Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Rare Diseases

Uterine Cervical Dysplasia

Precancerous Conditions

Uterine Cervical Diseases

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Cervical Intraepithelial Neoplasia

The LLETZ procedure will be performed using a videocolposcopy

The LLETZ procedure will be performed using a binocular colposcope

Loop procedure using a videocolposcope in order to see and remove the abnormal cervical tissue

LLETZ with videocolposcope

Loop procedure using a binocular colposcope in order to see and remove the abnormal cervical tissue

LLETZ with binocular colposcope

Ziad Hilal, M.D.

To assess the benefits of performing large Loop excision of the transformation Zone (LLETZ) using videocolposcopy compared to binocular colposcopy.

LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy

Performance of Large Loop Excision of the Transformation Zone Using Videocolposcopy Versus Binocular Colposcopy in Women With Cervical Dysplasia: a Randomized Controlled Trial.

the resected cone mass will be quantified by weighing the removed tissue with a precision scale located in the operating room

Resection margin is judge as "R0" if abnormal cells are not found in the margin of the biopsy or "R1" if abnormal cells remain in the margin of the biopsy. The histopathological examination will be done by an Independent pathologist

the time from the beginning of the Operation (start of the electrosurgical method) until the end of the operation (the end of hemostatic interventions) will be measured in minutes

Operative complications defined as necessity to intervene therapeutically up to 14 days postoperatively

surgeons will count the number of the surgical specimen (1 vs. \>1)

The circumference of the surgical specimens will be measured in cm

The length of The surgical specimens will be measured in cm

The thickness of The surgical specimens will be measured in cm

surgeons will score their preference regarding the surgical method using an 11-step visual analogue scale (VAS) for ,(ranging from 0 (,very easy') to 10 (,very difficult')

surgeons will score their preference regarding the surgical method using an 11-step visual analogue scale (VAS) for ,satisfaction with the device' (ranging from 0 (,very satisfied') to 10 (,absolutely not satisfied')

the time until complete hemostasis as judged by the surgeon has been achieved, will be measured in seconds

intraoperative blood loss will be measured using the difference in serum hemoglobin one day prior to surgery and within 5 hours postoperatively

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy	NCT04326049	Uterine Cervica...	LLETZ with vide... LLETZ with bino...	18 Years -	Zydolab - Institute of Cytology and Immune Cytochemistry
LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy	NCT04326049	Uterine Cervica...	LLETZ with vide... LLETZ with bino...	18 Years -	Zydolab - Institute of Cytology and Immune Cytochemistry

Spots Global Cancer Trial Database for videocolposcopy