Behaviors and Mental Disorders

All Conditions

Rare Diseases

Quality of Life

Oculocerebral Syndrome With Hypopigmentation

Participants will begin a 12-week high-intensity functional training program conducted at CrossFit® in the D, located in downtown Detroit, Northville Athletix in Northville and Five Lakes CrossFit® in Farmington Hills.

12 week pilot intervention study.

Jennifer B Beebe-Dimmer, MPH, PhD.

Tara Baird, M.Ed.

Tara Baird

Jennifer Beebe-Dimmer, MPH, PhD.

This study will introduce cancer survivors to cross-training with the expectation that the program proposed will ultimately result in superior improvements in functional performance, body composition and quality of life compared with the current American Cancer Society (ACS) guidelines for cancer survivors.

A 12-week pilot intervention study introducing a high-intensity functional training program to 100 cancer survivors and evaluate the effects of this program on patient quality of life, functional capacity, and body composition. Response rates will be determined using various recruitment methods and estimate differences in response rates by patient characteristics including race, gender and age. Barriers to participation in the program in contacted patients who do not enroll as well as patients who enroll and do not complete the program will be described, as will participant satisfaction with enrolled participants who complete the program. The goal of this pilot study is to help refine the recruitment and program methods for a larger intervention study to test the superiority of a high-intensity interval functional training program compared with current American Cancer Society guidelines in improving functional capacity, body composition and patient reported quality of life.

Surveys will be completed by each participant weekly and physical assessments will be completed monthly.

C.A.P.A.B.L.E. (Cross-Training and Physical Activity: A Better Life Experience Study)

Does High-Intensity Functional Training Improve Patient Movement and Quality of Life? A Pilot Study of Cross-Training in Cancer Survivors

Enrollment rates will be calculated among those who respond to notices about the study and adherence to the program among those who enroll and to describe reported barriers to participation among respondents who do not ultimately enroll

Physical measures of strength will be assessed by a certified trainer. To assess strength improvements deadlifts (lifting weights from floor to waist) will be performed in 10 lb. increments. A circuit will also be done with strength measures including sit ups and push ups.

Physical measures of flexibility will be assessed by a certified trainer. To assess flexibility sit ups, squats and push up level (floor, knees, on an elevated bar, etc) will be recorded.

Physical measures of cardiovascular strength will be assessed by a certified trainer. To assess cardiovascular strength maximum effort on a stationary bike will be recorded. Additionally, in the circuit, a maximum effort on a rowing machine will be recorded.

Quality of Life will be measured using the Functional Assessment of Cancer Therapy: General (FACT), developed by Dr. David Cella. The FACT-G is 27 items assessing physical, social/ family, emotional and functional well-being. The survey uses a five-point scale from 0 (not at all) to 4 (very much). Scoring the FACT-G is performed through a sum of item scores. Higher scores indicate a better health state.

Changes in body mass index (BMI) - Weight and height will be combined to report BMI in kg/ m2

Motivation to exercise will be collected via a survey

Satisfaction with the program will be collected via a survey

Program adherence will be calculated based on how many sessions each participant attended in the 13 week program, 36 session design.

Height will be collected in meters to use in the calculation of Body Mass Index

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
C.A.P.A.B.L.E. (Cross-Training and Physical Activity: A Better Life Experience Study)	NCT03750981	Cancer Survivor...	12 week pilot i...	18 Years -	Barbara Ann Karmanos Cancer Institute
C.A.P.A.B.L.E. (Cross-Training and Physical Activity: A Better Life Experience Study)	NCT03750981	Cancer Survivor...	12 week pilot i...	18 Years -	Barbara Ann Karmanos Cancer Institute
C.A.P.A.B.L.E. (Cross-Training and Physical Activity: A Better Life Experience Study)	NCT03750981	Cancer Survivor...	12 week pilot i...	18 Years -	Barbara Ann Karmanos Cancer Institute

Spots Global Cancer Trial Database for 12 week pilot intervention study.