Local Institution - 0192, Beijing, Beijing, China

Local Institution - 0210, Chongqing, Chongqing, China

Local Institution - 0198, Fuzhou, Fujian, China

Local Institution - 0222, Guangzhou, Guangdong, China

Local Institution - 0203, Guangzhou, Guangdong, China

Local Institution - 0227, Nanning, Guangxi, China

Local Institution - 0196, Wuhan, Hubei, China

Local Institution - 0220, Nanjing, Jiangsu, China

Local Institution - 0204, Nanjing, Jiangsu, China

Local Institution - 0223, Nanchang, Jiangxi, China

Local Institution, Xi'an, Shan3xi, China

Local Institution - 0212, Yantai, Shandong, China

Local Institution - 0193, Shanghai, Shanghai, China

Local Institution - 0202, Shanghai, Shanghai, China

Local Institution - 0199, Shanghai, Shanghai, China

Local Institution - 0217, Shanghai, Shanghai, China

Local Institution - 0229, Chengdu, Sichuan, China

Local Institution - 0219, Chengdu, Sichuan, China

Local Institution - 0221, Hangzhou, Zhejiang, China

Local Institution - 0195, Hangzhou, Zhejiang, China

Local Institution - 0230, Wenzhou, Zhejiang, China

Local Institution - 0092, Bogota, , Colombia

Local Institution - 0093, Floridablanca, , Colombia

Local Institution - 0091, Medellin, , Colombia

Local Institution - 0108, Aalborg, , Denmark

Local Institution - 0106, Aarhus N, , Denmark

Local Institution - 0107, Copenhagen, , Denmark

Local Institution - 0233, Clermont-ferrand, , France

Local Institution - 0115, La Roche-sur-Yon, , France

Local Institution - 0080, Marseille Cedex 9, , France

Local Institution - 0081, Paris, , France

Local Institution - 0113, Strasbourg, , France

Local Institution - 0097, Suresnes, , France

Local Institution - 0098, Villejuif, , France

Local Institution - 0131, Chemnitz, , Germany

Local Institution - 0125, Essen, , Germany

Local Institution - 0127, Greifswald, , Germany

Local Institution - 0126, Hamburg, , Germany

Local Institution - 0124, Heidelberg, , Germany

Local Institution - 0123, Jena, , Germany

Local Institution - 0188, Marburg, , Germany

Local Institution - 0128, Muenster, , Germany

Local Institution - 0122, Munich, , Germany

Local Institution - 0185, Nuernberg, , Germany

Local Institution - 0130, Regensburg, , Germany

Local Institution - 0129, Stuttgart, , Germany

Local Institution - 0110, Athens, , Greece

Local Institution - 0111, Thessaloniki, , Greece

Local Institution - 0054, Wilton, Cork, Ireland

Local Institution - 0052, Dublin, , Ireland

Local Institution - 0118, Haifa, , Israel

Local Institution - 0121, Jerusalem, , Israel

Local Institution - 0120, Ramat Gan, , Israel

Local Institution - 0119, Zerifin, , Israel

Local Institution - 0088, Arezzo, , Italy

Local Institution - 0197, Bergamo, , Italy

Local Institution - 0082, Milano, , Italy

Local Institution - 0084, Pisa, , Italy

Local Institution - 0189, Reggio Emilia, , Italy

Local Institution - 0085, Roma, , Italy

Local Institution - 0086, Roma, , Italy

Local Institution - 0083, Siena, , Italy

Local Institution - 0142, Akita-shi, Akita, Japan

Local Institution - 0144, Hirosaki, Aomori, Japan

Local Institution - 0162, Fukuoka-shi, Fukuoka, Japan

Local Institution - 0161, Sapporo-shi, Hokkaido, Japan

Local Institution - 0160, Sapporo, Hokkaido, Japan

Local Institution - 0148, Tsukuba-shi, Ibaraki, Japan

Local Institution - 0163, Nagasaki-shi, Nagasaki, Japan

Local Institution - 0150, Niigata-shi, Niigata, Japan

Local Institution - 0141, Okayama-city, Okayama, Japan

Local Institution - 0149, Osakasayama, Osaka, Japan

Local Institution - 0151, Hamamatasu, Shizuoka, Japan

Local Institution - 0146, Bunkyo-ku, Tokyo, Japan

Local Institution - 0145, Shinjuku-Ku, Tokyo, Japan

Local Institution - 0147, Shinjuku-ku, Tokyo, Japan

Local Institution - 0143, Chiba, , Japan

Local Institution - 0164, Osaka, , Japan

Local Institution - 0155, Seongnam-si, , Korea, Republic of

Local Institution - 0154, Seoul, , Korea, Republic of

Local Institution - 0152, Seoul, , Korea, Republic of

Local Institution - 0156, Seoul, , Korea, Republic of

Local Institution - 0138, Df, Distrito Federal, Mexico

Local Institution - 0034, Mexico City, Distrito Federal, Mexico

Local Institution - 0116, Mexico, Distrito Federal, Mexico

Local Institution - 0039, Mexico, Distrito Federal, Mexico

Local Institution - 0035, Guadalajara, Jalisco, Mexico

Local Institution - 0032, Monterrey, Nuevo Leon, Mexico

Local Institution - 0069, Amsterdam, , Netherlands

Local Institution - 0068, Maastrict, , Netherlands

Local Institution - 0041, Nijmegen, , Netherlands

Local Institution - 0043, Lima, , Peru

Local Institution - 0055, Gdansk, , Poland

Local Institution - 0057, Lodz, , Poland

Local Institution - 0187, Warsaw, , Poland

Local Institution - 0058, Wroclaw, , Poland

Local Institution - 0186, Wroclaw, , Poland

Local Institution - 0182, Bucuresti, , Romania

Local Institution - 0096, Craiova, , Romania

Local Institution - 0078, Floresti, , Romania

Local Institution - 0181, Timisoara, Timis, , Romania

Local Institution - 0140, Moscow, , Russian Federation

Local Institution - 0031, Saint-Petersburg, , Russian Federation

Local Institution - 0067, Badalona-barcelona, , Spain

Local Institution - 0066, Barcelona, , Spain

Local Institution - 0064, Madrid, , Spain

Local Institution - 0062, Madrid, , Spain

Local Institution - 0063, Madrid, , Spain

Local Institution - 0232, Santander, , Spain

Local Institution - 0065, Sevilla, , Spain

Local Institution - 0105, Lund, , Sweden

Local Institution - 0134, Basel, , Switzerland

Local Institution - 0135, Zuerich, , Switzerland

Local Institution - 0158, Kaohsiung, , Taiwan

Local Institution - 0159, Taichung, , Taiwan

Local Institution - 0153, Taipei, , Taiwan

Local Institution - 0025, Manchester, Greater Manchester, United Kingdom

Local Institution - 0076, Edinburgh, Midlothian, United Kingdom

Local Institution - 0024, Sutton, Surrey, United Kingdom

Local Institution - 0059, Sheffield, Yorkshire, United Kingdom

Local Institution - 0036, London, , United Kingdom

Local Institution - 0114, London, , United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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