Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

All Conditions

Rare Diseases

Ovarian Neoplasms

Carcinoma, Ovarian Epithelial

Carcinoma

Endocrine Gland Neoplasms

Ovarian Diseases

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Genital Neoplasms, Female

Urogenital Neoplasms

Endocrine System Diseases

Gonadal Disorders

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Ovarian Cancer

Ovarian Epithelial Cancer

All patients will receive an injection of ICG and an injection of 99mTc nanocolloid albumin

All patients will receive an injection of both tracers in order to detect the sentinel lymph node

99mTC nanocolloid albumin injection

ICG injection

Laura Burunat, Graduate

Berta Diaz-Feijoo, Physician

Aureli Torné, Physician

Study to evaluate the diagnostic precision of ICG and 99mTc nanocolloid albumin in sentinel lymph node detection in early ovarian epithelial cancer.

Sentinel Node Detection With Technetium-99m Albumin Nanocolloid and ICG in Patients With Epithelial Ovarian Cancer

Sentinel Node Detection With Technetium-99m Albumin Nanocolloid and Indocyanine Green (ICG) in Patients With Epithelial Ovarian Cancer in Early Stages: Pilot Study

Global detection rate of sentinel lymph node in patients having received both tracers.

Diagnostic precision defined as global detection rate of sentinel lymph nodes and false negatives rate, stratified by morphologic characteristics.

Diagnostic precision defined as global detection rate of sentinel lymph nodes and false negatives rate, stratified by pathology results

Diagnostic precision defined as global detection rate of sentinel lymph nodes and false negatives rate, stratified by FIGO stage

Diagnostic precision defined as global detection rate of sentinel lymph nodes and false negatives rate, stratified by biochemistry results

Diagnostic precision defined as global detection rate of sentinel lymph nodes and false negatives rate, stratified by surgical approach

Detection rate of sentinel lymph node with 99mTC in the group of patients having received the tracer

Detection rate and false negative rate of intraoperative detector gamma probe,stratified by morphologic characteristics.

Detection rate and false negative rate of intraoperative detector gamma probe,stratified by pathology results.

Detection rate and false negative rate of intraoperative detector gamma probe,stratified by FIGO stage.

Detection rate and false negative rate of intraoperative detector gamma probe,stratified by biochemistry results.

Detection rate and false negative rate of intraoperative detector gamma probe,stratified by surgical approach.

Detection rate and false negative rate of intraoperative NIR camera,stratified by morphological characteristics

Detection rate and false negative rate of intraoperative NIR camera,stratified by pathology results.

Detection rate and false negative rate of intraoperative NIR camera,stratified by FIGO stage.

Detection rate and false negative rate of intraoperative NIR camera,stratified by biochemistry results.

Detection rate and false negative rate of intraoperative NIR camera,stratified by surgical approach.

Anatomical location of sentinel lymph node according to ICG.

Anatomical location of sentinel lymph node according to 99mTC albumin nanocolloid.

Assessment of concordance of sentinel lymph node anatomical location detected with each tracer.

Pathology ultra-staging evaluation.

The following classification will be considered according to the criteria of the American Joint Committee on Cancer (AJCC):

* Macrometastases: tumor infiltration \> 2 mm in maximum diameter.
* Micrometastases: tumor infiltration between 0.2 and 2 mm in maximum diameter.
* Isolated tumor cells or isolated cell group (CTA, GCA): clusters of cells smaller than 0.2 mm

Chirurgic and post-operative complications, directly or indirectly associated to the use of the tracers.

Spots Global Cancer Trial Database for 99mtc nanocolloid albumin injection