Infections

All Conditions

Symptoms and General Pathology

Wounds and Injuries

Blood and Lymph Conditions

Rare Diseases

Communicable Diseases

Hyperthermia

Neutropenia

Fever

Sepsis

Toxemia

Disease Attributes

Syndrome

Systemic Inflammatory Response Syndrome

Inflammation

Granulocytopenia

Anti-Infective Agents

All Drugs and Chemicals

Dermatologic Agents

Chlorhexidine

Anti-Bacterial Agents

Chlorhexidine gluconate

Patients receive the 3M Tegaderm CHG IV securement dressing after placement of a central venous catheter.

Patients receive the 3M Tegaderm Advanced IV securement dressing after placement of a central venous catheter.

Patients receive the 3M™ Tegaderm CHG IV securement dressing or the 3M Tegaderm Advanced IV securement dressing after placement of a central venous catheter.

3M™ Tegaderm™ CHG IV and 3M™ Tegaderm™ Advanced IV

Maria JG Vehreschild, Dr. med.

In neutropenic cancer patients, catheter-related bloodstream infections may cause severe infections and even death. To assess the prophylactic effect of a chlorhexidine coated catheter securement dressing on the incidence of catheter-related bloodstream infections, this open, randomized trial is being carried out. CHG iv Tegaderm securement dressing will be randomized in a 1:1 fashion against Tegaderm Advanced iv securement dressing.

Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients

Chlorhexidine Containing Iv-securement Dressings for the Prevention of Central Venous Catheter-related Blood Stream Infections in Neutropenic Patients: a Randomized Trial

Incidence of definite catheter-related bloodstream infection during the first 14 days after placement of the central venous catheter

Incidence of definite catheter related bloodstream infection-related severe sepsis during the first 14 days after placement of the central venous catheter

Definite catheter-related bloodstream infection-related mortality during the first 14 days after placement of the central venous catheter

Overall incidence of catheter-related bloodstream infection (evaluated by definite, probable and proven criteria)

Overall catheter-related bloodstream infection-related severe sepsis (evaluated by definite, probable and proven criteria)

Overall catheter-related bloodstream infection-related mortality(evaluated by definite, probable and proven criteria)

Time to removal of central venous catheter

Time to central venous catheter-related blood stream infections

Rate of unplanned changes of the catheter securement dressing.

Tolerability/safety is defined as the number of toxicity-related study therapy discontinuations.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients	NCT01544686	Bloodstream Inf...	3M™ Tegaderm™ C...	18 Years -	University of Cologne
Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients	NCT01544686	Bloodstream Inf...	3M™ Tegaderm™ C...	18 Years -	University of Cologne

Spots Global Cancer Trial Database for 3m™ tegaderm™ chg iv and 3m™ tegaderm™ advanced iv