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The patients will be injected with glycerol using a new neuronavigation-based technique in the trigeminal ganglion.

Erling A Tronvik, PhD, MD

Trigeminal neuralgia is one of the strongest pains known to humans. Some patients do not have enough effect with the available pharmaceutical treatments and are offered a type of surgery, which involves the injection of glycerol in a nerve structure called trigeminal ganglion. The researchers will do a pilot study on 10 patients with a new surgical technique using neuronavigation. The researchers believe that this new neuronavigation-based system can improve the precision of the technique and reduce the risk for complications.

Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique

Number of adverse events and number of participants with adverse events after glycerol injection in the trigeminal ganglion and severity of adverse events by the method used. Registration of any adverse events categorized by probable relationship to drug or the procedure. Data obtained from the headache diaries as well as open questions during consultations.

expressed as score on Visual analogue scale (VAS) for pain

expressed by means of patient global impression of change questionnaire (PGIC)

St. Olavs Hospital

Norwegian University of Science and Technology

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique	NCT02624661	Trigeminal Neur... Headache Disord...	Glycerol	18 Years - 80 Years	Norwegian University of Science and Technology
Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique	NCT02624661	Trigeminal Neur... Headache Disord...	Glycerol	18 Years - 80 Years	Norwegian University of Science and Technology

Spots Global Cancer Trial Database for trigeminal ganglion