Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

All Drugs and Chemicals

Immunomodulating Agents

DC-CIK cells will be used against tumor cells.

γδ T cells will be used against tumor cells.

Combination of γδ T cells/ DC-CIK be used against tumor cells.

DC-CIK

γδ T cells will be used against breast tumor.

γδ T Cell

γδ T/DC-CIK cells will be used against breast tumor.

Combination

In this study, effects of γδT cells on human breast cancer (her2-, er-,pr-) in combination with tumor reducing surgery, for example cryosurgery going to be investigated.

Breast tumor will be removed using tumor reducing surgery such as cryosurgery. PBMC of the patient will be separated from peripheral blood. After making them potential cancer killer γδ T Cell and DC-CIK, they will be infused to the patients as immunotherapy.

Safety and Efficiency of γδ T Cell Against Breast Cancer(Her-, er-, and pr-)

γδ T Cell Immunotherapy for Treatment of Breast Cancer

Jinan University Guangzhou

Fuda Cancer Hospital, Guangzhou

Digestive System Diseases

Gland and Hormone Related Diseases

Rare Diseases

Pancreatic Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Endocrine Gland Neoplasms

Gastrointestinal Diseases

Pancreatic Diseases

Endocrine System Diseases

Pancreatic Cancer

In this group, the patients will receive IRE surgery to control the local tumor under CT .

In this group, the patients will receive multiple high-activity γδ T cell immunotherapies and IRE surgery

IRE surgery

Combination IRE surgery and γδ T cell will be used in Pancreatic Cancer

IRE plus γδ T cells

Jibing Chen, PhD

In this study, effects of γδT cells on human Pancreatic Cancer in combination with tumor reducing surgery, for example IRE going to be investigated.

Pancreatic tumor will be removed using tumor reducing surgery such as IRE. PBMC of the healthy donor will be separated from peripheral blood. After making them potential cancer killer γδ T Cell, they will be infused to the patients as an immunotherapy treatment.

Safety and Efficiency of IRE Plus γδ T Cell Against Locally Advanced Pancreatic Cancer

PFS was defined as the interval between treatment initiation and local relapse

OS was calculated as the interval from treatment initiation to death.

The tumor responses of the enrolled patients were assessed by CT in accordance with RECIST v1.1.Institute Common Terminology Criteria for Adverse Events (v4.0).

The absolute number of CD45-CK+ CD326+ cells was used to quantitate the CTC levels.

The serum concentrations of CA19-9 were evaluated by a chemiluminescent immunoassay before treatment and 90 days after treatment.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Safety and Efficiency of γδ T Cell Against Breast Cancer(Her-, er-, and pr-)	NCT02418481	Breast Cancer	DC-CIK γδ T Cell Combination	18 Years - 75 Years	Fuda Cancer Hospital, Guangzhou
Safety and Efficiency of IRE Plus γδ T Cell Against Locally Advanced Pancreatic Cancer	NCT03180437	Pancreatic Canc...	IRE surgery IRE plus γδ T c...	18 Years - 80 Years	Fuda Cancer Hospital, Guangzhou
Safety and Efficiency of IRE Plus γδ T Cell Against Locally Advanced Pancreatic Cancer	NCT03180437	Pancreatic Canc...	IRE surgery IRE plus γδ T c...	18 Years - 80 Years	Fuda Cancer Hospital, Guangzhou

Spots Global Cancer Trial Database for γδ t cell

Every month we try and update this database with for γδ t cell cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for γδ t cell

Every month we try and update this database with for γδ t cell cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for γδ t cell cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.