Spots Global Cancer Trial Database for Weekly Sirolimus Therapy
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Trial Identification
Brief Title: Weekly Sirolimus Therapy
Official Title: Weekly Sirolimus Therapy for the Treatment of Venous and Lymphatic Malformations
Study ID: NCT04861064
Interventions
Study Description
Brief Summary: In current practice, options for venous and lymphatic malformations remain limited. Recently an oral medication, sirolimus, has been found to benefit patients when taken once or twice a day for several months. Unfortunately there are many side effects associated with this medication, some of which can be severe including, neutropenia, oral ulcerations, and lab abnormalities. The purpose of this study is to determine if once weekly dosed sirolimus will be effective for the treatment of venous and lymphatic malformations. Additionally, the study will evaluate patient satisfaction and identify adverse effects. Participants will be on the medication for 6 months with an option to continue after this time period.
Detailed Description:
Keywords
Eligibility
Minimum Age: 2 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Medical University of South Carolina, Charleston, South Carolina, United States
Contact Details
Name: Chelsea Shope, MSCR
Affiliation: Medical University of South Carolina
Role: PRINCIPAL_INVESTIGATOR
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