Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Behaviors and Mental Disorders

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

Quality of Life

new patients with bladder cancer scheduled for radical cystectomy and subsequent conduit diversion

new patients with bladder cancer scheduled for radical cystectomy and subsequent orthotopic neobladder

All eligible patients who agree to participate will be asked to fulfill three different validated health-related quality of life questionnaires (EORTC-QLQ-C30/BLM, FACT-BL and BCI) prior to surgery and at 3, 6, 12, 18 months postoperatively.

validated health-related quality of life questionnaires

Xiaoping Zhang, MD, PhD

Hangchuan Shi, MD

Xiaoping Zhang, MD,PhD

Xiang Li, MD

The aim of this study is to compare the health-related quality of life (HRQoL) between patients underwent conduit diversion and orthotopic neobladder after radical cystectomy. The investigators plan to use validated HRQoL questionnaires to learn about how the different urinary diversion operations affect the HRQoL of people living with bladder cancer. The findings from this study may help doctors and patients choosing the proper operation type.

Compare the Quality of Life Between Patients With Conduit Diversions or Orthotopic Neobladders

A Prospective and Comparative Study of Health-related Quality of Life (HRQoL) in Patients With Conduit Diversion or Orthotopic Neobladder

The aim is to compare three various validated tools of HRQoL to study their relative contributions in accounting for variance in prediction of patient HRQoL.

The three validated tools of HRQoL are EORTC-QLQ-C30/BLM (The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire/bladder cancer module), FACT-BL (Functional Assessment of Cancer Therapy-Bladder cancer) and BCI (Bladder Cancer Index).

The two groups are conduit diversion group and orthotopic neobladder group.

Longitudinally learn about the changes of each individual patient HRQoL after urinary diversion and compare the changes of two groups, i.e. conduit diversion group and orthotopic neobladder group.

Supplement the assessment by interviewing the patients with some lab and image examinations, such as renal function tests, liver function tests, urine culture, urine cytology, chest radiography, ultrasound of kidney, ureter and bladder (KUB) etc.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Compare the Quality of Life Between Patients With Conduit Diversions or Orthotopic Neobladders	NCT02174185	Bladder Cancer	validated healt...	18 Years -	Huazhong University of Science and Technology
Compare the Quality of Life Between Patients With Conduit Diversions or Orthotopic Neobladders	NCT02174185	Bladder Cancer	validated healt...	18 Years -	Huazhong University of Science and Technology

Spots Global Cancer Trial Database for validated questionnaire