Neoplasms

Digestive System Diseases

Gland and Hormone Related Diseases

All Conditions

Symptoms and General Pathology

Rare Diseases

Pancreatic Neoplasms

Biliary Tract Neoplasms

Jaundice

Jaundice, Obstructive

Hyperbilirubinemia

Skin Manifestations

Gastrointestinal Neoplasms

Digestive System Neoplasms

Endocrine Gland Neoplasms

Gastrointestinal Diseases

Pancreatic Diseases

Endocrine System Diseases

Biliary Tract Diseases

Pancreatic Cancer

Biliary Tract Cancer

6 mm Nitinol Zilver Stent

10 mm Nitinol Zilver Stent

10 mm Stainless Steel Wallstent

Douglas Howell, M.D.

This study compares the 6 mm nitinol Zilver biliary endoprostheses and the 10 mm nitinol Zilver biliary endoprostheses to the 10 mm Wallstent in appropriate patients in need of palliative treatment of malignant obstructive jaundice.

This research is being done to determine if the new, FDA-cleared Zilver metal biliary stent is better than the conventional stents. The new Zilver stent may permit more accurate placement, may avoid some potential complications and last longer than the conventional stents. The study will also examine to find the best diameter of stent by comparing standard 10 mm stents to 6 mm Zilver stents.

Malignant Obstruction ZILVER Against Routine Therapy (MOZART I)

Multicenter Prospective Randomized Controlled Trial of the Nitinol ZILVER Expandable Endoprosthesis in the Palliation of Extrahepatic Malignant Biliary Obstruction

Number of days of stent patency: The time to stent occlusion requiring re-intervention, death, loss to follow-up, or patients alive at study end without an occlusion (\>= 6 months after placement).

Biliary stents may become closed or blocked. This is also termed "Occlusion." Data for this outcome measure involve stent occlusions that required re-intervention.

Cook Group Incorporated

No adverse events were captured due to terminal patients.

6 mm Zilver

10 mm Zilver

10 mm Wallstent

Total

Age Continuous

Sex: Female, Male

Patients with Biliary Sphincterotomy

Patients without Biliary Sphincterotomy

Biliary Sphincterotomy

Patients with Previous Plastic Stent

Patients without Previous Plastic Stent

Previous Plastic Stent

Patients with Pancreatic Cancer

Patients with Metastatic Cancer

Patients with Cholangiocarcinoma

Patients with Gallbladder Cancer

Patients with Other Cancer

Patients without Tumor

Tumor Diagnosis

Bilirubin

The Karnofsky index runs from 100 to 0, where 100 is "perfect" health and 0 is death.

Spots Global Cancer Trial Database for 6 mm nitinol zilver stent