Symptoms and General Pathology

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Port-Wine Stain

Neoplasms, Vascular Tissue

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Congenital Abnormalities

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Skin Diseases

Yi Ji

Yi Ji, MD, PhD

Siyuan Chen

Bo Xiang, MD, PhD

Lin Zhong, MD

Zhicheng Xu, MD

Kaiying Yang, MD

Suhua Peng, MD

The primary purpose of this study is to identify the clinical characteristics of infantile hemangioma (IH) in our single center in China. The second objective of the study is to identify the clinical features of infantile hepatic hemangioma (IHH) and ulceration in patients with IHs.

Infantile hemangioma (IH) is the most common benign tumor of infancy with an estimated prevalence of 4%-5%. IHs may be presented in any part of body including the visceral organs, but are preferentially located on the face, head and neck area. IHs exhibit a characteristic life cycle consisting of a rapid proliferating phase within the first year of life followed by a slowly involuted phase lasting for up to five years. Although most resolve over time without major sequelae, a significant subset can result in severe complications including disfiguring and ulceration, some even could impair organ functions and threaten patients' life. Risk factors of IHs have been identified including multiple gestation, low birth weight, prematurity, white race, eclampsia and placental abnormalities. However, the exact occurrence, clinical features and risk factors of IHs is still unknown in Chinese patients because of the lack of large scale of prospective studies. In addition, characteristics of ulceration of IHs and infantile hepatic hemangiomas (IHHs) are also not well documented. Therefore, it's important to perform this prospective study to determine the clinical features of Chinese patients with IHs, and this study will also make contributions to the prevents, diagnoses and treatments of IHs.

Clinical Characteristics of Infantile Hemangioma

Clinical Characteristics of Infantile Hemangioma: a Prospective Study

Clinical characteristics of infantile hemangioma. Phase of growth include proliferation, plateau and involution phase. Morphologic subtypes include localized, segmental, indeterminate and multifocal type.

Demographic characteristics in patients with IH.

Demographic characteristics in patients with infantile hepatic hemangioma.

Clinical characteristics of infantile hepatic hemangioma

Clinical characteristics of ulcerated IHs. Phase of growth include proliferation, plateau and involution, and morphologic subtypes include localized, segmental, indeterminate and multifocal type.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Clinical Characteristics of Infantile Hemangioma	NCT03331744	Hemangioma		- 6 Years	West China Hospital
Clinical Characteristics of Infantile Hemangioma	NCT03331744	Hemangioma		- 6 Years	West China Hospital

Spots Global Cancer Trial Database for ulcerated infantile hemangioma