Digestive System Diseases

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Colonic Diseases

Gastrointestinal Diseases

Intestinal Diseases

Micronutrients

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Vitamins

Ascorbic Acid

Antioxidants

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Trace Elements

Vitamin C

* 2-Day Split-Dosing: The patient has taken the product in the evening before the scheduled colonoscopy and mandatory additional clear fluid. The patient has taken the second dose with mandatory additional clear fluids on the morning of the colonoscopy.
* Same Day: The patient has taken the first dose of the product on the day of the colonoscopy and take mandatory additional clear fluid. After a 1-2 hour break, the patient has taken a second dose plus additional clear mandatory fluid.

1L PEG + ASCORBIC ACID

Jose Miguel Esteban López-Jamar, MD

A retrospective study to evaluate the effectiveness and safety of 1L polyethylene glycol (PEG)+ Ascorbic acid given for bowel preparation before colonoscopy.

Observational, retrospective, and multicenter study based on the review of the existing medical records of patients followed on an outpatient basis (computerized databases and dissociated data).

The design implies the incorporation of existing anonymized data by the hospital centers without leaving any record of the code assigned to each patient. The design, therefore, avoids the possible risk of the dissemination of the personal data of patients.

Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia

An Observational, Retrospective and Multicenter Study to Evaluate the Effectiveness and Safety of 1L (PEG)+ Ascorbic Acid Given for Bowel Preparation Prior to Colonoscopy in Iberia

The proportion of patients with adequate total colon cleansing is defined as a Boston Bowel preparation scale (BBPS) score ≥ 2 in all segments (BBPS\> 6).

Proportion of patients with a high-quality cleaning in the right colon defined as a BBPS score = 3.

Proportion of colonoscopies where at least one polyp was found and removed in total and right colon

Proportion of colonoscopies where at least one adenoma is found based on histological analysis in total and right colon

Defined as the visualization of the ileocecal valve and / or appendicular orifice

Defined as the time required for the introduction of the colonoscope to reach the base of the cecum.

Defined as the minutes spent inspecting the colon wall.

Defined with a semi-quantitative scale of 1-5 (1 = totally agree, 2 = agree, 3 = Neutral, 4 = disagree, 5 = totally disagree)

Percentage of patients with adherence to the preparation, defined as ingestion of at least 75% of each of the two doses

Percentage of patients satisfied with the preparation

Quality of the preparation (BBPS\> 2 in all colon segments) depending on the dietary guideline

Patients ≥ 65 years, patients with chronic constipation, with diabetes mellitus, with hypertension, with mild to moderate renal failure and with inflammatory bowel disease.

Sub-analyzes will be carried out by country, by the reason for the colonoscopy and by the recommended dietary regimen

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia	NCT05174845	Colon Cancer Colon Disease Colon Cleansing	1L PEG + ASCORB...	18 Years -	Norgine
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia	NCT05174845	Colon Cancer Colon Disease Colon Cleansing	1L PEG + ASCORB...	18 Years -	Norgine

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