Neoplasms

Digestive System Diseases

All Conditions

Symptoms and General Pathology

Colonic Neoplasms

Body Weight

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Herbal and Botanical

All Drugs and Chemicals

Cola

The exercise group will perform supervised stationary cycle ergometer exercise 3 times per week for 12 weeks and be progressed from 15 to 45 minutes and 60% to 110% of the power output obtained at V02peak. Resistance training will be completed twice per week and will include exercises for all major muscle groups. The training will progress from 60% to 80% of 1RM over the course of the intervention.

Exercise Training

Usual Care

Kerry Courneya, Ph.D.

Recent studies have suggested that individuals diagnosed with colon cancer who are inactive and/or overweight, may have poorer survival outcomes. Exercise training has been shown to improve fitness and body composition in other cancer survivor groups. The investigators hypothesize that an exercise training program will be a safe, feasible, and effective intervention to improve the fitness and body composition of a group of colon cancer survivors.

The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors

The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors: a Randomized Controlled Trial

AHS Cancer Control Alberta

Skin and Connective Tissue Diseases

Behaviors and Mental Disorders

Breast Neoplasms

Breast Diseases

Skin Diseases

Quality of Life

Aerobic Exercise Training

Resistance Exercise Training

Kerry S Courneya, PhD

The purpose of this study is to compare the effects of two different types of exercise, aerobic exercise training (AET) and resistance exercise training (RET), on quality of life (QoL) in early stage breast cancer survivors receiving chemotherapy. It is hypothesized that both AET and RET would have beneficial effects on QoL.

The study was a prospective, three-armed, randomized controlled trial. Participants were stratified by site (Edmonton, Ottawa, and Vancouver) and planned chemotherapy protocol (taxane-based versus nontaxane-based) and randomly assigned to AET, RET, or usual care (UC) in a 1:1:1 ratio using a random-numbers table. Participants assigned to the AET group were asked to perform aerobic exercise three times per week on a recumbent or upright cycle ergometer, treadmill, or elliptical. Exercise duration began at 15 minutes for weeks 0 through 2, and then systematically increased by 5 minutes every three weeks thereafter to 45 minutes for weeks 18 and beyond. Exercise intensity began at 60% of VO2max for weeks 0 through 2 and then systematically increased by 10% every 6 weeks thereafter to 80% of VO2max for weeks 12 and beyond. Warm-up and cool-down periods consisted of 5 minutes of aerobic activity at the power output of the ventilatory equivalent for oxygen (approximately 50% of peak oxygen consumption). Participants assigned to the RET group were asked to perform resistance exercise three times per week, which consisted of two sets of 10 repetitions of 9 different exercises performed at 60-70% of 1-repetition maximum. The specific exercises were: leg extension, leg curl, calf raises, chest press, latissimus pulldown, overhead press, triceps extension, biceps curls, and modified curl-ups. Resistance was increased by approximately 10% or the next weight level when the participant was able to complete 12 repetitions per set without difficulty.

Effects of Aerobic Exercise Versus Weight Training in Breast Cancer Survivors During Chemotherapy

Comparison of Aerobic Versus Resistance Exercise Training in Enhancing Quality of Life in Early Stage Breast Cancer Survivors Receiving Chemotherapy: A Multi-Centre Randomized Trial

Canadian Breast Cancer Research Alliance

University of Alberta, Physical Education

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors	NCT00813540	Colonic Neoplas...	Exercise Traini... Usual Care	18 Years -	AHS Cancer Control Alberta
Effects of Aerobic Exercise Versus Weight Training in Breast Cancer Survivors During Chemotherapy	NCT00115713	Breast Neoplasm...	Aerobic Exercis... Resistance Exer...	-	University of Alberta, Physical Education
The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors	NCT00813540	Colonic Neoplas...	Exercise Traini... Usual Care	18 Years -	AHS Cancer Control Alberta
Effects of Aerobic Exercise Versus Weight Training in Breast Cancer Survivors During Chemotherapy	NCT00115713	Breast Neoplasm...	Aerobic Exercis... Resistance Exer...	-	University of Alberta, Physical Education

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