Urinary Tract, Sexual Organs, and Pregnancy Conditions

Symptoms and General Pathology

All Conditions

Neoplasms

Urinary Bladder, Overactive

Prostatic Neoplasms

Urination Disorders

Urinary Bladder Diseases

Urologic Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Male Urogenital Diseases

Lower Urinary Tract Symptoms

Urological Manifestations

Urological Agents

All Drugs and Chemicals

Solifenacin Succinate

Muscarinic Antagonists

Cholinergic Antagonists

Cholinergic Agents

Neurotransmitter Agents

Solifenacin succinate, 5mg or 10 mg once daily

Solifenacin succinate

Placebo

Sanjay Mehta, M.D.

The purpose of this study is to determine if Vesicare (Solifenacin succinate) is effective in treating over-active bladder symptoms during radiation therapy of the prostate.

This is a randomized double blind placebo controlled flexible dose 12 week study. Following screening, subjects will receive their first dose of study medication following completion of AUASS questionnaire on the first day of radiation treatment (baseline) and will continue for twelve weeks. Subjects will be started on 5 mg of study medication. The AUASS will be completed at baseline, weeks 4, 8 and 12. A 16 week visit conducted over a phone interview.

VESIcare For Improving OAB Symptoms in Patients Undergoing IGRT of the Prostate

A Pilot Study to Assess the Safety and Efficacy of Solifenacin (VESIcare) for Improving Urinary and Bladder Functions in Patients Undergoing Radiation Therapy of the Prostate

The AUASS score range is 1-7 (mild), 8-19 (moderate) and 20-35 (severe). The AUASS asks 7 questions scored 0-5, the scores are summed for the total score.

Astellas Pharma US, Inc.

Advanced Research Network

Solifenacin succinate, 5mg or 10 mg once daily

Solifenacin succinate

Total

Age, Continuous

Age, Categorical

Sex: Female, Male

United States

Region of Enrollment

Early termination leading to small numbers of subjects analyzed.

Dr. Sanjay Mehta

Change From Baseline to End of Study Measured by the American Urology Association Symptom Score Questionnaire (AUASS).

Overall Study

Spots Global Cancer Trial Database for vesicare

Every month we try and update this database with for vesicare cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for vesicare

Every month we try and update this database with for vesicare cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for vesicare cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.