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Spots Global Cancer Trial Database for A Study to Evaluate the Safety and Efficacy of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Participants With High Grade Primary Central Nervous System (CNS) Malignancies

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Trial Identification

Brief Title: A Study to Evaluate the Safety and Efficacy of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Participants With High Grade Primary Central Nervous System (CNS) Malignancies

Official Title: Phase Ib /II Clinical Trial of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Subjects With High Grade Primary CNS Malignancies

Study ID: NCT03130959

Interventions

Nivolumab
Ipilimumab

Study Description

Brief Summary: The purpose of this study is to determine the safety and effectiveness of nivolumab alone and in combination with ipilimumab in pediatric patients with high grade primary central nervous system (CNS) malignancies.

Detailed Description:

Keywords

Eligibility

Minimum Age: 6 Months

Eligible Ages: CHILD, ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Local Institution - 0057, Los Angeles, California, United States

Local Institution - 0016, Aurora, Colorado, United States

Local Institution - 0046, Gainesville, Florida, United States

Local Institution - 0011, Chicago, Illinois, United States

Local Institution - 0005, Baltimore, Maryland, United States

Local Institution - 0043, Boston, Massachusetts, United States

Local Institution - 0044, Saint Louis, Missouri, United States

Local Institution - 0004, New York, New York, United States

Local Institution - 0017, New York, New York, United States

Cincinnati Children'S Hospital Medical Center, Cincinnati, Ohio, United States

Local Institution - 0066, Philadelphia, Pennsylvania, United States

Local Institution, Charleston, South Carolina, United States

Local Institution - 0012, Memphis, Tennessee, United States

Local Institution - 0042, Houston, Texas, United States

Local Institution - 0022, Randwick, New South Wales, Australia

Local Institution - 0035, Sth Brisbane, Queensland, Australia

Local Institution, Clayton, Victoria, Australia

Local Institution - 0034, Parkville, Victoria, Australia

Local Institution - 0033, Nedlands, Western Australia, Australia

Local Institution - 0052, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution - 0051, Barretos, Sao Paulo, Brazil

Local Institution - 0053, Ribeirao Preto, Sao Paulo, Brazil

Local Institution - 0049, Sao Paulo, , Brazil

Local Institution - 0050, Sao Paulo, , Brazil

Local Institution - 0021, Toronto, Ontario, Canada

Local Institution - 0001, Montreal, Quebec, Canada

Local Institution - 0002, Quebec, , Canada

Local Institution - 0028, Angers, , France

Local Institution - 0029, Bordeaux Cedex, , France

Local Institution - 0027, Lille, , France

Local Institution - 0025, Lyon, , France

Local Institution - 0024, Marseille, , France

Local Institution - 0023, Paris, , France

Local Institution - 0064, Vandoeuvre les Nancy, , France

Local Institution - 0026, VIillejuif, , France

Local Institution - 0060, Essen, , Germany

Local Institution - 0061, Hamburg, , Germany

Local Institution - 0063, Heidelberg, , Germany

Local Institution - 0062, Wuerzburg, , Germany

Local Institution - 0018, Hong Kong, , Hong Kong

Local Institution - 0059, Haifa, , Israel

Local Institution - 0058, Ramat Gan, , Israel

Local Institution - 0007, Rotterdam, , Netherlands

Local Institution - 0008, Utrecht, , Netherlands

Local Institution - 0067, Oslo, , Norway

Local Institution - 0047, Warszawa, , Poland

Local Institution - 0048, Moscow, , Russian Federation

Local Institution - 0037, Esplugues de Llobregat, , Spain

Local Institution - 0038, Madrid, , Spain

Local Institution - 0036, Valencia, , Spain

Local Institution - 0065, Solna, , Sweden

Local Institution - 0010, London, Greater London, United Kingdom

Local Institution - 0013, Liverpool, Merseyside, United Kingdom

Local Institution - 0015, Newcastle Upon Tyne, Tyne And Wear, United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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