Spots Global Cancer Trial Database for Screening for Occult Malignancy in Idiopathic Venous Thromboembolism
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Trial Identification
Brief Title: Screening for Occult Malignancy in Idiopathic Venous Thromboembolism
Official Title:
Study ID: NCT00361647
Conditions
Interventions
Study Description
Brief Summary: Prospective controlled randomized study. Aim of this study is to assess the feasibility and sensitivity of CT scanning of the thorax, abdomen and pelvis for the detection of occult cancer in patients with idiopathic venous thromboembolism. Patients presenting with acute idiopathic venous thromboembolism, free from already known cancer and in whom a routine battery screening has excluded the presence of cancer, are randomized to receive either a CT scanning of the thorax, abdomen and pelvis (completed by mammography if not already performed in the past year, and by gastroscopy and/or colonoscopy in patients with positive hemoccult) or a diagnostic programme freely decided by attending physicians. Patients of either group in whom the search for cancer is negative are followed-up for two years to register the development of clinically symptomatic malignant disease. The rate of cancer detection and that of cancer development are compared between the two study groups.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua, Padua, , Italy
Contact Details
Name: Paolo Prandoni, MD, PhD
Affiliation: Department of Medical and Surgical Sciences, University of Padua, Italy
Role: PRINCIPAL_INVESTIGATOR
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