Spots Global Cancer Trial Database for A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin
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Trial Identification
Brief Title: A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin
Official Title: A Randomized Phase 3 Study of Nivolumab Plus Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin in Subjects With Unresectable Advanced, Recurrent or Metastatic Previously Untreated Esophageal Squamous Cell Carcinoma
Study ID: NCT03143153
Conditions
Study Description
Brief Summary: The main purpose of this study is to compare how long subjects with esophageal cancer live overall or live without disease progression after receiving nivolumab and ipilimumab or nivolumab combined with fluorouracil plus cisplatin versus fluorouracil plus cisplatin
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Southern Cancer Center, Inc., Mobile, Alabama, United States
Arizona Cancer Center, Tucson, Arizona, United States
Usc/Norris Comprehensive Cancer Center, Los Angeles, California, United States
Rocky Mountain Cancer Centers, Denver, Colorado, United States
University Of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
Miami Cancer Institute at Baptist Health, Inc., Miami, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
Winship Cancer Institute, Atlanta, Georgia, United States
Northwest Georgia Oncology Center, P.C., Marietta, Georgia, United States
Hackensack Meridian Jersey Shore University Medical Center, Neptune, New Jersey, United States
Oncology Associates Of Oregon, Pc, Eugene, Oregon, United States
Northwest Cancer Specialists, P.C., Portland, Oregon, United States
Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States
Local Institution - 0028, Houston, Texas, United States
Oncology & Hematology Associates Of Southwest Virginia, Inc., Roanoke, Virginia, United States
Local Institution - 0203, Morgantown, West Virginia, United States
Local Institution - 0050, Capital Federal, Buenos Aires, Argentina
Local Institution - 0086, Rosario, Santa FE, Argentina
Local Institution - 0048, Buenos Aires, , Argentina
Local Institution - 0087, La Rioja, , Argentina
Local Institution - 0232, Tamworth, New South Wales, Australia
Local Institution - 0011, Douglas, Queensland, Australia
Local Institution - 0010, Murdoch, Western Australia, Australia
Local Institution - 0241, Salzburg, , Austria
Local Institution - 0017, Salvador, Bahia, Brazil
Local Institution - 0227, Ipatinga, Minas Gerais, Brazil
Local Institution - 0021, Ijui, RIO Grande DO SUL, Brazil
Local Institution - 0016, Porto Alegre, RIO Grande DO SUL, Brazil
Local Institution - 0019, Barretos, Sao Paulo, Brazil
Local Institution - 0226, Jau, Sao Paulo, Brazil
Local Institution - 0018, São José do Rio Preto, São Paulo, Brazil
Local Institution - 0228, Rio de Janeiro, , Brazil
Local Institution - 0020, Sao Paulo, , Brazil
Local Institution - 0095, Moncton, New Brunswick, Canada
Local Institution - 0082, Montreal, Quebec, Canada
Local Institution - 0222, Montreal, Quebec, Canada
Local Institution - 0037, Trois-Rivieres, Quebec, Canada
Local Institution - 0053, Santiago, Metropolitana, Chile
Local Institution - 0214, Santiago, Metropolitana, Chile
Local Institution - 0207, Hefei, Anhui, China
Local Institution - 0197, Hefei, Anhui, China
Local Institution - 0182, Beijing, Beijing, China
Local Institution - 0179, Beijing, Beijing, China
Local Institution - 0216, Beijing, Beijing, China
Local Institution - 0217, Fuzhou, Fujian, China
Local Institution - 0219, Fuzhou, Fujian, China
Local Institution - 0199, Shantou, Guangdong, China
Local Institution - 0185, Harbin, Heilongjiang, China
Local Institution - 0193, Zhengzhou, Henan, China
Local Institution - 0195, Zhengzhou, Henan, China
Local Institution - 0194, Zhengzhou, Henan, China
Local Institution - 0249, Changsha, Hunan, China
Local Institution - 0212, Changsha, Hunan, China
Local Institution - 0201, Nanjing, Jiangsu, China
Local Institution - 0180, Changchun, Jilin, China
Local Institution - 0183, Xi'an, Shan3xi, China
Local Institution - 0215, Shanghai, Shanghai, China
Local Institution - 0200, Shanghai, Shanghai, China
Local Institution - 0184, Hangzhou, Zhejiang, China
Local Institution - 0247, Linhai, Zhejiang, China
Local Institution - 0220, Shenyang, , China
Local Institution - 0248, Xi'An, , China
Local Institution - 0059, Bogota, , Colombia
Local Institution - 0058, Medellin, , Colombia
Local Institution - 0224, Monteria, , Colombia
Local Institution - 0094, Pereira, , Colombia
Local Institution - 0083, Brno, , Czechia
Local Institution - 0008, Brno, , Czechia
Local Institution - 0006, Novy Jicin, , Czechia
Local Institution - 0099, Odense, , Denmark
Local Institution - 0116, Lille, Nord, France
Local Institution - 0114, Caen, , France
Local Institution - 0112, Montpellier, , France
Local Institution - 0113, Rennes Cedex, , France
Local Institution - 0242, Toulouse, , France
Local Institution - 0115, Villejuif, , France
Local Institution - 0035, Hong Kong, , Hong Kong
Local Institution - 0070, Kowloon, , Hong Kong
Local Institution - 0085, Bergamo, , Italy
Local Institution - 0039, Milano, , Italy
Local Institution - 0084, Padova, , Italy
Local Institution - 0240, Pisa, , Italy
Local Institution - 0152, Akita-shi, Akita, Japan
Local Institution - 0104, Hirosaki-shi, Aomori, Japan
Local Institution - 0173, Kashiwa-shi, Chiba, Japan
Local Institution - 0169, Matsuyama-shi, Ehime, Japan
Local Institution - 0119, Matsuyama-shi, Ehime, Japan
Local Institution - 0174, Fukuoka-shi, Fukuoka, Japan
Local Institution - 0142, Fukuoka-shi, Fukuoka, Japan
Local Institution - 0103, Fukushima-shi, Fukushima, Japan
Local Institution - 0154, Gifu City, Gifu, Japan
Local Institution - 0176, Ota, Gunma, Japan
Local Institution - 0100, Hiroshima-Shi, Hiroshima, Japan
Local Institution - 0111, Sapporo-shi, Hokkaido, Japan
Local Institution - 0170, Akashi-shi, Hyogo, Japan
Local Institution - 0118, Kobe-shi, Hyogo, Japan
Local Institution - 0172, Kobe, Hyogo, Japan
Local Institution - 0171, Kanazawa, Ishikawa, Japan
Local Institution - 0229, Kagoshima-shi, Kagoshima, Japan
Local Institution - 0127, Isehara, Kanagawa, Japan
Local Institution - 0109, Kawasaki-shi, Kanagawa, Japan
Local Institution - 0105, Sagamihara-shi, Kanagawa, Japan
Local Institution - 0147, Yokohama-shi, Kanagawa, Japan
Local Institution - 0117, Yokohama-shi, Kanagawa, Japan
Local Institution - 0141, Kumamoto-shi, Kumamoto, Japan
Local Institution - 0120, Kamigyo-ku, Kyoto, Japan
Local Institution - 0144, Sendai, Miyagi, Japan
Local Institution - 0146, Niigata-shi, Niigata, Japan
Local Institution - 0135, Kurashiki-shi, Okayama, Japan
Local Institution - 0137, Okayama-shi, Okayama, Japan
Local Institution - 0221, Hirakata, Osaka, Japan
Local Institution - 0138, Osaka-shi, Osaka, Japan
Local Institution - 0098, Osakasayama, Osaka, Japan
Local Institution - 0107, Suita, Osaka, Japan
Local Institution - 0139, Takatsuki City, Osaka, Japan
Local Institution - 0230, Hidaka-shi, Saitama, Japan
Local Institution - 0175, Kitaadachi-gun, Saitama, Japan
Local Institution - 0143, Sunto-gun, Shizuoka, Japan
Local Institution - 0148, Shimotsuga-gun, Tochigi, Japan
Local Institution - 0106, Bunkyo-ku, Tokyo, Japan
Local Institution - 0110, Bunkyo-ku, Tokyo, Japan
Local Institution - 0128, Chuo-ku, Tokyo, Japan
Local Institution - 0136, Chuo-ku, Tokyo, Japan
Local Institution - 0126, Koto-ku, Tokyo, Japan
Local Institution - 0156, Minato-ku, Tokyo, Japan
Local Institution - 0245, Ota-ku, Tokyo, Japan
Local Institution - 0140, Shinagawa-ku, Tokyo, Japan
Local Institution - 0196, Shinjuku-Ku, Tokyo, Japan
Local Institution - 0155, Shinjuku-ku, Tokyo, Japan
Local Institution - 0231, Toyama-shi, Toyama, Japan
Local Institution - 0178, Wakayama-shi, Wakayama, Japan
Local Institution - 0238, Ube-shi, Yamaguchi, Japan
Local Institution - 0101, Chiba, , Japan
Local Institution - 0153, Chiba, , Japan
Local Institution - 0145, Kyoto, , Japan
Local Institution - 0108, Shizuoka, , Japan
Local Institution - 0129, Seongnam-si, Kyǒnggi-do, Korea, Republic of
Local Institution - 0165, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of
Local Institution - 0166, Busan, , Korea, Republic of
Local Institution - 0150, Daegu, , Korea, Republic of
Local Institution - 0149, Daejeon, , Korea, Republic of
Local Institution - 0236, Jeonju-si, , Korea, Republic of
Local Institution - 0235, Seoul, , Korea, Republic of
Local Institution - 0130, Seoul, , Korea, Republic of
Local Institution - 0177, Seoul, , Korea, Republic of
Local Institution - 0168, Seoul, , Korea, Republic of
Local Institution - 0151, Seoul, , Korea, Republic of
Local Institution - 0131, Seoul, , Korea, Republic of
Local Institution - 0123, Seoul, , Korea, Republic of
Local Institution - 0157, Ulsan, , Korea, Republic of
Local Institution - 0090, Tuxtla Gutierrez, Chiapas, Mexico
Local Institution - 0102, Mexico, Distrito Federal, Mexico
Local Institution - 0071, Merida, Yucatan, Mexico
Local Institution - 0234, San Luis Potosi, , Mexico
Local Institution - 0092, Callao, , Peru
Local Institution - 0060, Lima, , Peru
Local Institution - 0093, Lima, , Peru
Local Institution - 0024, Lublin, , Poland
Local Institution - 0022, Warszawa, , Poland
Local Institution - 0243, Porto, , Portugal
Local Institution - 0081, Bucuresti, , Romania
Local Institution - 0079, Cluj-Napoca, , Romania
Local Institution - 0076, Craiova, , Romania
Local Institution - 0080, Suceava, , Romania
Local Institution - 0089, Moscow, , Russian Federation
Local Institution - 0088, St Petersburg, , Russian Federation
Local Institution - 0033, Singapore, Central Singapore, Singapore
Local Institution - 0034, Singapore, , Singapore
Local Institution - 0063, Barcelona, , Spain
Local Institution - 0062, Madrid, , Spain
Local Institution - 0161, Tainan, TNN, Taiwan
Local Institution - 0158, Changhua, , Taiwan
Local Institution - 0163, Kaohsiung County, , Taiwan
Local Institution - 0167, Kaohsiung, , Taiwan
Local Institution - 0133, Kaohsiung, , Taiwan
Local Institution - 0164, Keelung, , Taiwan
Local Institution - 0132, Taichung, , Taiwan
Local Institution - 0160, Tainan, , Taiwan
Local Institution - 0124, Taipei, , Taiwan
Local Institution - 0162, Taipei, , Taiwan
Local Institution - 0134, Taipei, , Taiwan
Local Institution - 0159, Taoyuan, , Taiwan
Local Institution - 0096, Ankara, , Turkey
Local Institution - 0125, Diyarbakır, , Turkey
Local Institution - 0122, Edrine, , Turkey
Local Institution - 0069, London, Greater London, United Kingdom
Local Institution - 0066, London, Greater London, United Kingdom
Local Institution - 0031, Manchester, Greater Manchester, United Kingdom
Local Institution - 0237, London, , United Kingdom
Local Institution - 0029, Surrey, , United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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